Synthesis, characterization and deepening in the comprehension of the biological action mechanisms of a new nickel complex with antiproliferative activity

Journal of Inorganic Biochemistry

Volumn 103, Issue 5, 2009, Pages 666-677

  Buschini, Annamaria ^a   Pinelli, Silvana ^a   Pellacani, Claudia ^a   Giordani, Federica ^a   Ferrari, Marisa Belicchi ^a   Bisceglie, Franco ^a   Giannetto, Marco ^a   Pelosi, Giorgio ^a   Tarasconi, Pieralberto ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Apoptosis; DNA damage; Nickel complexes; Telomerase activity; Thiosemicarbazones

Indexed keywords

(BIS CITRONELLALTHIOSEMICARBAZONATO)NICKEL; ALDEHYDE; CASPASE 3; NICKEL COMPLEX; PROTEIN BCL 2; PROTEIN P53; TELOMERASE; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL NUCLEUS; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG SYNTHESIS; ENZYME ACTIVITY; HISTIOCYTIC LYMPHOMA; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PROTEIN FUNCTION;

APOPTOSIS; CASPASES; CELL CYCLE; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; CRYSTALLOGRAPHY, X-RAY; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MODELS, MOLECULAR; NICKEL; ORGANIC CHEMICALS; PROTO-ONCOGENE PROTEINS C-BCL-2; TELOMERASE; THIOSEMICARBAZONES; U937 CELLS;

EID: 64649095121     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2008.12.016     Document Type: Article

References (59)

1. Wang D., and Lippard S.J. Nat. Rev. 4 (2005) 307-320
2. Brabec V., and Nov́akov́a O. Drug Res. Update. 9 (2006) 111-122
3. G.J. Hutchings, M. Brust, H. Schmidbaur (Eds.), Thematic issue: gold: chemistry, materials and catalysis, Chem. Soc. Rev., vol. 37, 2008, pp. 1745-2140.
4. Agrawal K.C., and Sartorelli A.C. J. Med. Chem. 12 (1969) 771-774
5. Antholine W., Knight J., Whelan H., and Petering D.H. Mol. Pharmacol. 13 (1977) 89-98
6. Klayman D.L., Bartosovich J.F., Griffin T.S., Mason C.J., and Scovill J.P. J. Med. Chem. 22 (1979) 855-862
7. Klayman D.L., Scovill J.P., Bartosovich J.F., Mason C., and Mason J. J. Med. Chem. 22 (1979) 1367-1373
8. Padhyé S., and Kauffman G.B. Coord. Chem. Rev. 63 (1985) 127-160
9. Byrnes R.W., Mohan M., Antholine W.E., Xu R.X., and Petering D.H. Biochemistry 29 (1990) 7046-7053
10. Iakovidou Z., Papageorgiou A., Demertzis M.A., Mioglou E., Mourelatos D., Kotsis A., Nath Yadav P., and Kovala-Demertzi D. Anticancer Drugs 12 (2001) 65-70
11. Kolocouris A., Dimas K., Pannecouque C., Witvrouw M., Foscolos G.B., Stamatiou G., Fytas G., Zoidis G., Kolocouris N., Andrei G., Snoeck R., and De Clercq E. Bioorg. Med. Chem. 12 (2002) 723-727
12. Beraldo H., and Gambino D. Mini-Rev. Med. Chem. 4 (2004) 31-39
13. Knox J.J., Hotte S.J., Kollmannsberger C., Winquist E., Fisher B., and Eisenhauer E.A. Invest. New Drug. 25 (2007) 471-477
14. Mackenzie M.J., Saltman D., Hirte H., Low J., Johnson C., Pond G., and Moore M.J. Invest. New Drug. 25 (2007) 553-558
15. Baldini M., Belicchi-Ferrari M., Bisceglie F., Pelosi G., Pinelli S., and Tarasconi P. Inorg. Chem. 42 (2003) 2049-2055
16. Belicchi-Ferrari M., Bisceglie F., Casoli C., Durot S., Morgenstern-Badarau I., Pelosi G., Pilotti E., Pinelli S., and Tarasconi P. J. Med. Chem. 48 (2005) 1671-1675
17. Belicchi-Ferrari M., Bisceglie F., Pelosi G., Tarasconi P., Albertini R., Dall'Aglio P.P., Pinelli S., Bergamo A., and Sava G. J. Inorg. Biochem. 98 (2004) 301-312
18. Tarasconi P., Capacchi S., Pelosi G., Cornia M., Albertini R., Bonati A., Dall'Aglio P.P., Lunghi P., and Pinelli S. Bioorg. Med. Chem. 8 (2000) 157-162
19. Belicchi-Ferrari M., Bisceglie F., Pelosi G., Sassi M., Tarasconi P., Cornia M., Capacchi S., Albertini R., and Pinelli S. J. Inorg. Biochem. 90 (2002) 113-126
20. Bisceglie F., Baldini M., Belicchi-Ferrari M., Buluggiu E., Careri M., Pelosi G., Pinelli S., and Tarasconi P. Eur. J. Med. Chem. 42 (2007) 627-634
21. Sheldrick G. SADABS: Siemens Area Detector Absorption Correction Software (1996), University of Goettingen, Germany
22. Altomare A., Burla M.C., Camalli M., Cascarano G., Giacovazzo C., Guagliardi A., Moliterni A.G., Polidori G., and Spagna R. J. Appl. Crystallogr. 32 (1999) 115-119
23. Sheldrick G. SHELXL97: Program for Structure Refinement (1997), University of Goettingen, Germany
24. Farrugia L.J. WinGX 1.64. J. Appl. Crystallogr. A 32 (1999) 837-838
25. International Tables for X-ray Crystallography, vol. C, Kluwer, Dordrecht, Netherlands; 1992.
26. Nardelli M. PARST95. J. Appl. Crystallogr. 28 (1995) 659
27. Wells D., and Young C. Ray-Tracing Creations (1993), Waite Group Press, Corte Madera, CA
28. Merk O., and Speit G. Environ. Mol. Mutagen. 33 (1999) 167-172
29. Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L., Coviello G.M., Wright W.E., Weinrich S.L., and Shay J.W. Science 266 (1994) 2011-2015
30. Langford L.A., Piatyszek M.A., Shay J.W., and Schold S.C. Lancet 346 (1995) 1267-1268
31. Wright W.E., Shay J.W., and Piatyszek M.A. Nucl. Acids Res. 23 (1995) 3794-3795
32. Kim N.W., and Wu F. Nucl. Acids Res. 25 (1997) 2595-2597
33. Yui J., Chiu C.P., and Lansdorp P.M. Blood 91 (1998) 3255-3262
34. Engelhardt M., Mackenzie K., Drullinsky P., Silver R.T., and Moore M.A.S. Cancer Res. 60 (2000) 610-617
35. Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. Exp. Cell Res. 175 (1988) 184-191
36. Collins A.R., Ma A.G., and Duthie S.J. Mutat. Res. 336 (1995) 69-77
37. Martin A. Physical Pharmacy - Physical Chemical Principles in the Pharmaceutical Sciences (1993), Lea and Febiger, Philadelphia
38. Martinez M., Augsburger L., Johnston T., and Warren Jones W. Adv. Drug Deliv. Rev. 54 (2002) 805-824
39. Green D.R., and Kroemer G. Science 305 (2004) 626-629
40. Danial N.N., and Korsmeyer S.J. Cell 116 (2004) 205-219
41. Kakkar P., and Singh B.K. Mol. Cell. Biochem. 305 (2007) 235-253
42. Collins A.R., Dobson V.L., Dusinska M., Kennedy G., and Stetina R. Mutat. Res. 375 (1997) 183-193
43. Collins A.R. Methods Mol. Biol. 203 (2002) 163-177
44. Lee S.H., Choi J.G., and Cho M.H. J. Korean Med. Sci. 16 (2001) 165-168
45. Kastan M.B., Onyekwere O., Sidransky D., Vogelstein B., and Craig R.W. Cancer Res. 51 (1991) 6304-6311
46. Pang S.K., Yu C.W., Guan H., Au-Yeung S.C., and Ho Y.P. Biochem. Biophys. Res. Commun. 20 (2007) 235-240
47. Richardson D.R. Crit. Rev. Oncol. Hematol. 42 (2002) 267-281
48. Taylor W.R., and Stark G.R. Oncogene 20 (2001) 1803-1815
49. O'Brien V., and Brown R. Carcinogenesis 27 (2006) 682-692
50. Reynolds M., Stoddard L., Bespalov I., and Zhitkovich A. Nucl. Acids Res. 35 (2007) 465-476
51. Weathe N.J., Brodie C.R., Collins J.G., Kemp S., and Aldrich-Wright J.R. Mini-Rev. Med. Chem. 7 (2007) 627-648
52. Shao J., Zhou B., Di Bilio A.J., Zhu L., Wang T., Qi C., Shih J., and Yen Y. Mol. Cancer Ther. 3 (2006) 586-592
53. Chen J., and Stubbe J. Nat. Rev. Cancer 5 (2005) 102-112
54. M Pulido D., and Parrish A.R. Mutat. Res. 533 (2003) 227-241
55. Katakura Y. Biosci. Biotechnol. Biochem. 70 (2006) 1076-1081
56. Pizzimenti S., Briatore F., Laurora S., Toaldo C., Maggio M., DeGrandi M., Meaglia L., Menegatti E., Giglioni B., Dianzani M.U., and Barrera G. Free Rad. Biol. Med. 40 (2006) 1578-1591
57. Passos J.F., Saretzki G., and von Zglinicki T. Nucl. Acid Res. 35 (2007) 7505-7513
58. Shay J.W., and Wright W.E. Carcinogenesis 5 (2005) 867-874
59. Park C., Jung J.H., Kim N.D., and Choi Y.H. Int. J. Oncol. 30 (2007) 291-298