Theoretical prediction of antiproliferative activity against murine leukemia tumor cell line (L1210). 3D-morse descriptor and its application in computational chemistry)

QSAR and Combinatorial Science

Volumn 28, Issue 1, 2009, Pages 98-110

  Saíz Urra, Liane ^a,b   Pérez Castillo, Yunierkis ^a,b   González, Maykel Pérez ^b   Ruiz, Reinaldo Molina ^a   Cordeiro, M Natália D S ^a   Rodríguez Borges, J Enrique ^a   García Mera, Xerardo ^c  

^a UNIVERSITY OF PORTO   (Portugal)

^b CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

3D MoRSE; Anticancer activity; Indolocarbazoles derivatives; QSAR

Indexed keywords

CELL CULTURE; DISCRIMINANT ANALYSIS; DISEASES; FORECASTING; MOLECULAR GRAPHICS; THREE DIMENSIONAL COMPUTER GRAPHICS;

3D-MORSE; ANTICANCER ACTIVITIES; ANTIPROLIFERATIVE ACTIVITIES; DESCRIPTORS; INDOLOCARBAZOLE DERIVATIVE; INDOLOCARBAZOLES; ITS APPLICATIONS; LINEAR DISCRIMINANT ANALYZE; QSAR; TUMOR CELL LINES;

COMPUTATIONAL CHEMISTRY;

CARBAZOLE DERIVATIVE; REBECCAMYCIN;

ACCURACY; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; COMPUTER ANALYSIS; COMPUTER PROGRAM; CONTROLLED STUDY; CYTOTOXICITY; DISCRIMINANT ANALYSIS; DRUG STRUCTURE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; INCIDENCE; INHIBITION KINETICS; INTERMETHOD COMPARISON; LEUKEMIA L 1210; MATHEMATICAL ANALYSIS; MOUSE; NONHUMAN; POLARIZATION; PREDICTION; PRIORITY JOURNAL; PROBABILITY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SENSITIVITY AND SPECIFICITY; THEORETICAL MODEL;

MURINAE;

EID: 66149087728     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200860060     Document Type: Article

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