-
1
-
-
0034102337
-
ATR disruption leads to chromosomal fragmentation and early embryonic lethality
-
Brown EJ, Baltimore D. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev 2000; 14:397-402. (Pubitemid 30131885)
-
(2000)
Genes and Development
, vol.14
, Issue.4
, pp. 397-402
-
-
Brown, E.J.1
Baltimore, D.2
-
2
-
-
0037335861
-
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
-
DOI 10.1101/gad.1067403
-
Brown EJ, Baltimore D. Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Genes Dev 2003; 17:615-628 (Pubitemid 36307546)
-
(2003)
Genes and Development
, vol.17
, Issue.5
, pp. 615-628
-
-
Brown, E.J.1
Baltimore, D.2
-
3
-
-
17644432403
-
Chk1 is an essential kinase that is regulated by atr and required for the G(2)/M DNA damage checkpoint
-
Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, et al. Chk1 is an essential kinase that is regulated by atr and required for the G(2)/M DNA damage checkpoint. Genes Dev 2000; 14:1448-1459
-
(2000)
Genes Dev
, vol.14
, pp. 1448-1459
-
-
Liu, Q.1
Guntuku, S.2
Cui, X.S.3
Matsuoka, S.4
Cortez, D.5
Tamai, K.6
-
4
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez D, Guntuku S, Qin J, Elledge SJ. ATR and ATRIP: Partners in checkpoint signaling. Science 2001; 294:1713-1776
-
(2001)
Science
, vol.294
, pp. 1713-1776
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
5
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001; 15:2177-2296
-
(2001)
Genes Dev
, vol.15
, pp. 2177-2296
-
-
Abraham, R.T.1
-
6
-
-
0036849432
-
Checking on the fork: The DNA-replication stress-response pathway
-
Osborn AJ, Elledge SJ, Zou L. Checking on the fork: The DNA-replication stress-response pathway. Trends Cell Biol 2002; 12:509-516
-
(2002)
Trends Cell Biol
, vol.12
, pp. 509-516
-
-
Osborn, A.J.1
Elledge, S.J.2
Zou, L.3
-
7
-
-
33847779345
-
ATM and ATR: Components of an integrated circuit
-
Hurley PJ, Bunz F. ATM and ATR: Components of an integrated circuit. Cell Cycle 2007; 6:414-417
-
(2007)
Cell Cycle
, vol.6
, pp. 414-417
-
-
Hurley, P.J.1
Bunz, F.2
-
8
-
-
34250010317
-
Chk1 regulates the density of active replication origins during the vertebrate S phase
-
DOI 10.1038/sj.emboj.7601714, PII 7601714
-
Maya-Mendoza A, Petermann E, Gillespie DA, Caldecott KW, Jackson DA. Chk1 regulates the density of active replication origins during the vertebrate S phase. EMBO J 2007; 26:2719-2731 (Pubitemid 46884282)
-
(2007)
EMBO Journal
, vol.26
, Issue.11
, pp. 2719-2731
-
-
Maya-Mendoza, A.1
Petermann, E.2
Gillespie, D.A.F.3
Caldecott, K.W.4
Jackson, D.A.5
-
9
-
-
33645825609
-
Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase
-
Petermann E, Maya-Mendoza A, Zachos G, Gillespie DA, Jackson DA, Caldecott KW. Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase. Mol Cell Biol 2006; 26:3319-3326
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3319-3326
-
-
Petermann, E.1
Maya-Mendoza, A.2
Zachos, G.3
Gillespie, D.A.4
Jackson, D.A.5
Caldecott, K.W.6
-
10
-
-
20244388673
-
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
-
Syljuasen RG, Sorensen CS, Hansen LT, Fugger K, Lundin C, Johansson F, et al. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol Cell Biol 2005; 25:3553-3562
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3553-3562
-
-
Syljuasen, R.G.1
Sorensen, C.S.2
Hansen, L.T.3
Fugger, K.4
Lundin, C.5
Johansson, F.6
-
11
-
-
0037074013
-
ATR regulates fragile site stability
-
DOI 10.1016/S0092-8674(02)01113-3
-
Casper AM, Nghiem P, Arlt MF, Glover TW. ATR regulates fragile site stability. Cell 2002; 111:779-789 (Pubitemid 36106400)
-
(2002)
Cell
, vol.111
, Issue.6
, pp. 779-789
-
-
Casper, A.M.1
Nghiem, P.2
Arlt, M.F.3
Glover, T.W.4
-
12
-
-
0033636737
-
Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage
-
Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, et al. Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage. Mol Cell 2000; 6:649-659
-
(2000)
Mol Cell
, vol.6
, pp. 649-659
-
-
Costanzo, V.1
Robertson, K.2
Ying, C.Y.3
Kim, E.4
Avvedimento, E.5
Gottesman, M.6
-
13
-
-
0036510055
-
The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
-
Falck J, Petrini JH, Williams BR, Lukas J, Bartek J. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet 2002; 30:290-294
-
(2002)
Nat Genet
, vol.30
, pp. 290-294
-
-
Falck, J.1
Petrini, J.H.2
Williams, B.R.3
Lukas, J.4
Bartek, J.5
-
14
-
-
0012966157
-
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A
-
Sorensen CS, Syljuasen RG, Falck J, Schroeder T, Ronnstrand L, Khanna KK, et al. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell 2003; 3:247-258
-
(2003)
Cancer Cell
, vol.3
, pp. 247-258
-
-
Sorensen, C.S.1
Syljuasen, R.G.2
Falck, J.3
Schroeder, T.4
Ronnstrand, L.5
Khanna, K.K.6
-
15
-
-
0034717309
-
Rapid destruction of human Cdc25A in response to DNA damage
-
Mailand N, Falck J, Lukas C, Syljuasen RG, Welcker M, Bartek J, et al. Rapid destruction of human Cdc25A in response to DNA damage. Science 2000; 288:1425-1429
-
(2000)
Science
, vol.288
, pp. 1425-1429
-
-
Mailand, N.1
Falck, J.2
Lukas, C.3
Syljuasen, R.G.4
Welcker, M.5
Bartek, J.6
-
16
-
-
58549089689
-
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
-
Wilsker D, Petermann E, Helleday T, Bunz F. Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control. Proc Natl Acad Sci USA 2008; 105:20752-20757
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20752-20757
-
-
Wilsker, D.1
Petermann, E.2
Helleday, T.3
Bunz, F.4
-
17
-
-
34147206546
-
Specific role of Chk1 phosphorylations in cell survival and checkpoint activation
-
DOI 10.1128/MCB.01611-06
-
Niida H, Katsuno Y, Banerjee B, Hande MP, Nakanishi M. Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol Cell Biol 2007; 27:2572-2581 (Pubitemid 46581348)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.7
, pp. 2572-2581
-
-
Niida, H.1
Katsuno, Y.2
Banerjee, B.3
Hande, M.P.4
Nakanishi, M.5
-
18
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
DOI 10.1128/MCB.21.13.4129-4139.2001
-
Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 2001; 21:4129-4139 (Pubitemid 32565295)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.13
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
20
-
-
4444345565
-
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
-
Kramer A, Mailand N, Lukas C, Syljuasen RG, Wilkinson CJ, Nigg EA, et al. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat Cell Biol 2004; 6:884-891
-
(2004)
Nat Cell Biol
, vol.6
, pp. 884-891
-
-
Kramer, A.1
Mailand, N.2
Lukas, C.3
Syljuasen, R.G.4
Wilkinson, C.J.5
Nigg, E.A.6
-
21
-
-
35848964048
-
DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function
-
Loffler H, Bochtler T, Fritz B, Tews B, Ho AD, Lukas J, et al. DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function. Cell Cycle 2007; 6:2541-2548
-
(2007)
Cell Cycle
, vol.6
, pp. 2541-2548
-
-
Loffler, H.1
Bochtler, T.2
Fritz, B.3
Tews, B.4
Ho, A.D.5
Lukas, J.6
-
22
-
-
33751232308
-
Chk1-dependent regulation of Cdc25B functions to coordinate mitotic events
-
Loffler H, Rebacz B, Ho AD, Lukas J, Bartek J, Kramer A. Chk1-dependent regulation of Cdc25B functions to coordinate mitotic events. Cell Cycle 2006; 5:2543-2547
-
(2006)
Cell Cycle
, vol.5
, pp. 2543-2547
-
-
Loffler, H.1
Rebacz, B.2
Ho, A.D.3
Lukas, J.4
Bartek, J.5
Kramer, A.6
-
23
-
-
34249065507
-
Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression
-
DOI 10.1371/journal.pbio.0050123
-
Lindqvist A, van Zon W, Karlsson Rosenthal C, Wolthuis RM. Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression. PLoS Biol 2007; 5:123. (Pubitemid 46790402)
-
(2007)
PLoS Biology
, vol.5
, Issue.5
, pp. 1127-1137
-
-
Lindqvist, A.1
Van Zon, W.2
Rosenthal, C.K.3
Wolthuis, R.M.F.4
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