Syntheses and antiproliferative activities of rebeccamycin analogues bearing two 7-azaindole moieties

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 5, 2003, Pages 679-687

  Marminon, Christelle ^a   Pierré, Alain ^b   Pfeiffer, Bruno ^c   Pérez, Valérie ^b   Léonce, Stéphane ^b   Renard, Pierre ^c   Prudhomme, Michelle ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 3 [1 (BETA DEXTRO GLUCOPYRANOSYL) 1H PYRROLO[2,3 B]PYRIDIN 3 YL] 4 (1H PYRROLO[2,3 B]PYRIDIN 3 YL) 1H PYRROLE 2,5 DIONE; 12 (BETA DEXTRO GLUCOPYRANOSYL) 12,13 DIHYDRO 5H PYRIDOL[2,3 B]PYRIDOL[3',2':4,5]PYRROLO[3,2 G]PYRROLO[3,4 E]INDOLE 5,7(6H)DIONE; 6 METHYL 12 (BETA DEXTRO GLUCOPYRANOSYL) 12,13 DIHYDRO 5H PYRIDO[2,3 B]PYRIDOL[3',2':4,5]PYRROLO[3,2 G]PYRROLO[3,4 E]INDOLE 5,7(6H)DIONE; HYDROGEN; INDOLE DERIVATIVE; METHYL GROUP; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SELECTIVITY; DRUG SYNTHESIS; HYDROGEN BOND; LEUKEMIA CELL; LEUKEMIA L 1210; NONHUMAN; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; CARBAZOLES; CELL CYCLE; CELL DIVISION; HUMANS; INDICATORS AND REAGENTS; INDOLES; LEUKEMIA L1210; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MONOSACCHARIDES; QUATERNARY AMMONIUM COMPOUNDS; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037355137     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00532-1     Document Type: Article

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