Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: Prevention by rbSEC1

Journal of Cell Science

Volumn 112, Issue 12, 1999, Pages 1865-1877

  Rowe, Joanna ^a   Corradi, Nicoletta ^a   Malosio, Maria Luisa ^b,c   Taverna, Elena ^a   Halban, Philippe ^d   Meldolesi, Jacopo ^a,b,c   Rosa, Patrizia ^a  

^a CNR   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c San Raf faele Institute   (Italy)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Golgi complex; Membrane transport; rbSec1 munc18 1; SNARE

Indexed keywords

CALRETICULIN; CHROMOGRANIN B; MANNOSIDASE; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CELL SURFACE; ENDOPLASMIC RETICULUM; EXOCYTOSIS; FIBROBLAST; GENETIC TRANSFECTION; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; NEUROSECRETION; NEUROSECRETORY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT;

ANIMALS; ANTIGENS, SURFACE; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; EXOCYTOSIS; GOLGI APPARATUS; MUNC18 PROTEINS; NERVE TISSUE PROTEINS; NEUROSECRETORY SYSTEMS; PC12 CELLS; RATS; SYNTAXIN 1; TRANSFECTION; VESICULAR TRANSPORT PROTEINS;

ANIMALIA;

EID: 0032775945     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Aalto, M. K., Keranen, S. and Ronne, H. (1992). A family of proteins involved in intracellular transport Cell 68, 181-182.
2. Aalto, M. K., Ronne, H. and Keranen, S. (1993). Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport. EMBO J. 12, 4095-4104.
3. Advani, R. J., Bae, H. R., Bock, J. B., Chao, D. S., Doung, Y. C., Prekeris, R., Yoo, J. S. and Scheller, R. H. (1998). Seven novel mammalian snare proteins localize to distinct membrane compartments. J. Biol. Chem. 273, 10317-10324.
4. Armstrong, J., Thompson, N., Squire, J. H., Smith, J., Hayes, B. and Solari, R. (1996). Identification of a novel member of the Rab8 family from the rat basophilic Leukaemia cell line, RBL. 2H3. J. Cell Sci. 109, 1265-1274.
5. Annaert, W. G., Beker, B., Kistner, U., Reth, M. and Jahn, R. (1997). Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31. J. Cell Biol. 139, 1397-1410.
6. Bennett, M. K., Garcia-Arraras, J. E., Elferink, L. A., Peterson, K., Fleming, A. M., Hazuka, C. D. and Scheller, R. H. (1993). The syntaxin family of vesicular transport receptors. Cell 74, 863-873.
7. Bennett, M. K. (1995). SNAREs and the specificity of transport vesicle targeting. Curr. Opin. Cell Biol. 7, 581-586.
8. Bittner, M. A., Bennett, M. K. and Holz, R. W. (1996). Evidence that syntaxin 1A is involved in storage in the secretory pathway. J Biol. Chem. 271, 11214-11221.
9. Bock, J. B., Lin, R. C. and Scheller, R. H. (1996). A new syntaxin family member implicated in targeting of intracellular transport vesicles. J. Biol. Chem. 271, 17961-17965.
10. Bock, J. B., Klumperman, J., Davanger, S. and Scheller, R. H. (1997). Syntaxin 6 functions in trans-Golgi network vesicle trafficking. Mol. Biol. Cell. 8, 1261-1271.
11. Burgoyne, R. D. and Morgan, A. (1998). Analysis of regulated exocytosis in adrenal chromaffin cells -insights into NSF/SNAP/SNARE function BioEssays 20, 328-335.
12. Calakos, N., Bennett, M. K., Peterson, K. E. and Scheller, R. H. (1994). Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. Science 263, 1146-1149.
13. Clementi, E., Racchetti, G., Zacchetti, D., Panzeri, M. C. and Meldolesi, J. (1992). Differential expression of markers and activities in a goup of PC12 nerve cell clones. Eur. J. Neurosci. 4, 944-953.
14. Corradi, N., Borgonovo, B., Clementi, E., Bassetti, M., Racchetti, G., Consalez, G. G., Huttner, W. B., Meldolesi, J. and Rosa, P. (1996). Overall lack of regulated secretion in a PC12 variant cell clone. J. Biol. Chem. 271, 27116-27124.
15. Dascher, C., Matteson, J. and Balch, W. E. (1994). Syntaxin 5 regulates endoplasmic reticulum to Golgi transport. J. Biol. Chem. 269, 29363-29366.
16. De Camilli, P. and Takei, K. (1996). Molecular mechanisms in synaptic vesicle endocytosis and recycling. Neuron 16, 481-486.
17. Delgrossi, M. H., Breuza, L., Mirre, C., Chavrier, P. and Le Bivic, A. (1997). Human syntaxin 3 is localized apically in human intestinal cells. J. Cell Sci. 110, 2207-2214.
18. Dresbach, T., Burns, M. E., O'Connor, V., DeBello, W. M., Betz, H. and Augustine, G. J. (1998). A neuronal Sec1 homolog regulates neurotransmitler release at the squid giant synapse. J. Neurosci. 18, 923-932.
19. Galli, T., Zahraoui, A., Vaidyanathan, V. V., Raposo, G., Tian, J. M., Karin, M., Niemann, H., Louvard, D. (1998). A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane ofepithelial cells. Mol. Biol. Cell 9, 1437-1448
20. Garcia, E. P., Gatti, E., Butler, M., Burton, J. and De Camilli, P. (1994). A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxin. Proc. Nat. Acad. Sci. USA 91, 2003-2007.
21. Garcia, E. P., McPherson, P. S., Chilcote, T. J., Takei, K. and De Camilli, P. (1995). rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin. J. Cell Biol. 129, 105-120.
22. Gengyo-Ando, K., Kamiya, Y., Yamakawa, A., Kodaira, K., Nishiwaki, K., Miwa, J., Hori, I. and Hosono, R. (1993). The C. elegans unc-18 gene encodes a protein expressed in motor neurons. Neuron 11, 703-711.
23. Gengyo-Ando, K., Kitayama, H. Mukaida, M. and Ikawa, Y. (1996). A murine neuronal specific homolog corrects cholinergic defects in caernorhabditis elegans unc-18 mutants. J. Neurosci. 16, 6695-6702.
24. Gonzalo, S. and Linder, M. E. (1998). SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway. Mol. Biol. Cell 9, 585-597.
25. Halachmi, N. and Lev, Z. (1996). The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion. J. Neurochem. 66, 889-897.
26. Harrison, S. D., Broadie, K., van de Goor, J. and Rubin, G. M. (1994). Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission. Neuron 13, 555-566.
27. Hata, Y., Slaughter, C. A. and Südhof, T. C. (1993). Synaptic vesicle fusion complex contains unc-18 homologue bound to synatxin. Nature 366, 347-351.
28. Hata, Y. and Südhof, T. C. (1995). A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. J. Biol. Chem. 270, 13022-13028.
29. Hay, J. C. and Scheller, R. H. (1997). SNAREs and NSF in targeted membrane fusion. Curr. Opin. Cell Biol. 9, 505-512.
30. Hay, J. C., Klumperman, J., Oorschot, V., Steegmaier, M., Kuo, C. S. and Scheller, R. H. (1998). Localization, dynamics and protein interactions reveal distinct roles for ER and Golgi SNAREs. J. Cell Biol. 141, 1489-1502.
31. Hodel, A., Schafer, T., Gerosa, D. and Burger, M. M. (1994). In chromaffin cells, the mammalian Seclp homologue is a syntaxin 1A-binding protein associated with chromaffin granules. J. Biol. Chem. 269, 8623-8626.
32. Jahn, R. and Hanson, P. I. (1998). Membrane fusion. SNAREs line up in new environment. Nature 393, 14-15.
33. Jäntti, J., Keränen, S., Toikkanen, J., Kuismanen, E., Ehnholm, C., Söderlund, H. and Olkkonen, V. M. (1994). Membrane insertion and intracellular transport of yeast syntaxin Sso2p in mammalian cells. J. Cell Sci. 107, 3623-3633.
34. Lin, R. C. and Scheller, R. H. (1997). Structural organization of the synaptic exocytosis core complex. Neuron 19, 1087-1094.
35. Lippincott-Schwartz, J., Cole, N. and Presley, J. (1998). Unravelling Golgi membrane traffic with green fluorescent protein chimeras. Trends Cell Biol. 8, 16-20.
36. Low, S. H., Chapin, S. J., Weimbs, T., Komuves, L. G., Bennett, M. K. and Mostov, K. E. (1996). Differential localization of syntaxin isoforms in polarized madin-darby canine kidney cells. Mol. Biol. Cell 7, 2007-2018.
37. Low, S. H., Roche, P. A., Anderson, H. A., van Ijzendoorn, S. C., Zhang, M., Mostov, K. E. and Weimbs, T. (1998). Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells. J. Biol. Chem. 273, 3422-3430.
38. Ludger, J. and Galli, T. (1998). Exocytosis: SNAREs drum up! Eur. J. Neurosci. 10, 415-422.
39. Luzio, J. P., Brake, B., Banting, G., Howell, K. E., Braghetta, P. and Stanley, K. K. (1990). Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38). Biochem. J. 270, 97-105.
40. Monier, S., Chardin, P., Robineau, S. and Goud, B. (1998). Overexpression of the ARF1 exchange factor ARNO inhibits the early secretory pathway and causes disassembly of the Golgi complex. J. Cell Sci. 111, 3427-3436.
41. Patel, S. K., Indig, F. E., Olivieri, N., Levine, N. D. and Latterich, M. (1998). Organelle membrane fusion: a novel function for the syntaxin homolog Ufelp in ER membrane fusion. Cell 92, 611-620.
42. Pietrini, G., Sun, Y. J., Edelmann, L., Rudnick, G. and Caplan, M. J. (1994). The axonal γ-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells. J. Biol. Chem. 269, 4668-4674.
43. Pevsner, J., Hsu, S. C. and Scheller, R. H. (1994a). nSec-1: a neural-specific syntaxin-binding protein. Proc. Nat. Acad. Sci USA 91, 1445-1449.
44. Pevsner, J., Hsu, S. C., Braun, J. E., Calakos, N., Ting, A. E., Bennett, M. K. and Scheller, R. H. (1994b). Specificity and regulation of a synaptic vesicle docking complex. Neuron 13, 353-361.
45. Pezzati, R., Bossi, M., Podini, P., Meldolesi, J. and Grohovaz, F. (1997) High resolution calcium mapping of the ER-Golgi-exocytic membrane system. Electron energy loss imaging analysis of quick frozen-freeze dryed PC12 cells. Mol. Biol. Cell 8, 1501-1512.
46. Rabouille, C., Kondo, H., Newman, R., Hui, N., Freemont, P. and Warren, G. (1998). Syntaxin 5 is a common component of the NSF-and p97 mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro. Cell 92, 603-610.
47. Rayner, J. C. and Pelham, H. R. B. (1997). Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast. EMBO J. 16, 1832-1841.
48. Robinson, L. J. and Martin, F. J. (1998). Docking and fusion in neurosecretion. Curr. Opin. Cell Biol. 10, 483-492.
49. Rosa, P., Hille, A., Lee, R. W., Zanini, A., De Camilli, P. and Huttner, W. B. (1985). Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway. J. Cell Biol. 101, 1999-2011.
50. Rosa, P., Weiss, U., Pepperkok, R., Ansorge, W., Niehrs, C., Stelzer, E. H. and Huttner, W. B. (1989). An antibody against secretogranin I (chromogranin B) is packaged into secretory granules. J. Cell Biol. 109, 17-34.
51. Rosa, P., Bassetti, M., Weiss, U. and Huttner, W. B. (1992). Widespread occurence of chromogranins/secretogranins in the matrix of secretory granules of endocrinological silent pituitary adenomas J. Histochem. Cytochem. 40, 523-533.
52. Rosa, P. and Gerdes, H.-H. (1994). The granin protein family: markers for neuroendocrine cells and tools for the diagnosis of neuroendocrine tumours. J. Endocrinol. Invest. 17, 207-225.
53. Rothmann, J. E. (1994). Mechanisms of intracellular protein transport. Nature 372, 55-63.
54. Rothman, J. E. and Warren, G. (1994). Implications of the SNARE hypothesis for intracellular membrane topology and dynamics. Curr. Biol. 4, 220-233.
55. Rothman, J. E. and Söllner, T. H. (1997). Throttles and dampers: controlling the engine of membrane fusion Science. 276, 1212-1213,
56. Sadoul, K., Lang, J., Montecucco, C., Weller, U., Regazzi, R., Catsicas, S., Wollheim, C. B. and Halban, P. A. (1995). SNAP-25 is expressed in islets of langerhans and is involved in insulin release. J. Cell Biol. 128, 1019-1028.
57. Schiavo, G., Rossetto, O. and Montecucco, C. (1994). Clostridial neurotoxins as tools to investigate the molecular events of neurotransmitter release. Seminars Cell Biol. 5, 221-229.
58. Schulze, K. L., Littleton, J. T., Salzberg, A., Halachmi, N., Stern, M., Lev, Z. and Bellen, H. J. (1994). rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sec1/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo. Neuron 13, 1099-1108.
59. Söllner, T. Whiteheart, S. W., Brunner, M., Erdjument-Bromage, H., Geromanos, S., Tempst, P. and Rothman, J. E. (1993). SNAP receptors implicated in vesicle targeting and fusion. Nature 362, 318-324.
60. Südhof, T. C. (1995). The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375, 645-653.
61. Tellam, J. T., McIntosh, S. and James, D. E. (1995). Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. J. Biol. Chem. 270, 5857-5863.
62. Velasco A., Hendricks, L. C., Moremen, K., Tulsiano, D. R., Touster, O. and Farquhar, M. G. (1993). Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I and II. J. Cell Biol. 122, 39-51.
63. Walch-Solimena, C., Blasi, J., Edelmann, L., Chapman, E. R., VonMollard, G. F. and Jahn, R. (1995). The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicles recycling. J. Cell Biol. 128, 637-645.
64. Weimbs, T., Mostov, K., Low, S. H. and Hofmann, R. (1998). A model for structural similarity between different SNARE complexes based on sequence relationships. Trends Cell Biol. 8, 260-262.