Drug permeability assay using microhole-trapped cells in a microfluidic device

Analytical Chemistry

Volumn 81, Issue 5, 2009, Pages 1944-1951

  Yeon, Ju Hun ^a   Park, Je Kyun ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TESTING; BLOOD CIRCULATIONS; CELL DAMAGES; CELL TRAPPING; DELIVERY PATHS; DRUG CANDIDATES; DRUG DISCOVERIES; HUMAN INTESTINES; HUMAN SUBJECTS; IN-VIVO; INTESTINAL EPITHELIAL CELLS; LOW PERMEABILITIES; MATHEMATICAL SIMULATIONS; MICRO HOLES; MICRO-FLUIDIC DEVICES; MICROFLUIDIC ASSAYS; MIXING CHANNELS; MOLDING TECHNIQUES; OPTIMAL CONDITIONS; P VALUES; POLYDIMETHYLSILOXANE PDMS;

ASSAYS; CARDIOVASCULAR SYSTEM; CELL MEMBRANES; CYTOLOGY; FLUIDIC DEVICES; MICROCHANNELS; SILICONES;

CAPILLARITY;

DIMETICONE;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; DRUG PENETRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MATHEMATICAL ANALYSIS; MICROFLUIDIC ANALYSIS; NONHUMAN; RAT;

ANIMALS; CACO-2 CELLS; CELLS; DIMETHYLPOLYSILOXANES; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; RATS;

EID: 64749108520     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac802351w     Document Type: Article

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