-
1
-
-
0031010342
-
Survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S. Survey of telomerase activity in human cancer. Eur J Cancer 1997;33:787-91.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
2
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider C, Blackburn E. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985;43:405-13.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.1
Blackburn, E.2
-
3
-
-
0029128798
-
Telomerase and DNA end replication: No longer a lagging strand problem?
-
Lingner J, Cooper J, Cech T. Telomerase and DNA end replication: no longer a lagging strand problem? Science 1995;269:1533-4.
-
(1995)
Science
, vol.269
, pp. 1533-1534
-
-
Lingner, J.1
Cooper, J.2
Cech, T.3
-
4
-
-
0029096515
-
The RNA component of human telomerase
-
Feng J, Funk W, Wang S, et al. The RNA component of human telomerase. Science 1995;269:1236-41.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.2
Wang, S.3
-
5
-
-
19844382620
-
Senescence and immortalization: Role of telomeres and telomerase
-
Shay J, Wright W. Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 2004;26:867-74.
-
(2004)
Carcinogenesis
, vol.26
, pp. 867-874
-
-
Shay, J.1
Wright, W.2
-
6
-
-
0036467499
-
Telomerase regulation: Not just flipping the switch
-
Aisner D, Wright W, Shay J. Telomerase regulation: not just flipping the switch. Curr Opin Genet Dev 2002;13:80-5.
-
(2002)
Curr Opin Genet Dev
, vol.13
, pp. 80-85
-
-
Aisner, D.1
Wright, W.2
Shay, J.3
-
7
-
-
0036362266
-
Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
-
Forsyth N, Wright W, Shay J. Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again. Differentiation 2002;69:188-97.
-
(2002)
Differentiation
, vol.69
, pp. 188-197
-
-
Forsyth, N.1
Wright, W.2
Shay, J.3
-
8
-
-
0043199578
-
Telomerase maintains telomere structure in normal human cells
-
Masutomi K, Yu EY, Khurts S, et al. Telomerase maintains telomere structure in normal human cells. Cell 2003;114:241-53.
-
(2003)
Cell
, vol.114
, pp. 241-253
-
-
Masutomi, K.1
Yu, E.Y.2
Khurts, S.3
-
9
-
-
33645089672
-
Telomerase as a therapeutic target in cancer
-
Gellert G, Jackson S, Dikmen Z, Wright W, Shay J. Telomerase as a therapeutic target in cancer. Drug Discovery Today: Disease Mechanisms 2005;2:159-64.
-
(2005)
Drug Discovery Today: Disease Mechanisms
, vol.2
, pp. 159-164
-
-
Gellert, G.1
Jackson, S.2
Dikmen, Z.3
Wright, W.4
Shay, J.5
-
11
-
-
0037889841
-
Telomere inhibition and telomere disruption as proceses for drug targeting
-
Resler E, Bearss D, Hurley L. Telomere inhibition and telomere disruption as proceses for drug targeting. Annu Rev Pharmacol Toxicol 2003;43:359-79.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 359-379
-
-
Resler, E.1
Bearss, D.2
Hurley, L.3
-
12
-
-
0034839552
-
Telomerase inhibitors- oligonucleotide phosphoramidates as potential therapeutic agents
-
Gryaznov S, Pongracz K, Matray T, et al. Telomerase inhibitors- oligonucleotide phosphoramidates as potential therapeutic agents. Nucleosides Nucleotides Nucleic Acids 2001;20:401-10.
-
(2001)
Nucleosides Nucleotides Nucleic Acids
, vol.20
, pp. 401-410
-
-
Gryaznov, S.1
Pongracz, K.2
Matray, T.3
-
13
-
-
0037148567
-
Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors
-
Herbert B-S, Pongracz K, Shay J, Gryaznov S. Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors. Oncogene 2002;21:638-42.
-
(2002)
Oncogene
, vol.21
, pp. 638-642
-
-
Herbert, B.-S.1
Pongracz, K.2
Shay, J.3
Gryaznov, S.4
-
14
-
-
2442474441
-
Telomeres in dyskeratosis congentia
-
Shay JW, Wright WE. Telomeres in dyskeratosis congentia. Nat Genet 2004;36:437-8.
-
(2004)
Nat Genet
, vol.36
, pp. 437-438
-
-
Shay, J.W.1
Wright, W.E.2
-
15
-
-
0042674370
-
A novel telomerase template antagonist (GRN163) as a potential anticancer agent
-
Asai A, Oshima Y, Yamamoto Y, et al. A novel telomerase template antagonist (GRN163) as a potential anticancer agent. Cancer Res 2003;63:3931-9.
-
(2003)
Cancer Res
, vol.63
, pp. 3931-3939
-
-
Asai, A.1
Oshima, Y.2
Yamamoto, Y.3
-
16
-
-
4344624834
-
Antitumor effects of specific telomerase inhibitor GHN163 in human glioblastoma xenografts
-
Ozawa T, Gryaznov S, Hu L, et al. Antitumor effects of specific telomerase inhibitor GHN163 in human glioblastoma xenografts. Neuro-Oncol 2004;6:218-26.
-
(2004)
Neuro-Oncol
, vol.6
, pp. 218-226
-
-
Ozawa, T.1
Gryaznov, S.2
Hu, L.3
-
17
-
-
0346336773
-
Telomerase inhibition with an oligonucleotide telomerase template antagonist: In vitro and in vivo studies in multiple myeloma and lymphoma
-
Wang ES, Wu K, Chin AC, et al. Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma. Blood 2004;103:258-66.
-
(2004)
Blood
, vol.103
, pp. 258-266
-
-
Wang, E.S.1
Wu, K.2
Chin, A.C.3
-
18
-
-
0037427086
-
hTERT associates with human telomeres and enhances genomic stability and DNA repair
-
Sharma GG, Gupta G, Wang H, et al. hTERT associates with human telomeres and enhances genomic stability and DNA repair. Oncogene 2003;22:131-46.
-
(2003)
Oncogene
, vol.22
, pp. 131-146
-
-
Sharma, G.G.1
Gupta, G.2
Wang, H.3
-
19
-
-
23444453219
-
Lipid modification of GRN163, a N3′→P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition
-
Herbert B-S, Gellert GC, Hochreiter A, et al. Lipid modification of GRN163, a N3′→P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition. Oncogene 2005;24:5262-8.
-
(2005)
Oncogene
, vol.24
, pp. 5262-5268
-
-
Herbert, B.-S.1
Gellert, G.C.2
Hochreiter, A.3
-
20
-
-
30944442508
-
Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma
-
Djojosubroto M, Chin A, Go N, et al. Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma. Hepatology 2005;42:1127-36.
-
(2005)
Hepatology
, vol.42
, pp. 1127-1136
-
-
Djojosubroto, M.1
Chin, A.2
Go, N.3
-
21
-
-
33645244083
-
Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer
-
Gellert G, Dikmen Z, Wright W, Gryaznov S, Shay J. Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer. Breast Cancer Res Treat 2006;96:73-81.
-
(2006)
Breast Cancer Res Treat
, vol.96
, pp. 73-81
-
-
Gellert, G.1
Dikmen, Z.2
Wright, W.3
Gryaznov, S.4
Shay, J.5
-
22
-
-
24744446474
-
In vivo inhibition of lung cancer by GRN163L: A novel human telomerase inhibitor
-
Dikmen ZG, Gellert GC, Jackson S, et al. In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor. Cancer Res 2005;65:7866-73.
-
(2005)
Cancer Res
, vol.65
, pp. 7866-7873
-
-
Dikmen, Z.G.1
Gellert, G.C.2
Jackson, S.3
-
23
-
-
0035217744
-
Telomerase inhibitors for the treatment of cancer: The current perspective
-
Perry P, Arnold J, Jenkins T. Telomerase inhibitors for the treatment of cancer: the current perspective. Expert Opin Investig Drugs 2001;10:2141-56.
-
(2001)
Expert Opin Investig Drugs
, vol.10
, pp. 2141-2156
-
-
Perry, P.1
Arnold, J.2
Jenkins, T.3
-
24
-
-
0141842659
-
Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells
-
Chen Z, Koeneman KS, Corey DR. Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells. Cancer Res 2003;63:5917-25.
-
(2003)
Cancer Res
, vol.63
, pp. 5917-5925
-
-
Chen, Z.1
Koeneman, K.S.2
Corey, D.R.3
-
25
-
-
0033049185
-
Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels
-
Yi X, Tesmer VM, Savre-Train I, Shay JW, Wright WE. Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels. Mol Cell Biol 1999;19:3989-97.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3989-3997
-
-
Yi, X.1
Tesmer, V.M.2
Savre-Train, I.3
Shay, J.W.4
Wright, W.E.5
-
26
-
-
0141954014
-
Effects of oligonucleotide N3′→P5′ thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells
-
Akiyama M, Hideshima T, Shammas MA, et al. Effects of oligonucleotide N3′→P5′ thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells. Cancer Res 2003;63:6187-94.
-
(2003)
Cancer Res
, vol.63
, pp. 6187-6194
-
-
Akiyama, M.1
Hideshima, T.2
Shammas, M.A.3
-
27
-
-
0036850631
-
Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides
-
Dias N, Stein C. Potential roles of antisense oligonucleotides in cancer therapy. The example of Bcl-2 antisense oligonucleotides. Eur J Pharm Biopharm 2002;54:263-9.
-
(2002)
Eur J Pharm Biopharm
, vol.54
, pp. 263-269
-
-
Dias, N.1
Stein, C.2
-
28
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - is the bullet really magical?
-
Stein C, Cheng Y. Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science 1993;261:1004-12.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.1
Cheng, Y.2
-
29
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
Guvakova MA, Yakubov LA, Vlodavsky I, Tonkinson JL, Stein CA. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J Biol Chem 1995;270:2620-7.
-
(1995)
J Biol Chem
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
30
-
-
0029919656
-
Multiple mechanisms may contribute to the cellular antiadhesive effects of phosphorothioate oligodeoxynucleotides
-
Khaled Z, Benimetskaya L, Zeltser R, et al. Multiple mechanisms may contribute to the cellular antiadhesive effects of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res 1996;24:737-45.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 737-745
-
-
Khaled, Z.1
Benimetskaya, L.2
Zeltser, R.3
-
31
-
-
0033786652
-
Fine-needle aspiration cytologic technique for lung cancer has a high potential of malignant cell spread through the tract
-
Sawabata N, Ohta M, Maeda H. Fine-needle aspiration cytologic technique for lung cancer has a high potential of malignant cell spread through the tract. Chest 2000;118:936-9.
-
(2000)
Chest
, vol.118
, pp. 936-939
-
-
Sawabata, N.1
Ohta, M.2
Maeda, H.3
-
33
-
-
0029864898
-
Dissemination of malignant tumors after video-assisted thoracic surgery: A report of twenty-one cases. The video-assisted thoracic surgery study group
-
Downey R, McCormack P. Dissemination of malignant tumors after video-assisted thoracic surgery: a report of twenty-one cases. The video-assisted thoracic surgery study group. J Thorac Cardiovasc Surg 1996;111:954-60.
-
(1996)
J Thorac Cardiovasc Surg
, vol.111
, pp. 954-960
-
-
Downey, R.1
McCormack, P.2
|