The zinc finger protein Zn72D and DEAD box helicase Belle interact and control maleless mRNA and protein levels

BMC Molecular Biology

Volumn 10, Issue , 2009, Pages

  Worringer, Kathleen A ^a,b   Chu, Feixia ^a,c   Panning, Barbara ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^c UNIVERSITY OF NEW HAMPSHIRE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BELLE PROTEIN; DEAD BOX PROTEIN; DROSOPHILA PROTEIN; MALELESS PROTEIN; MESSENGER RNA; PROTEIN ZN72D; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; CYCLOHEXIMIDE; DNA BINDING PROTEIN; PROTEIN SYNTHESIS INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION REGULATION; INSECT CELL; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RNA SPLICING; TRANSLATION REGULATION; WILD TYPE; X CHROMOSOME; ANIMAL; CELL LINE; DROSOPHILA MELANOGASTER; DRUG EFFECT; ENZYMOLOGY; GENE SILENCING; GENETICS; METABOLISM;

ANIMALS; CELL LINE; CYCLOHEXIMIDE; DEAD-BOX RNA HELICASES; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; PROTEIN SYNTHESIS INHIBITORS; RNA SPLICING; RNA, MESSENGER; X CHROMOSOME;

EID: 65649103415     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-10-33     Document Type: Article

References (45)

1. Huang Y Gattoni R Stevenin J Steitz JA SR splicing factors serve as adapter proteins for TAP-dependent mRNA export Mol Cell 2003, 11(3):837-843. 10.1016/S1097-2765(03)00089-3 12667464
2. Huang Y Steitz JA Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA Mol Cell 2001, 7(4):899-905. 10.1016/ S1097-2765(01)00233-7 11336712
3. Sanford JR Gray NK Beckmann K Caceres JF A novel role for shuttling SR proteins in mRNA translation Genes Dev 2004, 18(7):755-768. 387416 15082528 10.1101/gad.286404
4. Caceres JF Screaton GR Krainer AR A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm Genes Dev 1998, 12(1):55-66. 316398 9420331 10.1101/gad.12.1.55
5. Hachet O Ephrussi A Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localization Nature 2004, 428(6986):959-963. 10.1038/ nature02521 15118729
6. Hachet O Ephrussi A Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport Curr Biol 2001, 11(21):1666-1674. 10.1016/S0960-9822(01)00508-5 11696323
7. Mohr SE Dillon ST Boswell RE The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis Genes Dev 2001, 15(21):2886-2899. 312802 11691839
8. Newmark PA Boswell RE The mago nashi locus encodes an essential product required for germ plasm assembly in Drosophila Development 1994, 120(5):1303-1313. 8026338
9. Lucchesi JC Kelly WG Panning B Chromatin remodeling in dosage compensation Annu Rev Genet 2005, 39:615-651. 10.1146/ annurev.genet.39.073003.094210 16285873
10. Worringer KA Panning B Zinc finger protein Zn72D promotes productive splicing of the maleless transcript Mol Cell Biol 2007, 27(24):8760-8769. 2169391 17923683 10.1128/MCB.01415-07
11. Johnstone O Deuring R Bock R Linder P Fuller MT Lasko P Belle is a Drosophila DEAD-box protein required for viability and in the germ line Dev Biol 2005, 277(1):92-101. 10.1016/j.ydbio.2004.09.009 15572142
12. Giot L Bader JS Brouwer C Chaudhuri A Kuang B Li Y Hao YL Ooi CE Godwin B Vitols E et al A protein interaction map of Drosophila melanogaster Science 2003, 302(5651):1727-1736. 10.1126/science.1090289 14605208
13. FlyExpress An image-matching web-tool for finding genes with overlapping patterns of expression in Drosophila embryos http://www.flyexpress.net
14. Wan L Dockendorff TC Jongens TA Dreyfuss G Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile × mental retardation protein Mol Cell Biol 2000, 20(22):8536-8547. 102159 11046149 10.1128/MCB.20.22.8536-8547.2000
15. Tomancak P Berman BP Beaton A Weiszmann R Kwan E Hartenstein V Celniker SE Rubin GM Global analysis of patterns of gene expression during Drosophila embryogenesis Genome Biol 2007, 8(7):R145. 2323238 17645804 10.1186/gb-2007-8-7-r145
16. Hase ME Yalamanchili P Visa N The Drosophila heterogeneous nuclear ribonucleoprotein M protein, HRP59, regulates alternative splicing and controls the production of its own mRNA J Biol Chem 2006, 281(51):39135-39141. 10.1074/jbc.M604235200 17077090
17. Kiesler E Hase ME Brodin D Visa N Hrp59, an hnRNP M protein in Chironomus and Drosophila, binds to exonic splicing enhancers and is required for expression of a subset of mRNAs J Cell Biol 2005, 168(7):1013-1025. 2171850 15781475 10.1083/jcb.200407173
18. Dorner S Lum L Kim M Paro R Beachy PA Green R A genomewide screen for components of the RNAi pathway in Drosophila cultured cells Proc Natl Acad Sci USA 2006, 103(32):11880-11885. 1525048 16882716 10.1073/ pnas.0605210103
19. Hovemann B Richter S Walldorf U Cziepluch C Two genes encode related cytoplasmic elongation factors 1 alpha (EF-1 alpha) in Drosophila melanogaster with continuous and stage specific expression Nucleic Acids Res 1988, 16(8):3175-3194. 336487 3131735 10.1093/nar/16.8.3175
20. Condeelis J Elongation factor 1 alpha, translation and the cytoskeleton Trends Biochem Sci 1995, 20(5):169-170. 10.1016/S0968-0004(00)88998-7 7610475
21. Costa A Wang Y Dockendorff TC Erdjument-Bromage H Tempst P Schedl P Jongens TA The Drosophila fragile × protein functions as a negative regulator in the orb autoregulatory pathway Dev Cell 2005, 8(3):331-342. 10.1016/j.devcel.2005.01.011 15737929
22. Geng C Macdonald PM Imp associates with squid and Hrp48 and contributes to localized expression of gurken in the oocyte Mol Cell Biol 2006, 26(24):9508-9516. 1698525 17030623 10.1128/MCB.01136-06
23. Ishizuka A Siomi MC Siomi H A Drosophila fragile × protein interacts with components of RNAi and ribosomal proteins Genes Dev 2002, 16(19):2497-2508. 187455 12368261 10.1101/gad.1022002
24. Mangus DA Evans MC Jacobson A Poly(A)-binding proteins: Multifunctional scaffolds for the post-transcriptional control of gene expression Genome Biol 2003, 4(7):223. 193625 12844354 10.1186/gb-2003-4-7-223
25. Xu K Bogert BA Li W Su K Lee A Gao FB The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1 Curr Biol 2004, 14(12):1025-1034. 10.1016/j.cub.2004.05.055 15202995
26. Hammond SM Boettcher S Caudy AA Kobayashi R Hannon GJ Argonaute2, a link between genetic and biochemical analyses of RNAi Science 2001, 293(5532):1146-1150. 10.1126/science.1064023 11498593
27. Lee CS Dias AP Jedrychowski M Patel AH Hsu JL Reed R Human DDX3 functions in translation and interacts with the translation initiation factor eIF3 Nucleic Acids Res 2008, 36(14):4708-4718. 2504307 18628297 10.1093/nar/gkn454
28. Chuang RY Weaver PL Liu Z Chang TH Requirement of the DEAD-Box protein ded1p for messenger RNA translation Science 1997, 275(5305):1468-1471. 10.1126/science.275.5305.1468 9045610
29. Burckin T Nagel R Mandel-Gutfreund Y Shiue L Clark TA Chong JL Chang TH Squazzo S Hartzog G Ares M Jr Exploring functional relationships between components of the gene expression machinery Nature structural & molecular biology 2005, 12(2):175-182. 10.1038/nsmb891 15702072
30. Jamieson DJ Rahe B Pringle J Beggs JD A suppressor of a yeast splicing mutation (prp8-1) encodes a putative ATP-dependent RNA helicase Nature 1991, 349(6311):715-717. 10.1038/349715a0 1996139
31. Stevens SW Ryan DE Ge HY Moore RE Young MK Lee TD Abelson J Composition and functional characterization of the yeast spliceosomal penta-snRNP Mol Cell 2002, 9(1):31-44. 10.1016/S1097-2765(02)00436-7 11804584
32. Merz C Urlaub H Will CL Luhrmann R Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment Rna 2007, 13(1):116-128. 1705747 17095540 10.1261/rna.336807
33. Shih JW Tsai TY Chao CH Wu Lee YH Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein Oncogene 2008, 27(5):700-714. 10.1038/ sj.onc.1210687 17667941
34. Zhou Z Licklider LJ Gygi SP Reed R Comprehensive proteomic analysis of the human spliceosome Nature 2002, 419(6903):182-185. 10.1038/ nature01031 12226669
35. Lai MC Lee YH Tarn WY The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control Mol Biol Cell 2008, 19(9):3847-3858. 2526709 18596238 10.1091/mbc.E07-12-1264
36. Nashchekin D Zhao J Visa N Daneholt B A novel Ded1-like RNA helicase interacts with the Y-box protein ctYB-1 in nuclear mRNP particles and in polysomes J Biol Chem 2006, 281(20):14263-14272. 10.1074/jbc.M600262200 16556597
37. Ishaq M Hu J Wu X Fu Q Yang Y Liu Q Guo D Knockdown of Cellular RNA Helicase DDX3 by Short Hairpin RNAs Suppresses HIV-1 Viral Replication Without Inducing Apoptosis Mol Biotechnol 2008. 18259889
38. Kanai Y Dohmae N Hirokawa N Kinesin transports RNA: Isolation and characterization of an RNA-transporting granule Neuron 2004, 43(4):513-525. 10.1016/j.neuron.2004.07.022 15312650
39. Yedavalli VS Neuveut C Chi YH Kleiman L Jeang KT Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function Cell 2004, 119(3):381-392. 10.1016/j.cell.2004.09.029 15507209
40. Richter L Bone JR Kuroda MI RNA-dependent association of the Drosophila maleless protein with the male X chromosome Genes Cells 1996, 1(3):325-336. 10.1046/j.1365-2443.1996.26027.x 9133666
41. Elvira G Massie B DesGroseillers L The zinc-finger protein ZFR is critical for Staufen 2 isoform specific nucleocytoplasmic shuttling in neurons J Neurochem 2006, 96(1):105-117. 10.1111/ j.1471-4159.2005.03523.x 16277607
42. Dignam JD Lebovitz RM Roeder RG Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res 1983, 11(5):1475-1489. 325809 6828386 10.1093/nar/ 11.5.1475
43. Herold A Teixeira L Izaurralde E Genome-wide analysis of nuclear mRNA export pathways in Drosophila Embo J 2003, 22(10):2472-2483. 155991 12743041 10.1093/emboj/cdg233
44. Chu F Nusinow DA Chalkley RJ Plath K Panning B Burlingame AL Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry Mol Cell Proteomics 2006, 5(1):194-203. 16210244
45. Straub T Gilfillan GD Maier VK Becker PB The Drosophila MSL complex activates the transcription of target genes Genes Dev 2005, 19(19):2284-2288. 1240036 16204179 10.1101/gad.1343105