-
1
-
-
0036480194
-
Emerging structure of the nicotinic acetylcholine receptors
-
The classic comprehensive review describing the progress in high-resolution investigations of AChR.
-
Karlin A. Emerging structure of the nicotinic acetylcholine receptors. Nat Rev Neurosci 3 (2002) 102-114. The classic comprehensive review describing the progress in high-resolution investigations of AChR.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 102-114
-
-
Karlin, A.1
-
2
-
-
40649084279
-
Nicotinic receptors, allosteric proteins and medicine
-
Changeux J.P., and Taly A. Nicotinic receptors, allosteric proteins and medicine. Trends Mol Med 14 (2008) 93-102
-
(2008)
Trends Mol Med
, vol.14
, pp. 93-102
-
-
Changeux, J.P.1
Taly, A.2
-
3
-
-
33645302360
-
Recent advances in Cys-loop receptor structure and function
-
Sine S.M., and Engel A.G. Recent advances in Cys-loop receptor structure and function. Nature 440 (2006) 448-455
-
(2006)
Nature
, vol.440
, pp. 448-455
-
-
Sine, S.M.1
Engel, A.G.2
-
4
-
-
34447639624
-
Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity
-
Kalamida D., Poulas K., Avramopoulou V., Fostieri E., Lagoumintzis G., Lazaridis K., Sideri A., Zouridakis M., and Tzartos S.J. Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity. FEBS J 274 (2007) 3799-3845
-
(2007)
FEBS J
, vol.274
, pp. 3799-3845
-
-
Kalamida, D.1
Poulas, K.2
Avramopoulou, V.3
Fostieri, E.4
Lagoumintzis, G.5
Lazaridis, K.6
Sideri, A.7
Zouridakis, M.8
Tzartos, S.J.9
-
5
-
-
0032478818
-
The structure of the potassium channel: molecular basis of K+ conduction and selectivity
-
The first X-ray structure of a voltage dependent ion channel.
-
Doyle D.A., Morais Cabral J., Pfuetzner R.A., Kuo A., Gulbis J.M., Cohen S.L., Chait B.T., and MacKinnon R. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280 (1998) 69-77. The first X-ray structure of a voltage dependent ion channel.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
6
-
-
0035902187
-
A glia-derived acetylcholine-binding protein that modulates synaptic transmission
-
A breakthrough discovery of the greatest importance for AChR structural research.
-
Smit A.B., Syed N.I., Schaap D., van Minnen J., Klumperman J., Kits K.S., Lodder H., van der Schors R.C., van Elk R., Sorgedrager B., et al. A glia-derived acetylcholine-binding protein that modulates synaptic transmission. Nature 411 (2001) 261-268. A breakthrough discovery of the greatest importance for AChR structural research.
-
(2001)
Nature
, vol.411
, pp. 261-268
-
-
Smit, A.B.1
Syed, N.I.2
Schaap, D.3
van Minnen, J.4
Klumperman, J.5
Kits, K.S.6
Lodder, H.7
van der Schors, R.C.8
van Elk, R.9
Sorgedrager, B.10
-
7
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K., van Dijk W.J., Klaassen R.V., Schuurmans M., van Der Oost J., Smit A.B., and Sixma T.K. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 411 (2001) 269-276
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
8
-
-
1842475289
-
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
-
Celie P.H., van Rossum-Fikkert S.E., van Dijk W.J., Brejc K., Smit A.B., and Sixma T.K. Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures. Neuron 41 (2004) 907-914
-
(2004)
Neuron
, vol.41
, pp. 907-914
-
-
Celie, P.H.1
van Rossum-Fikkert, S.E.2
van Dijk, W.J.3
Brejc, K.4
Smit, A.B.5
Sixma, T.K.6
-
9
-
-
18444411922
-
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors
-
Mapping the ligand-binding site with a peptide neurotoxin.
-
Bourne Y., Talley T.T., Hansen S.B., Taylor P., and Marchot P. Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. EMBO J 24 (2005) 1512-1522. Mapping the ligand-binding site with a peptide neurotoxin.
-
(2005)
EMBO J
, vol.24
, pp. 1512-1522
-
-
Bourne, Y.1
Talley, T.T.2
Hansen, S.B.3
Taylor, P.4
Marchot, P.5
-
10
-
-
1642450641
-
Snake and snail toxins acting on nicotinic acetylcholine receptors: fundamental aspects and medical applications
-
Tsetlin V.I., and Hucho F. Snake and snail toxins acting on nicotinic acetylcholine receptors: fundamental aspects and medical applications. FEBS Lett 557 (2004) 9-13
-
(2004)
FEBS Lett
, vol.557
, pp. 9-13
-
-
Tsetlin, V.I.1
Hucho, F.2
-
11
-
-
33751049816
-
Conotoxins down under
-
Norton R.S., and Olivera B.M. Conotoxins down under. Toxicon 48 (2006) 780-798
-
(2006)
Toxicon
, vol.48
, pp. 780-798
-
-
Norton, R.S.1
Olivera, B.M.2
-
12
-
-
22144470470
-
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant
-
Celie P.H., Kasheverov I.E., Mordvintsev D.Y., Hogg R.C., van Nierop P., van ElkR, van Rossum-Fikkert S.E., Zhmak M.N., Bertrand D., Tsetlin V., et al. Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. Nat Struct Mol Biol 12 (2005) 582-588
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 582-588
-
-
Celie, P.H.1
Kasheverov, I.E.2
Mordvintsev, D.Y.3
Hogg, R.C.4
van Nierop, P.5
van ElkR6
van Rossum-Fikkert, S.E.7
Zhmak, M.N.8
Bertrand, D.9
Tsetlin, V.10
-
13
-
-
27144473613
-
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen S.B., Sulzenbacher G., Huxford T., Marchot P., Taylor P., and Bourne Y. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J 24 (2005) 3635-3646
-
(2005)
EMBO J
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
Sulzenbacher, G.2
Huxford, T.3
Marchot, P.4
Taylor, P.5
Bourne, Y.6
-
14
-
-
33644870155
-
Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP
-
Ulens C., Hogg R.C., Celie P.H., Bertrand D., Tsetlin V., Smit A.B., and Sixma T.K. Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. Proc Natl Acad Sci U S A 103 (2006) 3615-3620
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3615-3620
-
-
Ulens, C.1
Hogg, R.C.2
Celie, P.H.3
Bertrand, D.4
Tsetlin, V.5
Smit, A.B.6
Sixma, T.K.7
-
15
-
-
34548056414
-
AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity
-
Dutertre S., Ulens C., Büttner R., Fish A., van Elk R., Kendel Y., Hopping G., Alewood P.F., Schroeder C., Nicke A., et al. AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. EMBO J 26 (2007) 3858-3867
-
(2007)
EMBO J
, vol.26
, pp. 3858-3867
-
-
Dutertre, S.1
Ulens, C.2
Büttner, R.3
Fish, A.4
van Elk, R.5
Kendel, Y.6
Hopping, G.7
Alewood, P.F.8
Schroeder, C.9
Nicke, A.10
-
16
-
-
28044455671
-
A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins
-
MordvintsevDY, Polyak Y.L., Levtsova O.V., Tourleigh Y.V., Kasheverov I.E., Shaitan K.V., Utkin Y.N., and Tsetlin V.I. A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins. Comput Biol Chem 29 (2005) 398-411
-
(2005)
Comput Biol Chem
, vol.29
, pp. 398-411
-
-
MordvintsevDY1
Polyak, Y.L.2
Levtsova, O.V.3
Tourleigh, Y.V.4
Kasheverov, I.E.5
Shaitan, K.V.6
Utkin, Y.N.7
Tsetlin, V.I.8
-
17
-
-
33748756414
-
Alpha-conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors
-
Kasheverov I.E., Zhmak M.N., Vulfius C.A., Gorbacheva E.V., Mordvintsev D.Y., Utkin Y.N., van Elk R., Smit A.B., and Tsetlin V.I. Alpha-conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors. FEBS J 273 (2006) 4470-4481
-
(2006)
FEBS J
, vol.273
, pp. 4470-4481
-
-
Kasheverov, I.E.1
Zhmak, M.N.2
Vulfius, C.A.3
Gorbacheva, E.V.4
Mordvintsev, D.Y.5
Utkin, Y.N.6
van Elk, R.7
Smit, A.B.8
Tsetlin, V.I.9
-
18
-
-
44249110008
-
Synthesis and characterization of 125I-alpha-conotoxin ArIB[V11L;V16A], a selective alpha7 nicotinic acetylcholine receptor antagonist
-
Whiteaker P., Marks M.J., Christensen S., Dowell C., Collins A.C., and McIntosh J.M. Synthesis and characterization of 125I-alpha-conotoxin ArIB[V11L;V16A], a selective alpha7 nicotinic acetylcholine receptor antagonist. J Pharmacol Exp Ther 325 (2008) 910-919
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 910-919
-
-
Whiteaker, P.1
Marks, M.J.2
Christensen, S.3
Dowell, C.4
Collins, A.C.5
McIntosh, J.M.6
-
19
-
-
4344616080
-
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
-
An informative model construct visualizing the coupling between ligand-binding site and ion channel.
-
Bouzat C., Gumilar F., Spitzmaul G., Wang H.L., Rayes D., Hansen S.B., Taylor P., and Sine S.M. Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature 430 (2004) 896-900. An informative model construct visualizing the coupling between ligand-binding site and ion channel.
-
(2004)
Nature
, vol.430
, pp. 896-900
-
-
Bouzat, C.1
Gumilar, F.2
Spitzmaul, G.3
Wang, H.L.4
Rayes, D.5
Hansen, S.B.6
Taylor, P.7
Sine, S.M.8
-
20
-
-
58149193160
-
Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties
-
Zouridakis M., Zisimopoulou P., Eliopoulos E., Poulas K., and Tzartos S.J. Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties. Biochim Biophys Acta 1794 (2009) 355-366
-
(2009)
Biochim Biophys Acta
, vol.1794
, pp. 355-366
-
-
Zouridakis, M.1
Zisimopoulou, P.2
Eliopoulos, E.3
Poulas, K.4
Tzartos, S.J.5
-
21
-
-
34547520128
-
Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 Å resolution
-
A high-resolution structure of the AChR extracellular domain with a bound antagonist.
-
Dellisanti C.D., Yao Y., Stroud J.C., Wang Z.Z., and Chen L. Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 Å resolution. Nat Neurosci 10 (2007) 953-962. A high-resolution structure of the AChR extracellular domain with a bound antagonist.
-
(2007)
Nat Neurosci
, vol.10
, pp. 953-962
-
-
Dellisanti, C.D.1
Yao, Y.2
Stroud, J.C.3
Wang, Z.Z.4
Chen, L.5
-
22
-
-
46149085900
-
Spontaneous conformational change and toxin binding in alpha7 acetylcholine receptor: insight into channel activation and inhibition
-
Yi M., Tjong H., and Zhou H.X. Spontaneous conformational change and toxin binding in alpha7 acetylcholine receptor: insight into channel activation and inhibition. Proc Natl Acad Sci U S A 105 (2008) 8280-8285
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 8280-8285
-
-
Yi, M.1
Tjong, H.2
Zhou, H.X.3
-
23
-
-
44449105649
-
Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein
-
Bertaccini E.J., Lindahl E., Sixma T., and Trudell J.R. Effect of cobratoxin binding on the normal mode vibration within acetylcholine binding protein. J Chem Inf Model 48 (2008) 855-860
-
(2008)
J Chem Inf Model
, vol.48
, pp. 855-860
-
-
Bertaccini, E.J.1
Lindahl, E.2
Sixma, T.3
Trudell, J.R.4
-
24
-
-
34548672882
-
Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes
-
Taylor P., Talley T.T., Radic' Z., Hansen S.B., Hibbs R.E., and Shi J. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochem Pharmacol 74 (2007) 1164-1171
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1164-1171
-
-
Taylor, P.1
Talley, T.T.2
Radic', Z.3
Hansen, S.B.4
Hibbs, R.E.5
Shi, J.6
-
25
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
-
Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution. J Mol Biol 346 (2005) 967-989
-
(2005)
J Mol Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
26
-
-
27744608733
-
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
-
Lummis S.C., Beene D.L., Lee L.W., Lester H.A., Broadhurst R.W., and Dougherty D.A. Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel. Nature 438 (2005) 248-252
-
(2005)
Nature
, vol.438
, pp. 248-252
-
-
Lummis, S.C.1
Beene, D.L.2
Lee, L.W.3
Lester, H.A.4
Broadhurst, R.W.5
Dougherty, D.A.6
-
27
-
-
33846106078
-
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family
-
Bocquet N., Prado de Carvalho L., Cartaud J., Neyton J., Le Poupon C., Taly A., Grutter T., Changeux J.P., and Corringer P.J. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature 445 (2007) 116-119
-
(2007)
Nature
, vol.445
, pp. 116-119
-
-
Bocquet, N.1
Prado de Carvalho, L.2
Cartaud, J.3
Neyton, J.4
Le Poupon, C.5
Taly, A.6
Grutter, T.7
Changeux, J.P.8
Corringer, P.J.9
-
28
-
-
41149168686
-
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
-
The first X-ray structure of a ligand gated ion channel, a model with great similarities to the acetylcholine binding protein and the AChR.
-
Hilf R.J., and Dutzler R. X-ray structure of a prokaryotic pentameric ligand-gated ion channel. Nature 452 (2008) 375-379. The first X-ray structure of a ligand gated ion channel, a model with great similarities to the acetylcholine binding protein and the AChR.
-
(2008)
Nature
, vol.452
, pp. 375-379
-
-
Hilf, R.J.1
Dutzler, R.2
-
29
-
-
58149267953
-
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
-
Bocquet N., Nury H., Baaden M., Le Poupon C., Changeux J.P., Delarue M., and Corringer P.J. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature 457 (2009) 111-114
-
(2009)
Nature
, vol.457
, pp. 111-114
-
-
Bocquet, N.1
Nury, H.2
Baaden, M.3
Le Poupon, C.4
Changeux, J.P.5
Delarue, M.6
Corringer, P.J.7
-
30
-
-
58149242730
-
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
-
Hilf R.J., and Dutzler R. Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel. Nature 457 (2009) 115-118
-
(2009)
Nature
, vol.457
, pp. 115-118
-
-
Hilf, R.J.1
Dutzler, R.2
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