Perinatal TCDD exposure and the adult onset of autoimmune disease

Journal of Immunotoxicology

Volumn 5, Issue 4, 2008, Pages 413-418

  Gogal, R M ^a   Holladay, S D ^b  

^a CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

Autoimmune disease; Development; Gestation; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BETA ADRENERGIC RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR;

ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; C57BL 6 MOUSE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL MIGRATION; CELL SELECTION; DEVELOPMENTAL BIOLOGY; DISEASE EXACERBATION; DISEASE PREDISPOSITION; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; NONHUMAN; ONSET AGE; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK ASSESSMENT; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

AGE OF ONSET; ANIMALS; AUTOIMMUNE DISEASES; FEMALE; HUMANS; IMMUNE SYSTEM; LYMPHOPOIESIS; MATERNAL EXPOSURE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; TETRACHLORODIBENZODIOXIN;

MUS; RODENTIA; TETRA;

EID: 65249131750     PISSN: 1547691X     EISSN: 1547691X     Source Type: Journal    
DOI: 10.1080/10408360802483201     Document Type: Article

References (47)

1. Antignac, J. P., Marchand, P., Gade, C., Matayron, G., el Qannari, M., Le Bizec, B. and Andre, F. 2006. Studying variations in the PCDD/PCDF profile across various food products using multivariate statistical analysis. Anal. Bioanal. Chem. 384:271-279.
2. Baccarelli, A., Mocarelli, P., D. G., Patterson, Jr., Bonzini, M., Pesatori, A. C., Caporaso, N. and Landi, M. T. 2002. Immunologic effects of dioxin: New results from Seveso and comparison with other studies. Environ. Health Perspect. 110:1169-1173.
3. Baron, F., Gothot, A., Salmon, J.P., Hermanne, J. P., Pierard, G. E., Fillet, G. and Beguin, Y. 2000. Clinical course and predictive factors for cyclosporine-induced autologous graft-versus-host disease after autologous hematopoietic stem cell transplantation. Br. J. Haematol.111:745-753.
4. Besteman, E. G., Zimmerman, K. L. and Holladay, S. D. 2005. Tetrachlorodibenzo-p-dioxin (TCDD) inhibits differentiation and increases apoptotic cell death of precursor T-cells in fetal mouse thymus. J. Immunotoxicol. 2:107-114.
5. Blaylock, B. L., Ahmed, S. A. and Holladay, S. D. 2005. Prenatal immunotoxicant exposure and autoimmune disease. In: Developmental Immunotoxicology, (S. D., Holladay, Ed.), Boca Raton, FL: CRC Press, pp. 215-228.
6. Blaylock, B. L., Holladay, S. D., Comment, C. E., Heindel, J. J. and Luster, M. I. 1992. Exposure to tetrachlorodibenzo-p-dioxin (TCDD) alters fetal thymocyte maturation. Toxicol. Appl. Pharmacol.112:207-213.
7. Boverhoff, D. R., Tam, E., Harney, A. S., Crawford, R. B., Kaminski, N. E. and Zacharewski, R. 2004. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B-cells. Mol. Pharmacol. 66:1662-1670.
8. Camacho, I. A., Nagarkatti, M. and Nagarkatti, P. S. 2004. Evidence for induction of apoptosis in T-cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol. Sci. 78:96-106.
9. Cariappa, A., Tang, M., Parng, C., Nebelitskiy, E., Carroll, M., Georgopoulos, K. and Pillai, S. 2001. The follicular versus marginal zone B-lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunity 14:603-615.
10. Collins, J. J., Acquavella, J. F. and Friedlander, B. R. 1992. Reconciling old and new findings in dioxin. Epidemiology 3:65-69.
11. DeWaal, E. J., Schuurman, H. J., Loeber, J. G., Van Loveren, H. and Vos, J. G. 1992. Alterations in the cortical thymic epithelium of rats after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): An (immuno)histological study. Toxicol. Appl. Pharmacol. 115:80-88.
12. Dong, L., Ma, Q. and Whitlock, J. P. 1997. Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8- tetrach lorodibenzo-p-dioxin. J. Biol. Chem. 272:29614-29619.
13. Esser, C., Steinwachs, S., Herder, C., Majora, M. and Lai, Z. 2005. Effects of a single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin given at postpuberty, in senescent mice. Toxicol. Lett. 157:89-98.
14. Fingerhut, M.A., Steenland, K., Sweeney, M. H., Halperin, W. E., Piacitelli, L. A. and Marlow, D. A. 1992. Old and new reflections on dioxin. Epidemiology 3:66-72.
15. Fujimoto, M. and Sato, S. 2007. B-Cell signaling and autoimmune diseases: CD19/CD22 loop as a B-cell signaling device to regulate the balance of autoimmunity. J. Dematol. Sci. 46:1-9.
16. Gehrs, B. C. and Smialowicz, R. J. 1999. Persistent suppression of delayedtype hypersensitivity in adult F344 rats after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology 134:79-88.
17. Gehrs, B. C. and Smialowicz, R. J. 1997. Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin: I. Effects on the fetus and the neonate. Toxicology 122:219-228.
18. Gehrs, B. C., Riddle, M. M., Williams, W. C. and Smialowicz, R. J. 1997. Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: II. Effects on the pup and the adult. Toxicology 122:229-240.
19. Hanawa, H., Tsuchida, M., Matsumoto, Y., Watanabe, H., Abo, T., Sekikawa, H., Kodama, M., Zhang, S., Izumi, T. and Shibata, A. 1993. Characterization of T-cells infiltrating the heart in rats with experimental autoimmune myocarditis. Their similarity to extrathymic T-cells in mice and the site of proliferation. J. Immunol.150:5682-5695.
20. Hess, A. D., Fischer, A. C. and Beschorner, W. E. 1990. Effector mechanisms in cyclosporine A-induced syngeneic graft-versus-host disease. Role of CD4+ and CD8+ T lymphocyte subsets. J. Immunol. 145:526-533.
21. Holladay, S. D. 1999. Prenatal immunotoxicant exposure: Increased risk of postnatal autoimmune disease? Environ. Health Perspect.107:687-691.
22. Holladay, S. D. and Luster, M. I. 1996. Alterations in fetal thymic and liver hematopoietic cells as an indicator of exposure to developmental immunotoxicants. Environ. Health Perspect. 104:809-813.
23. Holladay, S. D., Lindstrom, P., Blaylock, B. L., Comment, C. E., Germolec, D. R., Heindel, J. J. and Luster, M. I. 1991. Perinatal thymocyte antigen expression and postnatal immune development altered by exposure to tetrachlorodibenzo-p-dioxin (TCDD). Teratology 44:385-393.
24. Holladay, S.D. and Smialowicz, R.J. 2000. Development of the immune system: Differential effects depending on time of exposure. Environ. Health Perspect 108:463-473.
25. Holsapple, M. P., Snyder, N. K., Wood, S. C. and Morris, D. L. 1991. A review of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: 1991 update. Toxicology 69:219-255.
26. Kakkanaiah, V. N., Pyle, R. H., Nagarkatti, M. and Nagarkatti, P. S. 1990. Evidence for major alterations in the thymocyte subpopulations in murine models of autoimmune diseases. J. Autoimmunity 3:27-28.
27. Kamath, A. B., Xu, H., Nagarkatti, P. S. and Nagarkatti, M. 1997. Evidence for the induction of apoptosis in thymocytes by 2,3,7,8- tetrachlorodi benzo-p-dioxin in vivo. Toxicol. Appl. Pharmacol. 142:367-377.
28. Knutson, J. C. and Poland, A. 1982. Response of murine epidermis to 2,3,7,8-tetrachlorodibenzon-p-dioxin: Interaction of the ah and hr loci. Cell 30:225-234.
29. Kosugi, A., Zuniga-Pflunker, J. C., Sharrow, S. O., Kruisbeek, A. M. and Shearer, G. M. 1989. Effect of cyclosporin A on lymphopoiesis. II. Developmental effects on immature thymocytes in fetal thymus organ culture treated with cyclosporin A. J. Immunol. 143:3134-3140.
30. Kruisbeek, A. M., Bridges, S., Carmen, J., Longo, D. L. and Mond, J. J. 1985. In vivo treatment of neonatal mice with anti-I-A antibodies interferes with the development of the Class I, Class II, and Mls-reactive proliferating T-cell subset. J. Immunol. 134:3597-3604.
31. Martin, F. and Chan, A. C. 2006. B-Cell immunobiology in disease: Evolving concepts from the clinic. Annu. Rev. Immunol. 24:467-496.
32. Mustafa, A., Holladay, S. D., Goff, M., Witonsky, S., Kerr, R., Reilly, C., Sponenberg, P. and R. M., Gogal, Jr. An enhanced postnatal autoimmune profile in 24-week-old C57BL/6 mice developmentally- exposed to TCDD. Toxicol. Appl. Pharmacol. (In press).
33. Neubert, R., Jacob-Muller, U., Stahlmann, R., Helgo, H. and Neubert, D. Polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. 1. Effects on peripheral lymphocyte subpopulation of a non-human primate (Callithrix jacchus) after treatment with 2,3,7,8- tetrachlorodibenzo- p-dioxin (TCDD). Arch. Toxicol.64:345-359.
34. Okuyama, R., Abo, T., Seki, S., Ohteki, T., Sugiura, K., Kusumi, A. and Kumagai, K. 1992. Estrogen administration activates extrathymic T-cell differentiation in the liver. J. Exp. Med. 175:661-669.
35. Reicke, K., Schmidt, A. and Stahlmann, R. 2003. Effects of 2,3,7,8-TCDD and PCB 126 on human thymic epithelial cells in vitro. Arch. Toxicol.77:358-364.
36. Rijhsinghani, A. G., Thompson, K., Bhatia, S. K. and Waldschmidt, T. J. 1996. Estrogen blocks early T-cell development in the thymus. Am. J. Reprod. Immunol. 36:269-277.
37. Roberts, L. 1991. EPA moves to reassess the risk of dioxin. Science252:911.
38. Rocha, B., Bassalli, P. and Guy-Grand, D. 1992. The extrathymic T-cell development pathway. Immunol. Today 13:449-454.
39. Rozman, K. 1989. A critical view of the mechanism(s) of toxicity of 2,3,7,8- tetrachlorodibenzo-p- dioxin. Implications for human safety assessment. Derm. Beruf. Umwelt. 37:81-92.
40. Silverstone, A. E., D. E., Frazier, Jr., and Gasiewicz, T. A. 1994. Alternate immune system targets for TCDD: Lymphocyte stem cells and extrathymic T-cell development. Exp. Clin. Immunogenet. 11:94-101.
41. Silverstone, A. E., Gavalchin, J. and Gasiewicz, T. A. 1998a. TCDD, DES, and estradiol potentiate a lupus-like autoimmune nephritis in NZB × SWR (SNF1) mice. Toxicologist 42:403.
42. Silverstone, A. E., Gavalchin, J., Silvin, C. A., Staples, J. E., Ames, I. H. and Shanley, P. 1998b. Effects of 2,3,7,8-tetrachlorodibenzo-p- dioxin on a murine model of a lupus-like nephritis. Chemosphere18:11-23.
43. Sweeney, M. H. and Mocarelli, P. 2000. Human health effects after exposure to 2,3,7,8-TCDD. Food Add. Contam. 17:303-316.
44. Takahama, Y. 2006. Journey through the thymus: Stromal guides for T-cell development and selection. Nat. Rev. Immunol. 6:127-135.
45. Weber, H. and Birnbaum, L. S. 1985. Dosing with 2,3,7,8- tetrachlorodibenzo- p-dioxin (TCDD) and with 2,3,7,8-tetrachlorodibenzo- p-furan (TCDF) in pregnant C57Bl/6N mice: Distribution and excretion. Arch. Toxicol. 57:159-162.
46. Weisglas-Kuperus, N. T., Sas, C. J., Koopman-Esserboom, C., Van Der Zwan, C. W., De Ridder, M. A., Beishuizen, A., Hooijkaas, H. and Sauer, P. J. 1995. Immunologic effects of background prenatal and postnatal exposure to dioxins and polychlorinated biphenyls in Dutch infants. Pediatr. Res. 38:404-410.
47. Zoller, A. L. and Kersh, G. J. 2006. Estrogen induces thymic atrophy by eliminating early thymic progenitors and inhibiting proliferation of ?-selected thymocytes. J. Immunol. 176:7371-7378.