Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation

Experimental Eye Research

Volumn 74, Issue 6, 2002, Pages 719-735

  Bok, Dean ^a,b,c   Yasumura, Douglas ^d   Matthes, Michael T ^d   Ruiz, Alberto ^b   Duncan, Jacque L ^d   Chappelow, Aimee V ^d   Zolutukhin, Sergei ^e   Hauswirth, William ^e   LaVail, Matthew M ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JULES STEIN EYE INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

AAV; Ciliary neurotrophic factor; CNTF; Cytokine; Gene therapy; Mice; Photoreceptor; rds; Rescue; Retinitis pigmentosa

Indexed keywords

ADENOVIRUS VECTOR; BETA ACTIN; CILIARY NEUROTROPHIC FACTOR; PERIPHERIN; RECOMBINANT CILIARY NEUROTROPHIC FACTOR;

A WAVE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B WAVE; CELL NUCLEUS; CELL PROTECTION; CELL STIMULATION; CHICKEN; CONTROLLED STUDY; CYTOMEGALOVIRUS; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ELECTRORETINOGRAM; EUCHROMATIN; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENE TARGETING; GENE THERAPY; GENETIC CODE; MOUSE MUTANT; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION; REPRODUCIBILITY; RETINA; RETINA CELL; RETINA DEGENERATION; RETINA ROD; TOXICITY; VIRUS RECOMBINANT; VITREOUS BODY;

EID: 0036349623     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.2002.1176     Document Type: Article

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