Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties: A study with Chinese Spring deletion lines

BMC Plant Biology

Volumn 9, Issue , 2009, Pages

  Van Den Broeck, Hetty C ^a   Van Herpen, Teun W J M ^a,b   Schuit, Cees ^a   Salentijn, Elma M J ^a   Dekking, Liesbeth ^c,d   Bosch, Dirk ^a   Hamer, Rob J ^a   Smulders, Marinus J M ^a,b   Gilissen, Ludovicus J W J ^a,b   Van Der Meer, Ingrid M ^a,b  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b Allergy Consortium Wageningen ^*  (Norway)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

TRITICUM AESTIVUM;

EPITOPE; GLUTEN; MONOCLONAL ANTIBODY;

ARTICLE; BREAD; CELIAC DISEASE; CHEMISTRY; FLOUR; GENE DELETION; GENETICS; HUMAN; IMMUNOLOGY; PLANT GENE; PROTEIN DATABASE; WHEAT;

ANTIBODIES, MONOCLONAL; BREAD; CELIAC DISEASE; DATABASES, PROTEIN; EPITOPES, T-LYMPHOCYTE; FLOUR; GENE DELETION; GENES, PLANT; GLUTENS; HUMANS; TRITICUM;

EID: 65249126893     PISSN: None     EISSN: 14712229     Source Type: Journal    
DOI: 10.1186/1471-2229-9-41     Document Type: Article

References (66)

1. The molecular basis of celiac disease. F Koning, J Mol Recognit 2003 16 333 336 10.1002/jmr.641 14523946 (Pubitemid 37231702)
2. The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides. W Vader Y Kooy P van Veelen A de Ru D Harris W Benckhuijsen S Pẽa L Mearin JW Drijfhout F Koning, Gastroenterology 2002 122 1729 1737 10.1053/gast.2002.33606 12055577 (Pubitemid 34651415)
3. Structural and genetical studies on the high-molecular-weight subunits of wheat glutenin. P Payne L Holt C Law, Theor Appl Genet 1981 60 229 236 10.1007/BF02342544
4. Characterization of high molecular-weight gliadin and low-molecular-weight glutenin subunits of wheat endosperm by two-dimensional electrophoresis and the chromosomal localization of their controlling genes. EA Jackson LM Holt PI Payne, Theor Appl Genet 1983 66 29 37
5. Starch gel electrophoresis of wheat gluten proteins with concentrated urea. JH Woychik JA Boundy RJ Dimler, Arch Biochem Biophys 1961 94 477 482 10.1016/0003-9861(61)90075-3 13786728
6. Coeliac disease: Dissecting a complex inflammatory disorder. LM Sollid, Nat Rev Immunol 2002 2 647 655 10.1038/nri885 12209133 (Pubitemid 37328722)
7. The intestinal T-cell response to -gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase. H Arentz-Hansen R Korner Molberg H Quarsten W Vader Y Kooy KEA Lundin F Koning P Roepstorff LM Sollid SN McAdam, J Exp Med 2000 191 603 612 10684852 10.1084/jem.191.4.603
8. Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues. H Arentz-Hansen SN McAdam Molberg B Fleckenstein KEA Lundin TJD Jorgensen G Jung P Roepstorff LM Sollid, Gastroenterology 2002 123 803 809 10.1053/gast.2002.35381 12198706
9. Characterization of cereal toxicity for celiac disease patients based on protein homology in grains. LW Vader DT Stepniak EM Bunnik YMC Kooy W de Haan JW Drijfhout PA van Veelen F Koning, Gastroenterology 2003 125 1105 1113 10.1016/S0016-5085(03)01204-6 14517794 (Pubitemid 37193457)
10. Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease.Molberg NES Flæte T Jensen KEA Lundin H Arentz-Hansen OD Anderson AK Uhlen LM Sollid, Gastroenterology 2003 125 337 344 10.1016/S0016-5085(03) 00890-4 12891534 (Pubitemid 36929413)
11. No harm from five year ingestion of oats in coeliac disease. EK Janatuinen TA Kemppainen RJK Julkunen VM Kosma M Maki M Heikkinen MIJ Uusitupa, Gut 2002 50 332 335 11839710 10.1136/gut.50.3.332 (Pubitemid 34161047)
12. Systemic autoimmune disorders in celiac disease. A Fasano, Curr Opin Gastroenterol 2006 22 6 674 679 10.1097/01.mog.0000245543.72537.9e 17053448 (Pubitemid 44624537)
13. Epidemic of coeliac disease in Swedish children. A Ivarsson LA Persson L Nystrom H Ascher B Cavell L Danielsson A Dannaeus T Lindberg B Lindquist L Stenhammar O Hernell, Acta Paediatr 2000 89 165 171 10.1080/080352500750028771 10709885 (Pubitemid 30339587)
14. Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. A Ventura G Magazz L Greco, Gastroenterology 1999 117 297 303 10.1053/gast.1999.0029900297 10419909 (Pubitemid 29352936)
15. Chemistry of gluten proteins. H Wieser, Food Microbiol 2007 24 115 119 10.1016/j.fm.2006.07.004 17008153 (Pubitemid 44428081)
16. Biochemical basis of flour properties in bread wheats. I. Effects of variation in the quantity and size distribution of polymeric protein. RB Gupta K Khan F Macritchie, J Cereal Sci 1993 18 23 41 10.1006/jcrs.1993.1031
17. Biochemical basis of flour properties in bread wheats.II. Changes in polymeric protein-formation and dough/gluten properties associated with the loss of low M R or high M R glutenin subunits. RB Gupta Y Popineau J Lefebvre M Cornec GJ Lawrence F Macritchie, J Cereal Sci 1995 21 103 116 10.1016/0733-5210(95)90026-8
18. Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes. TWJM van Herpen SV Goryunova J van der Schoot M Mitreva EMJ Salentijn O Vorst MF Schenk PA van Veelen F Koning LJM van Soest B Vosman D Bosch RJ Hamer LJWJ Gilissen MJM Smulders, BMC Genomics 2006 7 1 16403227 10.1186/1471-2164-7-1 (Pubitemid 43263150)
19. DNA restriction-fragment variation in the gene family encoding high molecular weight (HMW) glutenin subunits of wheat. NP Harberd D Bartels RD Thompson, Biochem Genet 1986 24 579 596 10.1007/BF00504336 3019303
20. Linkage mapping of genes-controlling endosperm storage proteins in wheat.1. Genes on the short arms of group-1 chromosomes. NK Singh KW Shepherd, Theor Appl Genet 1988 75 628 641 10.1007/BF00289132
21. Molecular genetic maps of the group 6 chromosomes of hexaploid wheat (Triticum aestivum L. em. Thell.). CL Marino NA Tuleen GE Hart JC Nelson ME Sorrells YH Lu P Leroy CR Lopes, Genome 1996 39 359 366 10.1139/g96-046 18469899 (Pubitemid 126529668)
22. The deletion stocks of common wheat. TR Endo BS Gill, J Hered 1996 87 295 307 (Pubitemid 26284618)
23. Molecular characterization of a set of wheat deletion stocks for use in chromosome bin mapping of ESTs. L Qi B Echalier B Friebe B Gill, Funct Integr Genomics 2003 3 39 55 12590342 (Pubitemid 41449143)
24. Standard karyotype and nomenclature system for description of chromosome bands and structural aberrations in wheat (Triticum aestivum). BS Gill B Friebe TR Endo, Genome 1991 34 830 839
25. Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for coeliac disease. C Mitea R Havenaar JW Drijfhout L Edens L Dekking F Koning, Gut 2008 57 25 32 10.1136/gut.2006.111609 17494108
26. A novel and sensitive method for the detection of T cell stimulatory epitopes of /- and -gliadin. EHA Spaenij-Dekking EMC Kooy-Winkelaar WF Nieuwenhuizen JW Drijfhout F Koning, Gut 2004 53 1267 1273 15306583 10.1136/gut.2003.037952 (Pubitemid 39120110)
27. Natural Variation in Toxicity of Wheat: Potential for Selection of Nontoxic Varieties for Celiac Disease Patients. L Spaenij-Dekking Y Kooy-Winkelaar P van Veelen JW Drijfhout H Jonker L van Soest MJM Smulders D Bosch LJWJ Gilissen F Koning, Gastroenterology 2005 129 797 806 10.1053/j.gastro.2005.06.017 16143119 (Pubitemid 41242672)
28. A model for the molecular structure of the glutenins from wheat flour. A Graveland P Bosveld WJ Lichtendonk JP Marseille HHE Moonen A Scheepstra, J Cereal Sci 1985 21 117 126
29. Extraction and fractionation of wheat flour proteins. A Graveland P Bosveld WJ Lichtendonk HHE Moonen A Scheepstra, J Sci Food Agric 1982 33 1117 1128 10.1002/jsfa.2740331109
30. Depolymerisation and re-polymerisation of wheat glutenin during dough processing. I. Relationships between glutenin macropolymer content and quality parameters. PL Weegels AM van de Pijpekamp A Graveland RJ Hamer JD Schofield, J Cereal Sci 1996 23 103 111 10.1006/jcrs.1996.0010 (Pubitemid 126354559)
31. Heat stress and genotype affect the glutenin particles of the glutenin macropolymer-gel fraction. C Don G Lookhart H Naeem F MacRitchie RJ Hamer, J Cereal Sci 2005 42 69 80 10.1016/j.jcs.2005.01.005 (Pubitemid 40717562)
32. R Lásztity, The Chemistry of cereal proteins Boca Raton: Taylor & Francis Ltd 1995
33. The impact of water-soluble pentosans on dough properties. WJ Lichtendonk M Kelfkens R Orsel ACAPA Bekkers JJ Plijter, Wheat Gluten. Proceedings of the Seventh International Gluten Workshop: 2-6 April; Bristol, UK Cambridge: Royal Society of Chemistry, Shewry PR, Tatham AS, 2000 512 518
34. Mapping of gluten T-cell epitopes in the bread wheat ancestors: Implications for celiac disease.Molberg AK Uhlen T Jensen NES Flæte B Fleckenstein H Arentz-Hansen M Raki KEA Lundin LM Sollid, Gastroenterology 2005 128 393 401 10.1053/j.gastro.2004.11.003 15685550 (Pubitemid 40431091)
35. Tetraploid and hexaploid wheat varieties reveal large differences in expression of alpha-gliadins from homoeologous Gli-2 loci. EMJ Salentijn SV Goryunova N Bas IM van der Meer HC van den Broeck T Bastien LJWJ Gilissen MJM Smulders, BMC Genomics 2009 10 48 19171027 10.1186/1471-2164-10-48
36. Characterisation of a -gliadin gene in Triticum tauschii. ME Hassani MR Shariflou MC Gianibelli PJ Sharp, J Cereal Sci 2008 47 59 67 10.1016/j.jcs.2007.01.008 (Pubitemid 350102003)
37. Efficiency and limitations of immunochemical assays for the testing of gluten-free foods. S Denery-Papini Y Nicolas Y Popineau, J Cereal Sci 1999 30 121 131 10.1006/jcrs.1999.0268 (Pubitemid 129533101)
38. Studies in vivo of omega-gliadins in gluten sensitivity (coeliac sprue disease). A Ensari MN Marsh KJ Moriarty CM Moore RJ Fido AS Tatham, Clin Sci 1998 95 419 424 10.1042/CS19980129 9748417 (Pubitemid 28474727)
39. Genomic organization of the complex -gliadin gene loci in wheat. YQ Gu C Crossman X Kong M Luo FM You D Coleman-Derr J Dubcovsky OD Anderson, Theor Appl Genet 2004 109 648 657 10.1007/s00122-004-1672-2 15103408 (Pubitemid 39138795)
40. The prolamin storage proteins of cereal seeds - Structure and evolution. PR Shewry AS Tatham, Biochem J 1990 267 1 12 2183790 (Pubitemid 20122626)
41. Linking glutenin particles to HMW subunit composition. C Don G Mann F Bekes R Hamer, The Gluten Proteins. Proceedings of the 8th International Gluten Workshop: 8-10 September; Viterbo, Italy Cambridge: Royal Society of Chemistry, Lafiandra D, Masci S, D'Ovidio R, 2003 188 192
42. The relationship between HMW glutenin subunit composition and the bread-making quality of British-grown wheat varieties. PI Payne MA Nightingale AF Krattiger LM Holt, J Sci Food Agric 1987 40 51 65 10.1002/jsfa.2740400108
43. New data supporting high M r glutenin subunit 5 as the determinant of quality differences among the pairs 5 + 10 vs. 2 + 12. D Lafiandra R D'Ovidio E Porceddu B Margiotta G Colaprico, J Cereal Sci 1993 18 197 205 10.1006/jcrs.1993.1046
44. Influence of high M r glutenin subunits on glutenin polymers and rheological properties of glutens and gluten subfractions of near-isogenic lines of wheat Sicco. Y Popineau M Cornec J Lefebvre B Marchylo, J Cereal Sci 1994 19 231 241 10.1006/jcrs.1994.1030
45. Genetic diversity of wheat storage proteins and bread wheat quality. G Branlard M Dardevet R Saccomano F Lagoutte J Gourdon, Euphytica 2001 119 59 67 10.1023/A:1017586220359 (Pubitemid 32632240)
46. Revision of the estimates of glutenin gene effects at the Glu-B1 locus from southern Australian wheat breeding programs. HA Eagles RF Eastwood GJ Hollamby EM Martin GB Cornish, Aust J Agric Res 2004 55 1093 1096 10.1071/AR04113 (Pubitemid 39569014)
47. Influence of specific gliadins on the breadmaking quality of wheat. HJ Van lonkhuijsen RJ Hamer C Schreuder, Cereal Chem 1992 69 174 177
48. Inheritance of B subunits of glutenin and - and -gliadins in tetraploid wheats. CY Liu KW Shepherd, Theor Appl Genet 1995 90 1149 1157 10.1007/BF00222936
49. Recombination mapping of some chromosome 1A-, 1B-, 1D- and 6B-controlled gliadins and low-molecular-weight glutenin subunits in common wheat. EV Metakovsky G Branlard VM Chernakov VP Upelniek R Redaelli NE Pogna, Theor Appl Genet 1997 94 788 795 10.1007/s001220050479 (Pubitemid 27253561)
50. Linkage relationships between prolamin genes on chromosomes 1A and 1B of durum wheat. M Ruiz JM Carrillo, Theor Appl Genet 1993 87 353 360 10.1007/BF01184923 (Pubitemid 2013664)
51. Characterization of low-molecular-weight glutenin subunits in durum-wheat by reversed-phase high-performance liquid-chromatography and N-terminal sequencing. S Masci EJL Lew D Lafiandra E Porceddu DD Kasarda, Cereal Chem 1995 72 100 104
52. Characterization of a low-molecular-weight glutenin subunit gene from bread wheat and the corresponding protein that represents a major subunit of the glutenin polymer. S Masci R D'Ovidio D Lafiandra DD Kasarda, Plant Physiol 1998 118 1147 1158 9847089 10.1104/pp.118.4.1147 (Pubitemid 128653050)
53. Evidence for the presence of only one cysteine residue in the D-type low molecular weight subunits of wheat glutenin. S Masci TA Egorov C Ronchi DD Kuzmicky DD Kasarda D Lafiandra, J Cereal Sci 1999 29 17 25 10.1006/jcrs.1998. 0224 (Pubitemid 129550013)
54. D-glutenin subunits - N-terminal squences and evidence for the presence of cysteine. S Masci D Lafiandra E Porceddu EJL Lew HP Tao DD Kasarda, Cereal Chem 1993 70 581 585
55. Characterization of wheat with strongly reduced -gliadin content. H Wieser P Koehler A Folck D Becker, Proceedings of the 9th International Gluten Workshop, Gluten Proteins: 14-16 September; San Francisco, USA AACC International, Lookhart GL, Ng PKW, 2007 13 16
56. Silencing of -gliadins by RNA interference (RNAi) in bread wheat. J Gil-Humanes F Pistn A Hernando JB Alvarez PR Shewry F Barro, J Cereal Sci 2008 48 565 568 10.1016/j.jcs.2008.03.005
57. Innovative approach to low-level gluten determination in foods using a novel sandwich enzyme-linked immunosorbent assay protocol. I Valdés E García M Llorente E Méndez, Eur J Gastroen Hepat 2003 15 465 474 10.1097/00042737-200305000-00002 (Pubitemid 36571036)
58. Correlations of the amount of gluten protein types to the technological properties of wheat flours determined on a micro-scale. H Wieser R Kieffer, J Cereal Sci 2001 34 19 27 10.1006/jcrs.2000.0385 (Pubitemid 32706807)
59. HMW-GS affect the properties of glutenin particles in GMP and thus flour quality. C Don G Mann F Bekes RJ Hamer, J Cereal Sci 2006 44 127 136 10.1016/j.jcs.2006.02.005 (Pubitemid 44189779)
60. Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome. C Mitea Y Kooy-Winkelaar P van Veelen A de Ru JW Drijfhout F Koning L Dekking, Am J Clin Nutr 2008 88 1057 1066 18842794
61. A modified extraction protocol enables detection and quantification of celiac disease-related gluten proteins from wheat. HC Van den Broeck AHP America MJM Smulders D Bosch RJ Hamer LJWJ Gilissen IM van der Meer, J Chrom B 2009 877 975 982 10.1016/j.jchromb.2009.02.035
62. Improvement and simplification of low-background silver staining of proteins by using sodium dithionite. T Rabilloud G Carpentier P Tarroux, Electrophoresis 1988 9 288 291 10.1002/elps.1150090608 2466660 (Pubitemid 18152750)
63. Changes in synthesis and localization of members of the 70-kDa class of heat-shock proteins accompany the induction of embryogenesis in Brassica napus L. microspores. JHG Cordewener G Hause E Görgen R Busink B Hause HJM Dons AAM Van Lammeren MM van Lookeren Campagne P Pechan, Planta 1995 196 747 755 10.1007/BF01106770
64. Rapid ecologically acceptable method for wheat protein content determination - Comparison of methods. B Sebecic J Balenovic, Deut Lebensm-Rundsch 2001 97 221 225 (Pubitemid 33583306)
65. Interaction of water unextractable solids and xylanase with gluten protein: effect of wheat cultivar. MW Wang T van Vliet RJ Hamer, J Cereal Sci 2005 41 251 258 10.1016/j.jcs.2004.07.007 (Pubitemid 40406244)
66. PR Shewry GL Lookhart, Wheat gluten protein analysis St. Paul, MN, USA: AACC International 2003