Persistent suppression of delayed-type hypersensitivity in adult F344 rats after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicology

Volumn 134, Issue 1, 1999, Pages 79-88

  Gehrs, Bradley C ^a   Smialowicz, Ralph J ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; Adult F344 rats; Delayed type hypersensitivity

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BOVINE SERUM ALBUMIN; KEYHOLE LIMPET HEMOCYANIN;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FEMALE; FLOW CYTOMETRY; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PERINATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

ANIMALS; FEMALE; FETUS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYPERSENSITIVITY, DELAYED; MALE; RATS; RATS, INBRED F344; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; TETRACHLORODIBENZODIOXIN;

BOVINAE;

EID: 0033019907     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(99)00024-4     Document Type: Article

References (28)

1. Chang K.J., Hsieh K.H., Lee T.P., Tang S.Y., Tung T.A. Immunologic evaluation of patients with polychlorinated biphenyl poisoning: determination of lymphocyte subpopulations. Toxicol. Appl. Pharmacol. 61:1981;58-63.
2. Cher D.J., Mosmann T.R. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. J. Immunol. 138:1987;3688-3694.
3. Christou N.V., Tellado-Rodriguez J., Chartrand L., Giannas B., Kapadia B., Meakins J., Rode H., Gordon J. Estimating mortality risk in preoperative patients using immunologic, nutritional, and acute-phase response variables. Ann. Surg. 210:1989;69-77.
4. Clark D.A., Gauldie J., Szewczuk M.R., Sweeney G. Enhanced suppressor cell activity as a mechanism of immunosuppression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Exp. Biol. Med. 168:1981;290-299.
5. Cohn J.R., Hohl C.A., Buckley C.E. The relationship between cutaneous cellular immune responsiveness and mortality in a nursing home population. J. Am. Geriatr. Soc. 31:1983;808-809.
6. Cua D.J., Coffman R.L., Stohlman S.A. Exposure to T helper 2 cytokines in vivo before encounter with antigen selects for T helper subsets via alterations in antigen-presenting cell function. J. Immunol. 157:1996;2830-2836.
7. Dieli F., Asherson G.L., Romano G.C., Sireci G., Gervasi F., Salerno A. IL-4 is essential for the systemic transfer of delayed hypersensitivity by T cell lines, role of γ/δ cells. J. Immunol. 152:1994;2698-2704.
8. Evans R.G., Webb K.B., Knutsen A.P., Roodman S.T., Roberts D.W., Bagby J.R., Garrett W.A. Jr., Andrews J.S. A medical follow-up of the health effects of long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Arch. Environ. Health. 43:1988;273-278.
9. Faith R.E., Moore J.A. Impairment of thymus-dependent immune function by exposure of the developing immune system to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). J. Toxicol. Environ. Health. 3:1977;451-464.
10. Fan F., Wierda D., Rozman K.K. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on humoral and cell-mediated immunity in Sprague-Dawley rats. Toxicology. 106:1996;221-228.
11. Fukuma M., Seto Y., Fukushima K., Sakurai T., Dan K., Fujita H., Toyoshima S. The effect of food dye and other environmental substances on the host defense reaction in mice in relation to virus infection. J. Toxicol. Sci. 11:1986;169-177.
12. Gallin J.I. Paul W.E. Fundamental immunology. 3rd ed. 1993;1015-1032 Raven Press, New York.
13. Gehrs B.C., Smialowicz R.J. Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. I. Effects on the fetus and the neonate. Toxicology. 122:1997;219-228.
14. Gehrs B.C., Riddle M.M., Williams W.C., Smialowicz R.J. Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. II. Effects on the pup and the adult. Toxicology. 122:1997;229-240.
15. Hoffman R.E., Stehr-Green P.A., Webb K.B., Evans R.G., Knutsen A.P., Schramm W.F., Staake J.L., Gibson B.B., Steinberg K.K. Health effects of long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Am. Med. Assoc. 255:1986;2031-2038.
16. Holsapple M.P. Immunotoxicity of Halogenated Aromatic Hydrocarbons. Smialowicz R.J., Holsapple M.P. Experimental Immunotoxicology. 1995;265-305 CRC Press, Boca Raton, FL.
17. Huber S.A., Pfaeffle B. Differential Th1 and Th2 cell responses in male and female BALB/c mice infected with Coxsackievirus group B type 3. J. Virol. 68:1994;5126-5132.
18. Jeevan A., Gilliam K., Heard H., Kripke M.L. Effects of ultraviolet radiation on the pathogenesis of Mycobacterium lepraemurium infection in mice. Exp. Dermatol. 1:1992;152-160.
19. Kniker W.T., Lesourd B.M., McBryde J.L., Corriel R.N. Cell-mediated immunity assessed by Multitest CMI skin testing in infants and preschool children. Am. J. Dis. Child. 139:1985;840-845.
20. Knutsen A.P., Roodman S.T., Evans R.G., Mueller K.R., Webb K.B., Stehr-Green P., Hoffman R.E., Schramm W.F. Immune studies in dioxin-exposed Missouri residents: quail run. Bull. Environ. Contam. Toxicol. 39:1987;481-489.
21. Li L., Elliott J.F., Mosmann T.R. IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity. J. Immunol. 153:1994;3967-3978.
22. Lundberg K., Dencker L., Grönvik K.-O. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the specific immune response to ovalbumin in the mouse. Chemosphere. 25:1992;111-114.
23. Moesgaard F., Lykkegaard-Nielsen M., Norgaard-Larsen P., Christophersen S., Mosbech H. Cell-mediated immunity assessed by skin testing (Multitest). I. Normal values in healthy Danish adults. Allergy. 42:1987;591-596.
24. Ross P.S., De Swart R.L., Reijnders P.J.H., Van Loveren H., Vos J.G., Osterhaus A.D.M.E. Contaminant-related suppression of delayed-type hypersensitivity and antibody responses in harbor seals fed herring for the Baltic Sea. Environ. Health Perspect. 103:1995;162-167.
25. RS/1, 1988. RS/1 Release 4. BBN Software Products Corp., Cambridge, MA.
26. Thomas P.T., Hinsdill R.D. The effect of perinatal exposure to tetrachlorodibenzo-p-dioxin on the immune response of young mice. Drug Chem. Toxicol. 2:1979;77-98.
27. Vos J.G., Moore J.A., Zinkl J.G. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the immune system of laboratory animals. Environ. Health Perspect. 5:1973;149-162.
28. Wolf N., Karmaus W. Effects of inhalative exposure to dioxins in wood preservatives on cell-mediated immunity in day-care center teachers. Environ. Res. 68:1995;96-105.