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Volumn 37, Issue 5, 2002, Pages 435-440

Dimers from dechlorinated rebeccamycin: Synthesis, interaction with DNA, and antiproliferative activities

(8) Marminon, Christelle a Facompré, Michaël b Bailly, Christian b Hickman, John c Pierré, Alain c Pfeiffer, Bruno d Renard, Pierre d Prudhomme, Michelle a

a UNIVERSITÉ CLERMONT AUVERGNE (France)

b CENTRE OSCAR LAMBRET (France)

c INSTITUT DE RECHERCHES SERVIER (France)

d INSTITUT DE RECHERCHES INTERNATIONALES SERVIER (France)

Author keywords

Antitumour agents; Dimers; DNA intercalators; Rebeccamycin

Indexed keywords

1,4 BIS[6 [12 (4 O METHYL BETA DEXTRO GLUCOPYRANOSYL) 6,7,12,13 TETRAHYDROINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7 DIONE]]METHYLBENZENE; ANTINEOPLASTIC AGENT; DEOXYRIBONUCLEASE I; DIETHYL 2 [6 [12 (4 O METHYL BETA DEXTRO GLUCOPYRANOSYL) 6,7,12,13 TETRAHYDROINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7 DIONE]] 1,3 PROPANEDIAMINE; REBECCAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; COLON CARCINOMA; CONTROLLED STUDY; DECHLORINATION; DNA FOOTPRINTING; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DNA INTERACTION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL; MELTING POINT; MITOSIS INHIBITION; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CARBAZOLES; CELL DIVISION; CHLORINE; DIMERIZATION; DNA; DNA FOOTPRINTING; DNA TOPOISOMERASES, TYPE I; HUMANS; INDOLES; TUMOR CELLS, CULTURED;

EID: 0036241361 PISSN: 02235234 EISSN: None Source Type: Journal
DOI: 10.1016/S0223-5234(02)01350-8 Document Type: Article

Times cited : (9)

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