Predicting human intestinal permeability using single-pass intestinal perfusion to rat

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 10, Issue 3, 2007, Pages 368-379

  Zakeri Milani, Parvin ^a,b   Valizadeh, Hadi ^a,b   Tajerzadeh, Hosnieh ^c   Azarmi, Yadollah ^a   Islambolchilar, Ziba ^a   Barzegar, Saeed ^a   Barzegar Jalali, Mohammad ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ATENOLOL; CARBAMAZEPINE; CEFALEXIN; CIMETIDINE; FUROSEMIDE; HYDROCHLOROTHIAZIDE; IBUPROFEN; KETOPROFEN; METHYLDOPA; METOPROLOL; NAPROXEN; PHENAZONE; PHENOLSULFONPHTHALEIN; PHOSPHATE BUFFERED SALINE; PIROXICAM; PROPRANOLOL; RANITIDINE; WATER;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ABSORPTION; DRUG DETERMINATION; DRUG PENETRATION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; JEJUNUM; MALE; NONHUMAN; PREDICTION; RAT; RELIABILITY; ANIMAL; DRUG STABILITY; FORECASTING; INTESTINE ABSORPTION; METABOLISM; METHODOLOGY; MOLECULAR WEIGHT; ORAL DRUG ADMINISTRATION; PERFUSION; PERMEABILITY; PHARMACOKINETICS; REPRODUCIBILITY; SPECIES DIFFERENCE; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FORECASTING; HUMANS; INTESTINAL ABSORPTION; JEJUNUM; MALE; MOLECULAR WEIGHT; PERFUSION; PERMEABILITY; PHARMACOKINETICS; PHENOLSULFONPHTHALEIN; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SPECIES SPECIFICITY;

EID: 34848857371     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. D. R. Friend, Drug Delivery to the Small Intestine, Current Gastroenterology Reports, 6: 371-376, 2004.
2. G. L. Amidon, A. E. Merfeld, J. B. Dressman. Concentration and pH dependency of amethyldopa absorption in rat intestine. J Pharm Pharmacol, 38: 363-368, 1986.
3. 14C in rats. Chem Pharm Bull (Tokyo), 21: 2031-2038, 1973.
4. T. Cercos-Fortea, A. Polache, A. Nacher, E. Cejudo-Ferragud, V. G. Casabo, M. Merino. Influence of leucine on intestinal baclofen absorption as a model-compound of neutral α-amino acids. Biopharm Drug Dispos, 16: 563-577, 1995.
5. A. Tsuji. Intestinal absorption of β-lactam antibiotics; In M. D. Taylor and G. L. Amidon (eds.), Peptide-based drug design, American Chemical Society, Washington, DC, 299-316, 1995.
6. G.L. Amidon, P.J. Sinko, D. Fleisher. Estimating humah oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds. Pharm Res, 5:651-654, 1988.
7. P. Artursson, J. Karlsson. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial cells. Biochem Biophys Res Commun, 175:880-885, 1991.
8. T.J. Cook, S.S. Shenoy. Intestinal permeability of chlorpyrifos using a single-pass intestinal perfusion method in the rat. Toxicology, 184:125-133, 2003.
9. K.M. Hillgren, A. Kato, R.T Borechard. In vitro systems for studying intestinal drug absorption. Med Res Rev, 15:83-109, 1995.
10. W. Rubas, N. Jezyk, G.M. Grass. Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabit, monkey and dog intestine and human drug absorption. Pharm Res, 10: 113-118, 1993.
11. L. Salphati, K. Childers, L. Pan, K. Tsutsui, L. Takahashi. Evaluation of a single-pass intestinal-perfusion method in rat for the prediction of absorption in man. J Pharm Pharmacol, 53:1007-1013, 2001.
12. W. Crouthamel, A.C.E. Sarapu. Animal models for oral drug delivery in man. American Pharm Assoc, Washington DC, p. 27, 1983.
13. S.C. Sutton, M.T.S. Rinaldi, K.E. Vukovinsky. Comparison of the Gravimetric, Phenol Red, and 14C-PEG-3350 Methods to Determine Water Absorption in the Rat Single-Pass Intestinal Perfusion Model. AAPS PharmSci (http://www,pharmsci.org), 3, 2001.
14. M.L.Hogerle, D. Winne. Drug absorption by the rat jejunum in situ. Dissociation from the ph-partition theory and role of microclimate pH and unstirred layer. Naunyn Schmiedebergs Arch Pharmacol, 322:249-255, 1983.
15. U. Fagerholm, M. Johansson, H. Lennemas. Comparison between permeability coefficients in rat and human jejunum. Pharm Res, 13:1336-1342, 1996.
16. F.D. Gorham. The factor of dilution in gastric analysis. J Amer Med Ass, 81:1735-1742, 1923.
17. U.S.H. Sevensson. High in situ rat intestinal permeability of artemisinin unaffected by multiple dosing and with no evidence of P-gp involvement. Drug Metab Dispos, 27:227-232, 1999.
18. P.J. Sinko, P. Hu, A.P. Waclawski, N.R. Patel. Oral absorption of anti-AIDS nucleoside analogues. 1. Intestinal transport of didanosine in rat and rabbit preparations. J Pharm. Sci, 84:959-965, 1995.
19. D. Ernest, E.D. Alfert, M. Brenda, B.M. Cross, A.A.E. Mcwilliam. CCAC, Guide to the care and use of experimental animals, Canadian Council on Animal Care. vol1, 1993.
20. P. Zakeri.-Milani., M. Barzegar-Jalali, H. Tajerzadeh, Y. Azarmi, H. Valizadeh. Simultaneous determination of naproxen, ketoprofen and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation. J Pharm Biomed Anal, 39:624-630, 2005.
21. H. Valizadeh , P. Zakeri-Milani, Z. Islambulchilar, H. Tajerzadeh. A simple and rapid HPLC method for determining Furosemide, Hydrochlorothiazide and Phenol red: Applicability to Intestinal permeability studies. J AOAC Int, 89:1-6, 2005.
22. P. Zakeri-Milani, H. Valizadeh, Y. Azarmi, M. Barzegar-Jalali, H. Tajerzadeh. Simultaneous determination of metoprolol, propranolol and phenol red in samples from rat in situ intestinal perfusion studies, Daru. 14:102-108, 2006.
23. S. Dadashzadeh, A.M. Vali, N. Rezagholi. LC determination of Piroxicam in human plasma. J Pharm Biomed Anal, 28:1201-4, 2002.
24. P. Modamio, C.F. Lastra, J. Maritto. Error structure for the HPLC analysis for atenolol, metoprolol and propranolol: a useful weighting method in parameter estimation. J Pharm Biomed Anal, 17:507-13, 1998.
25. L.E. Raid, R.J. Sawchuk. Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography. Clin Chem, 37:1863-1866, 1988.
26. E. S. Swenson, B. William, B. Malison, W Curatolo. Intestinal permeability enhancement: Efficacy, Acute local toxicity and reversibility. Pharm Res, 11:1132-42, 1994.
27. P.G. Welling, A. Selen, J.G. Pearson, F. Kwok, M.C. Rogge, A. Ifan, D. Marrero, W.A. Craig, C.A. Johnson. A pharmacokinetic comparison of cephalexin and cefadroxil using HPLC assay procedures. J Biopharm Drug Dispos, 6:147-57, 1985.
28. C.A. Phillips, B.B. Michniak. Transdermal delivery of drugs with differing lipophilicities using azone analogs as dermal penetration enhancers. J Pharm Sci, 84:1427-1433, 1995.
29. I. Komiya, J.Y. Park, A. Kamani, N.F.H. Ho, W.I. Higuchi. Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes. Int J Pharm, 4:249-262, 1980.
30. M.D. Levitt, J.M. Kneip, D.G. Levitt. Use of laminar flow and unstirred layer models to predict intestinal absorption in the rat. J. Clin. Invest., 81:1365-1369, 1988.
31. L.D. Fisher, G. Van Belle. Association and prediction: Linear models with one predictor variable. In: Biostatistics, a-methodology for the health science, Wiley-Interscience, new York, pp. 345-417, 1993.
32. H. Yuasa, K. Matsuda, J. Watanabe. Influence of anaesthetic regimens on intestinal absorption in rats. Pharm Res, 10:884-888, 1993.
33. A. Lindahl, E. Krondhal, A. Gruden, A. Ungell, H. Lennemas. Is the jejunal permeability in rats age-dependent? Pharm Res, 14:1278-1281, 1997.
34. W.L. Chiou, A. Barve. Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats. Pharm Res, 15:1792-1795, 1998.
35. H. Lennernas. Human intestinal permeability. J Pharm Sci, 87:403-410, 1998.
36. N.A. Kasim, M. Whitehouse, C. Ramachandran, M. Bermejo, H. Lennernas, A.S. Hussain, H.E. Junginger, S.A. Stavchansky, K.K. Midha, V.P. Shah, G.L. Amidon. Molecular properties of WHO essential drugs and provisional biopharmaceutical classification. Molecular Pharmaceutics, 1:85-96, 2003.
37. J.D. Irvine, L. Takahashi, K. Lockhart, J. Cheong, J.W. Tolan, H.E. Selick, J.R. Grove. MDCK cells: A tool for membrane permeability screening. J Pharm Sci, 88:28-33, 1998.
38. P. Stenberg, U. Norinder, K. Luthman, P. Artursson. Experimental and computational screening models for the prediction of intestinal drug absorption. J Med Chem, 44:1927-1037, 2001.
39. E. Walker, S. Janich, B.J. Roessler, J.M. Hilfinger, G.L. Amidon. HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: In vitro- in vivo correlation with permeability data from rats and humans. J Pharm Sci, 85:1070-1076, 1996.
40. J.B. Dressman, G.L. Amidon, D. Fleisher. Absorption potential: estimating the fraction absorbed for orally administered compounds. J Pharm Sci, 74:588-589, 1985.
41. R. Loebenberg and G.L. Amidon, Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards. Eur J Pharm Biopharm, 50(1): 3-12, 2000.