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Volumn 10, Issue , 2009, Pages

HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B2 PROTEIN; RAG1 PROTEIN; RAG2 PROTEIN; DNA; HOMEODOMAIN PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; OLIGONUCLEOTIDE; RAG 1 PROTEIN; RAG-1 PROTEIN;

EID: 64549115367     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-10-24     Document Type: Article
Times cited : (7)

References (31)
  • 1
    • 0036240127 scopus 로고    scopus 로고
    • The mechanism and regulation of chromosomal V(D)J recombination
    • 10.1016/S0092-8674(02)00675-X 11983152
    • Bassing CH Swat W Alt FW The mechanism and regulation of chromosomal V(D)J recombination Cell 2002, 109(Suppl):S45-55. 10.1016/ S0092-8674(02)00675-X 11983152
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Bassing, C.H.1    Swat, W.2    Alt, F.W.3
  • 2
    • 0034094425 scopus 로고    scopus 로고
    • The RAG proteins and V(D)J recombination: Complexes, ends, and transposition
    • 10.1146/annurev.immunol.18.1.495 10837067
    • Fugmann SD Lee AI Shockett PE Villey IJ Schatz DG The RAG proteins and V(D)J recombination: Complexes, ends, and transposition Annu Rev Immunol 2000, 18:495-527. 10.1146/annurev.immunol.18.1.495 10837067
    • (2000) Annu Rev Immunol , vol.18 , pp. 495-527
    • Fugmann, S.D.1    Lee, A.I.2    Shockett, P.E.3    Villey, I.J.4    Schatz, D.G.5
  • 3
    • 0035997348 scopus 로고    scopus 로고
    • V(D)J recombination: RAG proteins, repair factors, and regulation
    • 10.1146/annurev.biochem.71.090501.150203 12045092
    • Gellert M V(D)J recombination: RAG proteins, repair factors, and regulation Annu Rev Biochem 2002, 71:101-132. 10.1146/ annurev.biochem.71.090501.150203 12045092
    • (2002) Annu Rev Biochem , vol.71 , pp. 101-132
    • Gellert, M.1
  • 4
    • 0035800747 scopus 로고    scopus 로고
    • Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints
    • 10.1074/jbc.M103797200 11390401
    • Raghavan SC Kirsch IR Lieber MR Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints J Biol Chem 2001, 276(31):29126-29133. 10.1074/jbc.M103797200 11390401
    • (2001) J Biol Chem , vol.276 , Issue.31 , pp. 29126-29133
    • Raghavan, S.C.1    Kirsch, I.R.2    Lieber, M.R.3
  • 5
    • 0037033440 scopus 로고    scopus 로고
    • V(D)J-mediated translocations in lymphoid neoplasms: A functional assessment of genomic instability by cryptic sites
    • 10.1084/jem.20011578 11781368
    • Marculescu R Le T Simon P Jaeger U Nadel B V(D)J-mediated translocations in lymphoid neoplasms: A functional assessment of genomic instability by cryptic sites J Exp Med 2002, 195(1):85-98. 10.1084/jem.20011578 11781368
    • (2002) J Exp Med , vol.195 , Issue.1 , pp. 85-98
    • Marculescu, R.1    Le, T.2    Simon, P.3    Jaeger, U.4    Nadel, B.5
  • 6
    • 0037195805 scopus 로고    scopus 로고
    • Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia
    • 10.1074/jbc.M208353200 12228235
    • Kitagawa Y Inoue K Sasaki S Hayashi Y Matsuo Y Lieber MR Mizoguchi H Yokota J Kohno T Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia J Biol Chem 2002, 277(48):46289-46297. 10.1074/jbc.M208353200 12228235
    • (2002) J Biol Chem , vol.277 , Issue.48 , pp. 46289-46297
    • Kitagawa, Y.1    Inoue, K.2    Sasaki, S.3    Hayashi, Y.4    Matsuo, Y.5    Lieber, M.R.6    Mizoguchi, H.7    Yokota, J.8    Kohno, T.9
  • 7
    • 21744455557 scopus 로고    scopus 로고
    • Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro
    • 1168826 15988007 10.1128/MCB.25.14.5904-5919.2005
    • Raghavan SC Swanson PC Ma Y Lieber MR Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro Mol Cell Biol 2005, 25(14):5904-5919. 1168826 15988007 10.1128/MCB.25.14.5904-5919.2005
    • (2005) Mol Cell Biol , vol.25 , Issue.14 , pp. 5904-5919
    • Raghavan, S.C.1    Swanson, P.C.2    Ma, Y.3    Lieber, M.R.4
  • 8
    • 1542287213 scopus 로고    scopus 로고
    • A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex
    • 10.1038/nature02355 14999286
    • Raghavan SC Swanson PC Wu X Hsieh CL Lieber MR A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex Nature 2004, 428(6978):88-93. 10.1038/nature02355 14999286
    • (2004) Nature , vol.428 , Issue.6978 , pp. 88-93
    • Raghavan, S.C.1    Swanson, P.C.2    Wu, X.3    Hsieh, C.L.4    Lieber, M.R.5
  • 9
    • 33747892852 scopus 로고    scopus 로고
    • Recombinase, chromosomal translocations and lymphoid neoplasia: Targeting mistakes and repair failures
    • 10.1016/j.dnarep.2006.05.015 16798110
    • Marculescu R Vanura K Montpellier B Roulland S Le T Navarro JM Jager U McBlane F Nadel B Recombinase, chromosomal translocations and lymphoid neoplasia: Targeting mistakes and repair failures DNA Repair (Amst) 2006, 5(9-10):1246-1258. 10.1016/j.dnarep.2006.05.015 16798110
    • (2006) DNA Repair (Amst) , vol.5 , Issue.9-10 , pp. 1246-1258
    • Marculescu, R.1    Vanura, K.2    Montpellier, B.3    Roulland, S.4    Le, T.5    Navarro, J.M.6    Jager, U.7    McBlane, F.8    Nadel, B.9
  • 10
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • 10.1101/gad.3.7.1053 2777075
    • Hesse JE Lieber MR Mizuuchi K Gellert M V(D)J recombination: A functional definition of the joining signals Genes & Development 1989, 3(7):1053-1061. 10.1101/gad.3.7.1053 2777075
    • (1989) Genes & Development , vol.3 , Issue.7 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 11
    • 0029891597 scopus 로고    scopus 로고
    • Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage
    • 450263 8670820
    • Ramsden DA McBlane JF van Gent DC Gellert M Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage EMBO J 1996, 15(12):3197-3206. 450263 8670820
    • (1996) EMBO J , vol.15 , Issue.12 , pp. 3197-3206
    • Ramsden, D.A.1    McBlane, J.F.2    van Gent, D.C.3    Gellert, M.4
  • 12
    • 0029814965 scopus 로고    scopus 로고
    • DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences
    • 231568 8816481
    • Cuomo CA Mundy CL Oettinger MA DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences Mol Cell Biol 1996, 16(10):5683-5690. 231568 8816481
    • (1996) Mol Cell Biol , vol.16 , Issue.10 , pp. 5683-5690
    • Cuomo, C.A.1    Mundy, C.L.2    Oettinger, M.A.3
  • 13
    • 0030707531 scopus 로고    scopus 로고
    • RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution
    • 232550 9372925
    • Li W Swanson P Desiderio S RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution Mol Cell Biol 1997, 17(12):6932-6939. 232550 9372925
    • (1997) Mol Cell Biol , vol.17 , Issue.12 , pp. 6932-6939
    • Li, W.1    Swanson, P.2    Desiderio, S.3
  • 14
    • 34247604497 scopus 로고    scopus 로고
    • The structure-specific nicking of small heteroduplexes by the RAG complex: Implications for lymphoid chromosomal translocations
    • 10.1016/j.dnarep.2006.12.016 17307402
    • Raghavan SC Gu J Swanson PC Lieber MR The structure-specific nicking of small heteroduplexes by the RAG complex: Implications for lymphoid chromosomal translocations DNA Repair (Amst) 2007, 6(6):751-759. 10.1016/ j.dnarep.2006.12.016 17307402
    • (2007) DNA Repair (Amst) , vol.6 , Issue.6 , pp. 751-759
    • Raghavan, S.C.1    Gu, J.2    Swanson, P.C.3    Lieber, M.R.4
  • 15
    • 0033387958 scopus 로고    scopus 로고
    • The RAG1/RAG2 complex constitutes a 3' flap endonuclease: Implications for junctional diversity in V(D)J and transpositional recombination
    • 10.1016/S1097-2765(00)80223-3 10635319
    • Santagata S Besmer E Villa A Bozzi F Allingham JS Sobacchi C Haniford DB Vezzoni P Nussenzweig MC Pan ZQ et al The RAG1/RAG2 complex constitutes a 3' flap endonuclease: Implications for junctional diversity in V(D)J and transpositional recombination Mol Cell 1999, 4(6):935-947. 10.1016/ S1097-2765(00)80223-3 10635319
    • (1999) Mol Cell , vol.4 , Issue.6 , pp. 935-947
    • Santagata, S.1    Besmer, E.2    Villa, A.3    Bozzi, F.4    Allingham, J.S.5    Sobacchi, C.6    Haniford, D.B.7    Vezzoni, P.8    Nussenzweig, M.C.9    Pan, Z.Q.10
  • 16
    • 0035281548 scopus 로고    scopus 로고
    • HMG1 and 2, and related 'architectural' DNA-binding proteins
    • 10.1016/S0968-0004(01)01801-1 11246022
    • Thomas JO Travers AA HMG1 and 2, and related 'architectural' DNA-binding proteins Trends Biochem Sci 2001, 26(3):167-174. 10.1016/ S0968-0004(01)01801-1 11246022
    • (2001) Trends Biochem Sci , vol.26 , Issue.3 , pp. 167-174
    • Thomas, J.O.1    Travers, A.A.2
  • 17
    • 0033607614 scopus 로고    scopus 로고
    • Structure-specific binding of the two tandem HMG boxes of HMG1 to four-way junction DNA is mediated by the A domain
    • 10.1006/jmbi.1999.3150 10610765
    • Webb M Thomas JO Structure-specific binding of the two tandem HMG boxes of HMG1 to four-way junction DNA is mediated by the A domain J Mol Biol 1999, 294(2):373-387. 10.1006/jmbi.1999.3150 10610765
    • (1999) J Mol Biol , vol.294 , Issue.2 , pp. 373-387
    • Webb, M.1    Thomas, J.O.2
  • 18
    • 0034730950 scopus 로고    scopus 로고
    • High mobility group 1 and 2 proteins bind preferentially to DNA that contains bulky adducts induced by benzo[a]pyrene diol epoxide and N-acetoxy-acetylaminofluorene
    • 10.1016/S0304-3835(00)00517-6 10940504
    • Lanuszewska J Widlak P High mobility group 1 and 2 proteins bind preferentially to DNA that contains bulky adducts induced by benzo[a]pyrene diol epoxide and N-acetoxy-acetylaminofluorene Cancer Lett 2000, 158(1):17-25. 10.1016/S0304-3835(00)00517-6 10940504
    • (2000) Cancer Lett , vol.158 , Issue.1 , pp. 17-25
    • Lanuszewska, J.1    Widlak, P.2
  • 19
    • 0032544398 scopus 로고    scopus 로고
    • Preferential binding of high mobility group 1 protein to UV-damaged DNA. Role of the COOH-terminal domain
    • 10.1074/jbc.273.38.24730 9733773
    • Pasheva EA Pashev IG Favre A Preferential binding of high mobility group 1 protein to UV-damaged DNA. Role of the COOH-terminal domain J Biol Chem 1998, 273(38):24730-24736. 10.1074/jbc.273.38.24730 9733773
    • (1998) J Biol Chem , vol.273 , Issue.38 , pp. 24730-24736
    • Pasheva, E.A.1    Pashev, I.G.2    Favre, A.3
  • 20
    • 0033578010 scopus 로고    scopus 로고
    • Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins
    • 10.1038/21460 10385126
    • Ohndorf UM Rould MA He Q Pabo CO Lippard SJ Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins Nature 1999, 399(6737):708-712. 10.1038/21460 10385126
    • (1999) Nature , vol.399 , Issue.6737 , pp. 708-712
    • Ohndorf, U.M.1    Rould, M.A.2    He, Q.3    Pabo, C.O.4    Lippard, S.J.5
  • 21
    • 0032823310 scopus 로고    scopus 로고
    • The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2
    • 84623 10490593
    • Aidinis V Bonaldi T Beltrame M Santagata S Bianchi ME Spanopoulou E The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2 Mol Cell Biol 1999, 19(10):6532-6542. 84623 10490593
    • (1999) Mol Cell Biol , vol.19 , Issue.10 , pp. 6532-6542
    • Aidinis, V.1    Bonaldi, T.2    Beltrame, M.3    Santagata, S.4    Bianchi, M.E.5    Spanopoulou, E.6
  • 22
    • 0030994385 scopus 로고    scopus 로고
    • Stimulation of V(D)J cleavage by high mobility group proteins
    • 1169877 9184213 10.1093/emboj/16.10.2665
    • van Gent DC Hiom K Paull TT Gellert M Stimulation of V(D)J cleavage by high mobility group proteins EMBO J 1997, 16(10):2665-2670. 1169877 9184213 10.1093/emboj/16.10.2665
    • (1997) EMBO J , vol.16 , Issue.10 , pp. 2665-2670
    • van Gent, D.C.1    Hiom, K.2    Paull, T.T.3    Gellert, M.4
  • 23
    • 0030980386 scopus 로고    scopus 로고
    • V(D)J recombination: Modulation of RAG1 and RAG2 cleavage activity on 12/ 23 substrates by whole cell extract and DNA-bending proteins
    • 2196333 9166431 10.1084/jem.185.11.2025
    • Sawchuk DJ Weis-Garcia F Malik S Besmer E Bustin M Nussenzweig MC Cortes P V(D)J recombination: Modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins J Exp Med 1997, 185(11):2025-2032. 2196333 9166431 10.1084/jem.185.11.2025
    • (1997) J Exp Med , vol.185 , Issue.11 , pp. 2025-2032
    • Sawchuk, D.J.1    Weis-Garcia, F.2    Malik, S.3    Besmer, E.4    Bustin, M.5    Nussenzweig, M.C.6    Cortes, P.7
  • 24
    • 43749118207 scopus 로고    scopus 로고
    • V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies
    • 10.1074/jbc.M710301200 18187418
    • Zhang M Swanson PC V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies J Biol Chem 2008, 283(11):6717-6727. 10.1074/jbc.M710301200 18187418
    • (2008) J Biol Chem , vol.283 , Issue.11 , pp. 6717-6727
    • Zhang, M.1    Swanson, P.C.2
  • 25
    • 0036839614 scopus 로고    scopus 로고
    • A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals
    • 134746 12391148 10.1128/MCB.22.22.7790-7801.2002
    • Swanson PC A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals Mol Cell Biol 2002, 22(22):7790-7801. 134746 12391148 10.1128/MCB.22.22.7790-7801.2002
    • (2002) Mol Cell Biol , vol.22 , Issue.22 , pp. 7790-7801
    • Swanson, P.C.1
  • 26
    • 24744446820 scopus 로고    scopus 로고
    • Both high mobility group (HMG)-boxes and the acidic tail of HMGB1 regulate recombination-activating gene (RAG)-mediated recombination signal synapsis and cleavage in vitro
    • 10.1074/jbc.M503063200 15994314
    • Bergeron S Madathiparambil T Swanson PC Both high mobility group (HMG)-boxes and the acidic tail of HMGB1 regulate recombination-activating gene (RAG)-mediated recombination signal synapsis and cleavage in vitro J Biol Chem 2005, 280(35):31314-31324. 10.1074/jbc.M503063200 15994314
    • (2005) J Biol Chem , vol.280 , Issue.35 , pp. 31314-31324
    • Bergeron, S.1    Madathiparambil, T.2    Swanson, P.C.3
  • 27
    • 42449117574 scopus 로고    scopus 로고
    • HMG-box domain stimulation of RAG1/2 cleavage activity is metal ion dependent
    • 2324110 18380906 10.1186/1471-2199-9-32
    • Kriatchko AN Bergeron S Swanson PC HMG-box domain stimulation of RAG1/2 cleavage activity is metal ion dependent BMC Mol Biol 2008, 9:32. 2324110 18380906 10.1186/1471-2199-9-32
    • (2008) BMC Mol Biol , vol.9 , pp. 32
    • Kriatchko, A.N.1    Bergeron, S.2    Swanson, P.C.3
  • 29
    • 45549101973 scopus 로고    scopus 로고
    • Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition
    • 10.1038/ni.1614 18500346
    • Wang X Xiao G Zhang Y Wen X Gao X Okada S Liu X Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition Nat Immunol 2008, 9(7):794-801. 10.1038/ni.1614 18500346
    • (2008) Nat Immunol , vol.9 , Issue.7 , pp. 794-801
    • Wang, X.1    Xiao, G.2    Zhang, Y.3    Wen, X.4    Gao, X.5    Okada, S.6    Liu, X.7
  • 30
    • 33745186676 scopus 로고    scopus 로고
    • RAG and HMGB1 proteins: Purification and biochemical analysis of recombination signal complexes
    • 10.1016/S0076-6879(06)08032-3 16793390
    • Bergeron S Anderson DK Swanson PC RAG and HMGB1 proteins: Purification and biochemical analysis of recombination signal complexes Methods Enzymol 2006, 408:511-528. 10.1016/S0076-6879(06)08032-3 16793390
    • (2006) Methods Enzymol , vol.408 , pp. 511-528
    • Bergeron, S.1    Anderson, D.K.2    Swanson, P.C.3
  • 31
    • 33745055972 scopus 로고    scopus 로고
    • Identification and characterization of a gain-of-function RAG-1 mutant
    • 1489120 16738334 10.1128/MCB.02487-05
    • Kriatchko AN Anderson DK Swanson PC Identification and characterization of a gain-of-function RAG-1 mutant Mol Cell Biol 2006, 26(12):4712-4728. 1489120 16738334 10.1128/MCB.02487-05
    • (2006) Mol Cell Biol , vol.26 , Issue.12 , pp. 4712-4728
    • Kriatchko, A.N.1    Anderson, D.K.2    Swanson, P.C.3


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