Evidence for induction of apoptosis in T cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Toxicological Sciences

Volumn 78, Issue 1, 2004, Pages 96-106

  Camacho, Iris A ^a   Nagarkatti, Mitzi ^a   Nagarkatti, Prakash S ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Immunotoxicity; Perinatal exposure; TCDD; Thymus

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BIOCHEMICAL MARKER; CASPASE 3; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; DEATH RECEPTOR 5; FAS ANTIGEN; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL DEATH; COLOR; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME DEGRADATION; EVIDENCE BASED MEDICINE; FEMALE; FETUS; FETUS CELL; GESTATIONAL AGE; IMMUNOPHENOTYPING; IMMUNOTOXICITY; IN VITRO STUDY; INVOLUTION; MOUSE; MOUSE STRAIN; NONHUMAN; PERINATAL PERIOD; PREGNANCY; PRENATAL DRUG EXPOSURE; STAINING; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; THYMUS ATROPHY;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; PHENOTYPE; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TERATOGENS; TETRACHLORODIBENZODIOXIN; THYMUS GLAND;

MURINAE;

EID: 1542686218     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh048     Document Type: Article

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