Inhibition of the mammalian transcription factor LSF induces S-phase-dependent apoptosis by downregulating thymidylate synthases expression

EMBO Journal

Volumn 19, Issue 17, 2000, Pages 4665-4675

  Powell, Christina M H ^a,b,c   Rudge, Thomas L ^d   Zhu, Quan ^a,b,e   Johnson, Lee F ^d   Hansen, Ulla ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c Boston University   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e IntraImmune Therapies Inc   (United States)

Author keywords

Apoptosis; Cell cycle progression; G1 S transition; LSF; Thymidylate synthase

Indexed keywords

FLOXURIDINE; MESSENGER RNA; THYMIDINE; THYMIDYLATE SYNTHASE; THYMIDYLATE SYNTHASE INHIBITOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LSF; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL SURVIVAL; CONTROLLED STUDY; DNA REPLICATION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA; DNA-BINDING PROTEINS; DOWN-REGULATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; RNA-BINDING PROTEINS; S PHASE; SPECIES SPECIFICITY; THYMIDYLATE SYNTHASE; TRANSCRIPTION FACTORS;

EID: 0034282755     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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