Telomere-maintenance mechanisms in soft-tissue malignant fibrous histiocytomas

Journal of Bone and Joint Surgery

Volumn 91, Issue 4, 2009, Pages 928-937

  Matsuo, Toshihiro ^a   Shay, Jerry W ^b   Wright, Woodring E ^b   Hiyama, Eiso ^a   Shimose, Shoji ^a   Kubo, Tadahiko ^a   Sugita, Takashi ^a   Yasunaga, Yuji ^a   Ochi, Mitsuo ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TERT PROTEIN, HUMAN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN TISSUE; LOG RANK TEST; MALE; MALIGNANT FIBROUS HISTIOCYTOMA; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SEX; SOFT TISSUE MALIGNANT FIBROUS HISTIOCYTOMA; TELOMERE; TISSUE PRESERVATION; TUMOR VOLUME; UNIVARIATE ANALYSIS; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOFT TISSUE TUMOR; ULTRASTRUCTURE;

AGED; FEMALE; HISTIOCYTOMA, MALIGNANT FIBROUS; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOFT TISSUE NEOPLASMS; TELOMERASE; TELOMERE;

EID: 65349084875     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/JBJS.G.01390     Document Type: Article

References (52)

1. Zakian VA. Structure and function of telomeres. Annu Rev Genet. 1989;23:579-604.
2. Blackburn EH. Telomerases. Annu Rev Biochem. 1992;61:113-129
3. Levy MZ, Allsopp RC, Futcher AB, Greider CW, Harley CB. Telomere end-replication problem and cell aging. J Mol Biol. 1992;225:951-960
4. Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature. 1990;345:458-460 (Pubitemid 20178256)
5. Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JW. Telomerase activity in human germline and embryonic tissues and cells. Dev Genet. 1996;18:173-179 (Pubitemid 26116862)
6. Martin JA, Buckwalter JA. The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair. J Bone Joint Surg Am. 2003;85 Suppl 2:106-110
7. Yamanishi Y, Hiyama K, Maeda H, Ishioka S, Murakami T, Hiyama E, Kurose Y, Shay JW, Yamakido M. Telomerase activity in rheumatoid synovium correlates with the mononuclear cell infiltration level and disease aggressiveness of rheumatoid arthritis. J Rheumatol. 1998;25:214-220 (Pubitemid 28088245)
8. Schneider-Stock R, Epplen JT, Walter H, Radig K, Rys J, Epplen C, Hoang-Vu C, Niezabitowski A, Roessner A. Telomeric lengths and telomerase activity in liposarcomas. Mol Carcinog. 1999;24:144-151 (Pubitemid 29115917)
9. Aogi K, Woodman A, Urquidi V, Mangham DC, Tarin D, Goodison S. Telomerase activity in soft-tissue and bone sarcomas. Clin Cancer Res. 2000;6:4776-4781 (Pubitemid 32110419)
10. Tomoda R, Seto M, Tsumuki H, Iida K, Yamazaki T, Sonoda J, Matsumine A, Uchida A. Telomerase activity and human telomerase reverse transcriptase mRNA expression are correlated with clinical aggressiveness in soft tissue tumors. Cancer. 2002;95:1127-1133 (Pubitemid 34925366)
11. Yan P, Benhattar J, Coindre JM, Guillou L. Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas. Int J Cancer. 2002;98:851-856 (Pubitemid 34286680)
12. Ulaner GA, Huang HY, Otero J, Zhao Z, Ben-Porat L, Satagopan JM, Gorlick R, Meyers P, Healey JH, Huvos AG, Hoffman AR, Ladanyi M. Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma. Cancer Res. 2003;63:1759-1763 (Pubitemid 36469314)
13. Montgomery E, Argani P, Hicks JL, DeMarzo AM, Meeker AK. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. Am J Pathol. 2004;164:1523-1529 (Pubitemid 38529754)
14. Sanders RP, Drissi R, Billups CA, Daw NC, Valentine MB, Dome JS. Telomerase expression predicts unfavorable outcome in osteosarcoma. J Clin Oncol. 2004;22:3790-3797 (Pubitemid 41095220)
15. Terasaki T, Kyo S, Takakura M, Maida Y, Tsuchiya H, Tomita K, Inoue M. Analysis of telomerase activity and telomere length in bone and soft tissue tumors. Oncol Rep. 2004;11:1307-1311
16. Ulaner GA, Hoffman AR, Otero J, Huang HY, Zhao Z, Mazumdar M, Gorlick R, Meyers P, Healey JH, Ladanyi M. Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas. Genes Chromosomes Cancer. 2004;41:155-162 (Pubitemid 39096741)
17. Umehara N, Ozaki T, Sugihara S, Kunisada T, Morimoto Y, Kawai A, Nishida K, Yoshida A, Murakami T, Inoue H. Influence of telomerase activity on bone and soft tissue tumors. J Cancer Res Clin Oncol. 2004;130:411-416 (Pubitemid 39044344)
18. Henson JD, Hannay JA, McCarthy SW, Royds JA, Yeager TR, Robinson RA, Wharton SB, Jellinek DA, Arbuckle SM, Yoo J, Robinson BG, Learoyd DL, Stalley PD, Bonar SF, Yu D, Pollock RE, Reddel RR. A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clin Cancer Res. 2005;11:217-225 (Pubitemid 40075798)
19. Matsuo T, Sugita T, Shimose S, Kubo T, Yasunaga Y, Hiyama E, Ochi M. Postradiation malignant fibrous histiocytoma and osteosarcoma of a patient with high telomerase activities. Anticancer Res. 2005;25:2951-2955 (Pubitemid 41044684)
20. Matsuo T, Hiyama E, Sugita T, Shimose S, Kubo T, Mochizuki Y, Adachi N, Ochi M. Telomere length and telomerase activity in extra-abdominal desmoid tumors. Anticancer Res. 2007;27:411-415 (Pubitemid 46363361)
21. Matsuo T, Hiyama E, Sugita T, Shimose S, Kubo T, Mochizuki Y, Adachi N, Kojima K, Sharman P, Ochi M. Telomerase activity in giant cell tumors of bone. Ann Surg Oncol. 2007;14:2896-2902 (Pubitemid 47460620)
22. Shay JW, Wright WE. Telomerase: a target for cancer therapeutics. Cancer Cell. 2002;2:257-265
23. Reddel RR. Alternative lengthening of telomeres, telomerase, and cancer. Cancer Lett. 2003;194:155-162 (Pubitemid 36577326)
24. Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med. 1997;3:1271-1274 (Pubitemid 27508830)
25. Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer. 1997;33:787-791 (Pubitemid 127704664)
26. Hiyama E, Yokoyama T, Tatsumoto N, Hiyama K, Imamura Y, Murakami Y, Kodama T, Piatyszek MA, Shay JW, Matsuura Y. Telomerase activity in gastric cancer. Cancer Res. 1995;55:3258-3262
27. Tatsumoto N, Hiyama E, Murakami Y, Imamura Y, Shay JW, Matsuura Y, Yokoyama T. High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer. Clin Cancer Res. 2000;6:2696-2701 (Pubitemid 30482106)
28. Hiyama E, Hiyama K. Clinical utility of telomerase in cancer. Oncogene. 2002;21:643-649
29. Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 1995;14:4240-4248
30. Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 1997;90:785-795 (Pubitemid 27357969)
31. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR. Telomerase catalytic subunit homologs from fission yeast and human. Science. 1997;277:955-959 (Pubitemid 27366681)
32. Nakayama J, Tahara H, Tahara E, Saito M, Ito K, Nakamura H, Nakanishi T, Tahara E, Ide T, Ishikawa F. Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nat Genet. 1998;18:65-68 (Pubitemid 28027882)
33. Guillou L, Coindre JM, Bonichon F, Nguyen BB, Terrier P, Collin F, Vilain MO, Mandard AM, Le Doussal V, Leroux A, Jacquemier J, Duplay H, Sastre-Garau X, Costa J. Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma. J Clin Oncol. 1997;15:350-362 (Pubitemid 27020593)
34. Kawaguchi N, Matumoto S, Manabe J. New method of evaluating the surgical margin and safety margin for musculoskeletal sarcoma, analysed on the basis of 457 surgical cases. J Cancer Res Clin Oncol. 1995;121:555-563
35. Hiyama E, Hiyama K, Yokoyama T, Ichikawa T, Matsuura Y. Length of telomeric repeats in neuroblastoma: correlation with prognosis and other biological characteristics. Jpn J Cancer Res. 1992;83:159-164
36. Grant JD, Broccoli D, Muquit M, Manion FJ, Tisdall J, Ochs MF. Telometric: a tool providing simplified, reproducible measurements of telomeric DNA from constant field agarose gels. Biotechniques. 2001;31:1314-6, 1318. (Pubitemid 33131215)
37. Borden EC, Baker LH, Bell RS, Bramwell V, Demetri GD, Eisenberg BL, Fletcher CD, Fletcher JA, Ladanyi M, Meltzer P, O'Sullivan B, Parkinson DR, Pisters PW, Saxman S, Singer S, Sundaram M, van Oosterom AT, Verweij J, Waalen J, Weiss SW, Brennan MF. Soft tissue sarcomas of adults: state of the translational science. Clin Cancer Res. 2003;9:1941-1956 (Pubitemid 36687613)
38. Perrem K, Bryan TM, Englezou A, Hackl T, Moy EL, Reddel RR. Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids. Oncogene. 1999;18:3383-3390 (Pubitemid 29286984)
39. Scheel C, Schaefer KL, Jauch A, Keller M, Wai D, Brinkschmidt C, van Valen F, Boecker W, Dockhorn-Dworniczak B, Poremba C. Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas. Oncogene. 2001;20:3835-3844 (Pubitemid 32646194)
40. Kirkpatrick KL, Clark G, Ghilchick M, Newbold RF, Mokbel K. hTERT mRNA expression correlates with telomerase activity in human breast cancer. Eur J Surg Oncol. 2003;29:321-326 (Pubitemid 36675686)
41. Hiyama E, Yamaoka H, Matsunaga T, Hayashi Y, Ando H, Suita S, Horie H, Kaneko M, Sasaki F, Hashizume K, Nakagawara A, Ohnuma N, Yokoyama T. High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma. Br J Cancer. 2004;91:972-979 (Pubitemid 39273793)
42. Takakura M, Kyo S, Kanaya T, Tanaka M, Inoue M. Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res. 1998;58:1558-1561 (Pubitemid 28193624)
43. Li H, Zhao LL, Funder JW, Liu JP. Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells. J Biol Chem. 1997;272:16729-16732 (Pubitemid 27289765)
44. Le Doussal V, Coindre JM, Leroux A, Hacene K, Terrier P, Bui NB, Bonichon F, Collin F, Mandard AM, Contesso G. Prognostic factors for patients with localized primary malignant fibrous histiocytoma: a multicenter study of 216 patients with multivariate analysis. Cancer. 1996;77:1823-1830 (Pubitemid 26125182)
45. Kempson RL, Kyriakos M. Fibroxanthosarcoma of the soft tissues. A type of malignant fibrous histiocytoma. Cancer. 1972;29:961-976
46. Weiss SW. Malignant fibrous histiocytoma. A reaffirmation. Am J Surg Pathol. 1982;6:773-784
47. Rööser B, Willén H, Gustafson P, Alvegård TA, Rydholm A. Malignant fibrous histiocytoma of soft tissue. A population-based epidemiologic and prognostic study of 137 patients. Cancer. 1991;67:499-505.
48. Fletcher CD. Pleomorphic malignant fibrous histiocytoma: fact or fiction? A critical reappraisal based on 159 tumors diagnosed as pleomorphic sarcoma. Am J Surg Pathol. 1992;16:213-228
49. Fletcher CD, Gustafson P, Rydholm A, Willén H, Akerman M. Clinicopathologic re-evaluation of 100 malignant fibrous histiocytomas: prognostic relevance of subclassification. J Clin Oncol. 2001;19:3045-3050 (Pubitemid 32565442)
50. Jackson SR, Zhu CH, Paulson V, Watkins L, Dikmen ZG, Gryaznov SM, Wright WE, Shay JW. Antiadhesive effects of GRN163L - an oligonucleotide N3′->P5′ thiophosphoramidate targeting telomerase. Cancer Res. 2007;67:1121-1129 (Pubitemid 46270769)
51. Namba M, Nishitani K, Fukushima F, Kimoto T. Multistep carcinogenesis of normal human fibroblasts. Human fibroblasts immortalized by repeated treatment with Co-60 gamma rays were transformed into tumorigenic cells with Ha-ras oncogenes. Anticancer Res. 1988;8:947-958
52. Girardi AJ, Weinstein D, Moorhead PS. SV40 transformation of human diploid cells. A parallel study of viral and karyologic parameters. Ann Med Exp Biol Fenn. 1966;44:242-254