Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence

Journal of Animal Science

Volumn 79, Issue 3, 2001, Pages 714-721

  Bassaganya Riera, J ^a   Hontecillas Magarzo, R ^a   Bregendahl, K ^a   Wannemuehler, M J ^a   Zimmerman, D R ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

CD8+ Lymphocytes; Cell Mediated Immunity; Immunomodulators; Linoleic Acid; Pigs

Indexed keywords

ANIMALIA; SUS SCROFA;

LINOLEIC ACID;

ANIMAL; ANIMAL FOOD; ANIMAL HOUSING; ARTICLE; BODY COMPOSITION; FAT INTAKE; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LEUKOCYTE COUNT; LYMPHOCYTE; PHENOTYPE; PHYSIOLOGY; STANDARD; SUCKLING; SWINE; UREA NITROGEN BLOOD LEVEL; WEANING;

ANIMAL FEED; ANIMALS; ANIMALS, SUCKLING; BLOOD UREA NITROGEN; BODY COMPOSITION; DIETARY FATS; HOUSING, ANIMAL; LEUKOCYTE COUNT; LINOLEIC ACID; LYMPHOCYTES; PHENOTYPE; SWINE; WEANING;

EID: 0035293879     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/2001.793714x     Document Type: Article

References (26)

1. AOAC. 1990. Official Methods of Analysis. 15th ed. Association of Official Analytical Chemists, Arlington, VA.
2. Bassaganya, J., R. Hontecillas, K. Bregendahl, M. J. Wannemuehler, and D. R. Zimmerman. 1999. Dietary conjugated linoleic acid increases CD8 T lymphocyte subpopulation in weanling pigs. J. Anim. Sci. 77(Suppl. 1):119(Abstr.).
3. Belury, M. A., and A. Kempa-Steczko. 1997. Conjugated linoleic acid modulates hepatic lipid composition in mice. Lipids 32:199-204.
4. Chew, B. P., T. S. Wong, T. D. Shultz, and N. S. Magnuson. 1997. Effects of conjugated dienoic derivatives of linoleic acid and β-carotene in modulating lymphocyte and macrophage function. Anticancer Res. 17:1099-1106.
5. Cook, M. E., D. L. Jerome, M. W. Pariza, and S. Schmidt. 1998. The pathology, hemathology and blood chemistry of pigs fed conjugated linoleic acid synthesized from sunflower oil. In: Proc. 89th Am. Oil Chemists Soc. Symp., Chicago, IL. p 21.
6. Cook, M. E., C. C. Miller, Y. Park, and M. W. Pariza. 1993. Immune modulation by altered nutrient metabolism: nutritional control of immune-induced growth depression. Poult. Sci. 72:1301-1305.
7. Dunshea, F. R., E. Ostrwska, M. Muralitharan, R. Cross, D. E. Bauman, M. W. Pariza, and C. Skarie. 1998. Dietary conjugated linoleic acid decreases backfat in finisher gilts. J. Anim. Sci. 76(Suppl. 1):131(Abstr.).
8. Eggert, J. M., A. L. Carroll, B. T. Richert, D. E. Gerrard, J. C. Forrest, B. C. Bowker, E. J. Wynvee, J. E. Hammelma, and A. P. Schinckel. 1999. Effects of conjugated linoleic acid (CLA) on the growth, carcass composition and pork quality of two genotypes of lean gilts. J. Anim. Sci. 77(Suppl. 1):178(Abstr.).
9. Goldyne, M. E., and J. D. Strobo. 1982. Human monocytes synthesize eicosanoids from T lymphocytes derived from arachidonic acid. Prostaglandins 24:623-631.
10. Ha, Y. L., J., Storkson, and M. W. Pariza. 1990. Inhibition of benzo(a-)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. Cancer Res. 50:1097-1101.
11. Hayek, M. G., S. N. Han, D. Wu, B. A. Watkins, M. Meydani, J. L. Dorsey, D. E. Smith, and S. N. Meydani. 1999. Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. J. Nutr. 129:32-38.
12. Houseknecht, K. L., J. P. Vanden Heuvel, S. Y. Moya-Camarena, C. P. Portocarrero, L. W. Peck, K. P. Nickel, and M. A. Belury. 1998. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem. Biophys. Res. Commun. 244:678-682.
13. Ip, C., and J. A. Scimeca. 1997. Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis. Nutr. Cancer 27:131-135.
14. Lee, K. N., D. Kritchevsky, and M. W. Pariza. 1994. Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis 108:19-25.
15. Marsh, W. H., B. Fingerhut, and H. Miller. 1965. Automated and manual direct methods for the determination of blood urea. Clin. Chem. 11:624-627.
16. Miller, C. C., Y. Park, M. W. Pariza, and M. E. Cook. 1994. Feeding conjugated linoleic acid to animals partially overcomes catabolic response due to endotoxin injection. Biochem. Biophys. Res. Commun. 198:1107-1112.
17. Moya-Camarena, S. Y., J. P. Vanden Heuvel, and M. A. Belury. 1999. Conjugated linoleic acid activates peroxisome proliferator-activated receptor α and β subtypes but does not induce hepatic peroxisome proliferation in Sprague-Dawley rats. Biochim. Biophys. Acta 1436:331-342.
18. Nicolosi, R. J., K. V. Courtemanche, L. Laitinen, J. A. Scimeca, and P. J. Huth. 1993. Effect of feeding diets enriched in conjugated linoleic acid on lipoproteins and aortic atherogenesis in hamsters. Circulation 88:2458(Abstr.).
19. NRC. 1988. Nutrient Requirements of Swine. National Academy Press, Washington, DC.
20. Pariza, M. W. 1991. A new cancer inhibitor in dairy products. Bull. Int. Dairy Fed. 257:29-30.
21. Ricote, M., A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass. 1998. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature (Lond.) 391:79-82.
22. Roitt, I., J. Brostoff, and D. Male. 1998. Immunology. 5th ed. Mosby International Publishers Ltd., London.
23. Sparks, J. C., B. R. Wiegand, F. C. Parrish, and D. R. Zimmerman. 1999. Effects of length of feeding conjugated linoleic acid (CLA) on growth and body composition of pigs. J. Anim. Sci. 77(Suppl. 1):178(Abstr.).
24. Su, C. G., X. Wen, S. T. Bailey, W. Jiang, S. M. Rangwala, S. A. Keilbaugh, A. Flanigan, S. Murthy, M. A. Lazar, and G. D. Wu. 1999. A novel therapy for colitis utilizing PPAR-γ ligands to inhibit inflammatory response. J. Clin. Investig. 104:383-389.
25. Sugano, M., A. Tsujita, M. Yamasaki, M. Noguchi, and K. Yamada. 1998. Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids 33:521-527.
26. Wong, M. W., B. P. Chew, T. S. Wong, H. L. Hosick, T. D. Boylston, and T. D. Shultz. 1997. Effects of dietary conjugated linoleic acid on lymphocyte function and growth of mammary tumors in mice. Anticancer Res. 17:987-994.