Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embryonic stem cells in a rat model of retinal degeneration

Molecular Vision

Volumn 15, Issue , 2009, Pages 962-973

  Gregory Evans, Kevin ^a,b   Chang, Francis ^a   Hodges, Matthew D ^a   Gregory Evans, Cheryl Y ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; RHODOPSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL BASED GENE THERAPY; CELL COUNT; CELL SECRETION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; EMBRYONIC STEM CELL; EX VIVO STUDY; GENE DELIVERY SYSTEM; GENETIC ENGINEERING; HISTOPATHOLOGY; HYPERPLASIA; IMMUNOFLUORESCENCE; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PERIPHERAL CIRCULATION; PHOTORECEPTOR; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; RETINA DETACHMENT; RETINA STRUCTURE; TISSUE STRUCTURE; TREATMENT DURATION;

ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; GENE THERAPY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEINS; HISTOCYTOCHEMISTRY; INJECTIONS; MICE; NEUROPROTECTIVE AGENTS; RATS; RETINA; RETINAL DEGENERATION; RETINITIS PIGMENTOSA; STATISTICS, NONPARAMETRIC; STEM CELL TRANSPLANTATION; TRANSFECTION; VITREOUS BODY;

EID: 65949122960     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

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