-
1
-
-
0027248652
-
Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high
-
Badger TM, Huang J, Ronis M, and Lumpkin CK (1993) Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high. Biochem Biophys Res Commun 190:780-785.
-
(1993)
Biochem Biophys Res Commun
, vol.190
, pp. 780-785
-
-
Badger, T.M.1
Huang, J.2
Ronis, M.3
Lumpkin, C.K.4
-
2
-
-
0242382793
-
Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism
-
Benowitz NL, Peng M, and Jacob P 3rd (2003) Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. Clin Pharmacol Ther 74:468-474.
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 468-474
-
-
Benowitz, N.L.1
Peng, M.2
Jacob III, P.3
-
3
-
-
0035894132
-
CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
-
Cederbaum AI, Wu D, Mari M, and Bai J (2001) CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radic Biol Med 31:1539-1543.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1539-1543
-
-
Cederbaum, A.I.1
Wu, D.2
Mari, M.3
Bai, J.4
-
4
-
-
0028222128
-
Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration
-
Forkert PG, Redza ZM, Mangos S, Park SS, and Tam SP (1994) Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration. Drug Metab Dispos 22:248-253.
-
(1994)
Drug Metab Dispos
, vol.22
, pp. 248-253
-
-
Forkert, P.G.1
Redza, Z.M.2
Mangos, S.3
Park, S.S.4
Tam, S.P.5
-
5
-
-
25444520229
-
Pharmacotherapy for nicotine dependence
-
Henningfield JE, Fant RV, Buchhalter AR, and Stitzer ML (2005) Pharmacotherapy for nicotine dependence. CA Cancer J Clin 55:281-299; quiz 322-283,325.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 281-299
-
-
Henningfield, J.E.1
Fant, R.V.2
Buchhalter, A.R.3
Stitzer, M.L.4
-
6
-
-
0034756293
-
Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
-
Howard LA, Micu AL, Sellers EM, and Tyndale RF (2001) Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver. J Pharmacol Exp Ther 299:542-550.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 542-550
-
-
Howard, L.A.1
Micu, A.L.2
Sellers, E.M.3
Tyndale, R.F.4
-
7
-
-
0037739660
-
Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
-
Howard LA, Miksys S, Hoffmann E, Mash D, and Tyndale RF (2003) Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics. Br J Pharmacol 138:1376-1386.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1376-1386
-
-
Howard, L.A.1
Miksys, S.2
Hoffmann, E.3
Mash, D.4
Tyndale, R.F.5
-
8
-
-
33645100613
-
Chronic nicotine increases CYP2E1, an enzyme associated with alcohol and nicotine dependence, in monkey brain
-
Prague, Czech Republic
-
Joshi M, Miksys S, and Tyndale RF (2005) Chronic nicotine increases CYP2E1, an enzyme associated with alcohol and nicotine dependence, in monkey brain, in Proceedings of the Society for Research in Nicotine and Tobacco, pp 80, Prague, Czech Republic.
-
(2005)
Proceedings of the Society for Research in Nicotine and Tobacco
, pp. 80
-
-
Joshi, M.1
Miksys, S.2
Tyndale, R.F.3
-
9
-
-
33645106930
-
Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
-
Joshi M and Tyndale RF (2005) Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine. Neuropharmacology 20.
-
(2005)
Neuropharmacology
, pp. 20
-
-
Joshi, M.1
Tyndale, R.F.2
-
11
-
-
0034727894
-
Acute nicotine decreases and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus
-
Kenny PJ, File SE, and Rattray M (2000) Acute nicotine decreases and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain Res Mol Brain Res 85:234-238.
-
(2000)
Brain Res Mol Brain Res
, vol.85
, pp. 234-238
-
-
Kenny, P.J.1
File, S.E.2
Rattray, M.3
-
12
-
-
0141494281
-
CYP2E1: Biochemistry, toxicology, regulation and function in ethanol-induced liver injury
-
Kessova I and Cederbaum AI (2003) CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury. Curr Mol Med 3:509-518.
-
(2003)
Curr Mol Med
, vol.3
, pp. 509-518
-
-
Kessova, I.1
Cederbaum, A.I.2
-
13
-
-
0025020532
-
Induction of rat hepatic P450IIE1 (CYP 2E1) by pyridine: Evidence for a role of protein synthesis in the absence of transcriptional activation
-
Kim SG and Novak RF (1990) Induction of rat hepatic P450IIE1 (CYP 2E1) by pyridine: evidence for a role of protein synthesis in the absence of transcriptional activation. Biochem Biophys Res Commun 166:1072-1079.
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 1072-1079
-
-
Kim, S.G.1
Novak, R.F.2
-
14
-
-
0035800645
-
Region-specific transcriptional response to chronic nicotine in rat brain
-
Konu O, Kane JK, Barrett T, Vawter MP, Chang R, Ma JZ, Donovan DM, Sharp B, Becker KG, and Li MD (2001) Region-specific transcriptional response to chronic nicotine in rat brain. Brain Res 909:194-203.
-
(2001)
Brain Res
, vol.909
, pp. 194-203
-
-
Konu, O.1
Kane, J.K.2
Barrett, T.3
Vawter, M.P.4
Chang, R.5
Ma, J.Z.6
Donovan, D.M.7
Sharp, B.8
Becker, K.G.9
Li, M.D.10
-
15
-
-
0023873548
-
Molecular regulation of ethanol-inducible cytochrome P450-IIEI in hamsters
-
Kubota S, Lasker JM, and Lieber CS (1988) Molecular regulation of ethanol-inducible cytochrome P450-IIEI in hamsters. Biochem Biophys Res Commun 150:304-310.
-
(1988)
Biochem Biophys Res Commun
, vol.150
, pp. 304-310
-
-
Kubota, S.1
Lasker, J.M.2
Lieber, C.S.3
-
16
-
-
0032873460
-
Circadian expression of the steroid 15 α-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP
-
Lavery DJ, Lopez-Molina L, Margueron R, Fleury-Olela F, Conquet F, Schibler U, and Bonfils C (1999) Circadian expression of the steroid 15 α-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP. Mol Cell Biol 19:6488-6499.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6488-6499
-
-
Lavery, D.J.1
Lopez-Molina, L.2
Margueron, R.3
Fleury-Olela, F.4
Conquet, F.5
Schibler, U.6
Bonfils, C.7
-
17
-
-
0031901150
-
Site-selective differences in cytochrome P450 isoform activities. Comparison of expression in rat and rhesus monkey lung and induction in rats
-
Lee C, Watt KC, Chang AM, Plopper CG, Buckpitt AR, and Pinkerton KE (1998) Site-selective differences in cytochrome P450 isoform activities. Comparison of expression in rat and rhesus monkey lung and induction in rats. Drug Metab Dispos 26:396-400.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 396-400
-
-
Lee, C.1
Watt, K.C.2
Chang, A.M.3
Plopper, C.G.4
Buckpitt, A.R.5
Pinkerton, K.E.6
-
18
-
-
9744285770
-
Time-dependent changes in transcriptional profiles within five rat brain regions in response to nicotine treatment
-
Li MD, Kane JK, Wang J, and Ma JZ (2004) Time-dependent changes in transcriptional profiles within five rat brain regions in response to nicotine treatment. Brain Res Mol Brain Res 132:168-180.
-
(2004)
Brain Res Mol Brain Res
, vol.132
, pp. 168-180
-
-
Li, M.D.1
Kane, J.K.2
Wang, J.3
Ma, J.Z.4
-
19
-
-
0030935567
-
Cytochrome P-4502E1: Its physiological and pathological role
-
Lieber CS (1997) Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 77:517-544.
-
(1997)
Physiol Rev
, vol.77
, pp. 517-544
-
-
Lieber, C.S.1
-
20
-
-
0033053587
-
Microsomal ethanol-oxidizing system (MEOS): The first 30 years (1968-1998) - A review
-
Lieber CS (1999) Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998) - a review. Alcohol Clin Exp Res 23:991-1007.
-
(1999)
Alcohol Clin Exp Res
, vol.23
, pp. 991-1007
-
-
Lieber, C.S.1
-
21
-
-
0028898120
-
Role of the liver-enriched transcription factor HNF-1 alpha in expression of the CYP2E1 gene
-
Liu SY and Gonzalez FJ (1995) Role of the liver-enriched transcription factor HNF-1 alpha in expression of the CYP2E1 gene. DNA Cell Biol 14:285-293.
-
(1995)
DNA Cell Biol
, vol.14
, pp. 285-293
-
-
Liu, S.Y.1
Gonzalez, F.J.2
-
22
-
-
0027365068
-
Acetone-dependent regulation of cytochromes P4502E1 and P4502B1 in rat nasal mucosa
-
Longo V and Ingelman-Sundberg M (1993) Acetone-dependent regulation of cytochromes P4502E1 and P4502B1 in rat nasal mucosa. Biochem Pharmacol 46:1945-1951.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 1945-1951
-
-
Longo, V.1
Ingelman-Sundberg, M.2
-
23
-
-
0041430939
-
Rat hepatic CYP2E1 is induced by very low nicotine doses: An investigation of induction, time course, dose response and mechanism
-
Micu AL, Miksys S, Sellers EM, Koop DR, and Tyndale RF (2003) Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response and mechanism. J Pharmacol Exp Ther 306:941-947.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 941-947
-
-
Micu, A.L.1
Miksys, S.2
Sellers, E.M.3
Koop, D.R.4
Tyndale, R.F.5
-
24
-
-
0034017040
-
Regional and cellular induction of nicotinemetabolizing CYP2B1 in rat brain by chronic nicotine treatment
-
Miksys S, Hoffmann E, and Tyndale RF (2000) Regional and cellular induction of nicotinemetabolizing CYP2B1 in rat brain by chronic nicotine treatment. Biochem Pharmacol 59:1501-1511.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 1501-1511
-
-
Miksys, S.1
Hoffmann, E.2
Tyndale, R.F.3
-
25
-
-
3042519581
-
The unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics
-
Miksys S and Tyndale RF (2004) The unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics. Drug Metab Rev 36:313-333.
-
(2004)
Drug Metab Rev
, vol.36
, pp. 313-333
-
-
Miksys, S.1
Tyndale, R.F.2
-
27
-
-
0035877348
-
Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: A new metabolic pathway?
-
Nissbrandt H, Bergquist F, Jonason J, and Engberg G (2001) Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: a new metabolic pathway? Synapse 40:294-301.
-
(2001)
Synapse
, vol.40
, pp. 294-301
-
-
Nissbrandt, H.1
Bergquist, F.2
Jonason, J.3
Engberg, G.4
-
28
-
-
0034251950
-
The alcohol-inducible form of cytochrome P450 (CYP 2E1): Role in toxicology and regulation of expression
-
Novak RF and Woodcroft KJ (2000) The alcohol-inducible form of cytochrome P450 (CYP 2E1): role in toxicology and regulation of expression. Arch Pharm Res (NY) 23:267-282.
-
(2000)
Arch Pharm Res (NY)
, vol.23
, pp. 267-282
-
-
Novak, R.F.1
Woodcroft, K.J.2
-
29
-
-
0342980835
-
Novel metabolic pathway of estrone and 17beta-estradiol catalyzed by cytochrome P-450
-
Ohe T, Hirobe M, and Mashino T (2000) Novel metabolic pathway of estrone and 17beta-estradiol catalyzed by cytochrome P-450. Drug Metab Dispos 28:110-112.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 110-112
-
-
Ohe, T.1
Hirobe, M.2
Mashino, T.3
-
30
-
-
0034307196
-
Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
-
Peng HM and Coon MJ (2000) Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2. Arch Biochem Biophys 382:129-137.
-
(2000)
Arch Biochem Biophys
, vol.382
, pp. 129-137
-
-
Peng, H.M.1
Coon, M.J.2
-
31
-
-
0020068521
-
Increase in hepatic microsomal ethanol oxidation by a single dose of ethanol
-
Petersen DR, Atkinson N, and Hjelle JJ (1982) Increase in hepatic microsomal ethanol oxidation by a single dose of ethanol. J Pharmacol Exp Ther 221:275-281.
-
(1982)
J Pharmacol Exp Ther
, vol.221
, pp. 275-281
-
-
Petersen, D.R.1
Atkinson, N.2
Hjelle, J.J.3
-
32
-
-
0024361306
-
Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes
-
Porter TD, Khani SC, and Coon MJ (1989) Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes. Mol Pharmacol 36:61-65.
-
(1989)
Mol Pharmacol
, vol.36
, pp. 61-65
-
-
Porter, T.D.1
Khani, S.C.2
Coon, M.J.3
-
33
-
-
2342493476
-
Regulation of the cytochrome P450 2A genes
-
Su T and Ding X (2004) Regulation of the cytochrome P450 2A genes. Toxicol Appl Pharmacol 199:285-294.
-
(2004)
Toxicol Appl Pharmacol
, vol.199
, pp. 285-294
-
-
Su, T.1
Ding, X.2
-
34
-
-
5644226194
-
The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
-
Tambyrajah WS, Doran E, Wood JD, and McGivan JD (2004) The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone. Arch Biochem Biophys 431:252-260.
-
(2004)
Arch Biochem Biophys
, vol.431
, pp. 252-260
-
-
Tambyrajah, W.S.1
Doran, E.2
Wood, J.D.3
McGivan, J.D.4
-
35
-
-
0033958619
-
Cytochrome P4502E (CYP2E) in brain: Constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization
-
Upadhya SC, Tirumalai PS, Boyd MR, Mori T, and Ravindranath V (2000) Cytochrome P4502E (CYP2E) in brain: constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization. Arch Biochem Biophys 373:23-34.
-
(2000)
Arch Biochem Biophys
, vol.373
, pp. 23-34
-
-
Upadhya, S.C.1
Tirumalai, P.S.2
Boyd, M.R.3
Mori, T.4
Ravindranath, V.5
-
36
-
-
5444243967
-
Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced mouse model of Parkinson's disease
-
Vaglini F, Pardini C, Viaggi C, Bartoli C, Dinucci D, and Corsini GU (2004) Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced mouse model of Parkinson's disease. J Neurochem 91:285-298.
-
(2004)
J Neurochem
, vol.91
, pp. 285-298
-
-
Vaglini, F.1
Pardini, C.2
Viaggi, C.3
Bartoli, C.4
Dinucci, D.5
Corsini, G.U.6
-
37
-
-
0035544925
-
Cytochrome p450 and parkinsonism: Protective role of CYP2E1
-
Vaglini F, Pardini C, Viaggi C, and Corsini GU (2001) Cytochrome p450 and parkinsonism: protective role of CYP2E1. Funct Neurol 16:107-112.
-
(2001)
Funct Neurol
, vol.16
, pp. 107-112
-
-
Vaglini, F.1
Pardini, C.2
Viaggi, C.3
Corsini, G.U.4
-
38
-
-
0032101152
-
Co-localization of P450 enzymes in the rat substantia nigra with tyrosine hydroxylase
-
Watts PM, Riedl AG, Douek DC, Edwards RJ, Boobis AR, Jenner P, and Marsden CD (1998) Co-localization of P450 enzymes in the rat substantia nigra with tyrosine hydroxylase. Neuroscience 86:511-519.
-
(1998)
Neuroscience
, vol.86
, pp. 511-519
-
-
Watts, P.M.1
Riedl, A.G.2
Douek, D.C.3
Edwards, R.J.4
Boobis, A.R.5
Jenner, P.6
Marsden, C.D.7
-
39
-
-
0025811870
-
The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription
-
Xanthopoulos KG, Prezioso VR, Chen WS, Sladek FM, Cortese R, and Darnell JE Jr (1991) The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription. Proc Natl Acad Sci USA 88:3807-3811.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3807-3811
-
-
Xanthopoulos, K.G.1
Prezioso, V.R.2
Chen, W.S.3
Sladek, F.M.4
Cortese, R.5
Darnell Jr., J.E.6
-
40
-
-
0036299144
-
An in vivo pilot study characterizing the new CYP2A6*7, *8 and *10 alleles
-
Xu C, Rao YS, Xu B, Hoffmann E, Jones J, Sellers EM, and Tyndale RF (2002) An in vivo pilot study characterizing the new CYP2A6*7, *8 and *10 alleles. Biochem Biophys Res Commun 290:318-324.
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 318-324
-
-
Xu, C.1
Rao, Y.S.2
Xu, B.3
Hoffmann, E.4
Jones, J.5
Sellers, E.M.6
Tyndale, R.F.7
|