Wound repair

Equine Surgery

Volumn , Issue , 2006, Pages 44-62

  Theoret, Christine L ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 64049115382     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B1-41-600123-9/50007-3     Document Type: Chapter

References (127)

1. Lipowitz AJ Tissue regeneration. Textbook of Small Animal Surgery 1985, vol 1. WB Saunders, Philadelphia.
2. Wilmink JM, van Herten J, van Weeren PR, et al. Retrospective study of primary intention healing and sequestrum formation in horses compared to ponies under clinical circumstances. Equine Vet J 2002, 34:270.
3. Singer AJ, Clark RAF Cutaneous wound healing. N Engl J Med 1999, 341:738-746.
4. Simpson DM, Ross R The neutrophilic leukocyte in wound repair: A study with antineutrophil serum. J Clin Invest 1972, 51:2009.
5. Leibovitch SJ, Ross R The role of the macrophage in wound repair: A study with hydrocortisone and antimacrophage serum. Am J Pathol 1975, 78:71.
6. Martin P, D'Souza D, Martin J, et al. Wound healing in the PU.1 null mouse: Tissue repair is not dependent on inflammatory cells. Curr Biol 2003, 13:1122.
7. Smith PD, Kuhn MA, Franz MG, et al. Initiating the inflammatory phase of incisional healing prior to tissue injury. J Surg Res 2000, 92:11.
8. Molan PC The role of honey in the management of wounds. J Wound Care 1999, 8:415.
9. Swaim SF, Bohling MW Mise au point sur les récents développements en gestion de plaies chez les animaux de compagnie. Med Vet QC 2003, 33:99.
10. Wilmink JM, van Weeren PR, Stolk PW, et al. Differences in second-intention wound healing between horses and ponies: Histological aspects. Equine Vet J 1999, 31:61.
11. Wilmink JM, Veenman JN, van den Boom R, et al. Differences in polymorphonucleocyte function and local inflammatory response between horses and ponies. Equine Vet J 2003, 35:561.
12. Wilson DA, Adelstein EH, Keegan KG, et al. In vitro and in vivo effects of activated macrophage supernatant on distal limb wounds of ponies. Am J Vet Res 1996, 57:1220.
13. Wilmink JM, Stolk PW, van Weeren PR, et al. The effectiveness of the haemodialysate Solcoseryl for second-intention wound healing in horses and ponies. J Vet Med A Physiol Pathol Clin Med 2000, 47:311.
14. Engelen M, Besche B, Lefay MP, et al. Effects of ketanserin on hypergranulation tissue formation, infection, and healing of equine lower limb wounds. Can Vet J 2004, 45:144.
15. Greenhalgh DG The role of apoptosis in wound healing. Int J Biochem Cell Biol 1998, 30:1019.
16. Mignatti P, Rifkin DB, Welgus HG, et al. Proteinases and tissue remodeling. The Molecular and Cellular Biology of Wound Repair 1996, Plenum Press, New York. ed 2. R.A.F. Clark (Ed.).
17. Desmoulière A, Redard M, Darby I, et al. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 1995, 146:56.
18. Luo S, Benathan M, Raffoul W, et al. Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions. Plast Reconstr Surg 2001, 107:87.
19. Chvapil M, Pfister T, Escalada S, et al. Dynamics of the healing of skin wounds in the horse as compared with the rat. Exp Mol Pathol 1979, 30:349.
20. Jacobs KA, Leach DH, Fretz PB, et al. Comparative aspects of the healing of excisional wounds on the leg and body of horses. Vet Surg 1984, 13:83.
21. Bacon Miller C, Wilson DA, Keegan KG, et al. Growth characteristics of fibroblasts isolated from the trunk and distal aspect of the limb of horses and ponies. Vet Surg 2000, 29:1.
22. Martson M, Viljanto J, Laippala P, et al. Cranio-caudal differences in granulation tissue formation: An experimental study in the rat. Wound Repair Regen 1999, 7:119.
23. Sayah DN, Soo C, Shaw WW, et al. Downregulation of apoptosis-related genes in keloid tissues. J Surg Res 1999, 87:209.
24. Lepault É, Céleste CJ, Doré M, et al: Comparative study on microvascular occlusion and apoptosis in normal and pathologic wounds in the horse, Wound Repair Regen 2004 [submitted].
25. Ducharme-Desjarlais M, Céleste CJ, Lepault É, et al. Effect of a silicone-containing dressing on exuberant granulation tissue formation and wound repair in the horse. Am J Vet Res 2005, [in press].
26. Liekens S, De Clerq E, Neyts J Angiogenesis: Regulators and clinical applications. Biochem Pharmacol 2001, 61:253.
27. Li J, Zhang YP, Kirsner RS Angiogenesis in wound repair: Angiogenic growth factors and the extracellular matrix. Microsc Res Tech 2003, 60:107.
28. Zhu WH, Guo X, Villaschi S, et al. Regulation of vascular growth and regression by matrix metalloproteinases in the rat aorta model of angiogenesis. Lab Invest 2000, 80:545.
29. Falanga V Chronic wounds: Pathophysiologic and experimental considerations. J Invest Dermatol 1993, 100:721.
30. Stenn KS, Malhotra R Epithelialization. Wound Healing: Biochemical and Clinical Aspects 1992, WB Saunders, Philadelphia. I.K. Cohen, R.F. Diegelmann, W.J. Lindblad (Eds.).
31. Stashak TS Chapter 1. Equine Wound Management 1991, Lea & Febiger, Philadelphia. T.S. Stashak (Ed.).
32. Nanney LB, King LE Epidermal growth factor and transforming growth factorα. The Molecular and Cellular Biology of Wound Repair 1996, Plenum Press, New York. ed 2. R.A.F. Clark (Ed.).
33. LePoole IC, Boyce ST Keratinocytes suppress TGFβ1 expression by fibroblasts in cultured skin substitutes. Br J Dermatol 1999, 140:409.
34. Knottenbelt DC Equine wound management: Are there significant differences in healing at different sites on the body?. Vet Dermatol 1997, 8:273.
35. Dart AJ, Cries L, Jeffcott LB, et al. Effects of 25% propylene glycol hydrogel (Solugel) on second intention wound healing in horses. Vet Surg 2002, 31:309.
36. Burling K, Seguin MA, Marsh P, et al. Effect of topical administration of epidermal growth factor on healing of corneal epithelial defects in horses. Am J Vet Res 2000, 61:1150.
37. Yvorchuk-St.Jean K, Gaughan E, St.Jean G, et al. Evaluation of a porous bovine collagen membrane bandage for management of wounds in horses. Am J Vet Res 1995, 56:1663.
38. Gomez JH, Schumacher J, Lauten SD, et al. Effects of 3 biologic dressings on healing of cutaneous wounds on the limbs of horses. Can J Vet Res 2004, 68:49.
39. Desmoulière A, Gabbiani G The role of the myofibroblast in wound healing and fibrocontractive diseases. The Molecular and Cellular Biology of Wound Repair 1996, Plenum Press, New York. ed 2. R.A.F. Clark (Ed.).
40. Madison JB, Gronwall RR Influence of wound shape on wound contraction in horses. Am J Vet Res 1992, 53:1575.
41. Ford TS, Schumacher J, Brumbaugh GW, et al. Effects of split-thickness and full-thickness grafts on secondary graft contraction in horses. Am J Vet Res 1992, 53:1572.
42. Grinnell F, Zhu M, Carlson MA, et al. Release of mechanical tension triggers apoptosis of human fibroblasts in a model of regressing granulation tissue. Exp Cell Res 1999, 248:608.
43. Wilmink JM, Stolk PW, Van Weeren PR, et al. Differences in second-intention wound healing between horses and ponies: Macroscopic aspects. Equine Vet J 1999, 31:53.
44. Wilmink JM, Nederbragt H, van Weeren PR, et al. Differences in wound contraction between horses and ponies: The in vitro contraction capacity of fibroblasts. Equine Vet J 2001, 33:499.
45. Cochrane CA, Pain R, Knottenbelt DC In vitro wound contraction in the horse: Differences between body and limb wounds. Wounds 2003, 15:175.
46. Schwartz AJ, Wilson DA, Keegan KG, et al. Factors regulating collagen synthesis and degradation during second-intention healing of wounds in the thoracic region and the distal aspect of the forelimb of horses. Am J Vet Res 2002, 63:1564.
47. Dart AJ, Cries L, Jeffcott LB, et al. The effect of equine recombinant growth hormone on second intention wound healing in horses. Vet Surg 2002, 31:314.
48. Witte MB, Thornton FJ, Kiyama T, et al. Metalloproteinase inhibitors and wound healing: A novel enhancer of wound strength. Surgery 1998, 124:464.
49. Yager DR, Chen SM, Ward SI, et al. Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors. Wound Repair Regen 1997, 5:23.
50. Levenson SM, Geever EF, Crowley LV, et al. The healing of rat skin wounds. Ann Surg 1965, 161:293.
51. Metcalf D The granulocyte-macrophage colony stimulating factors. Science 1985, 229:16.
52. Mann A, Breuhahn K, Schirmacher P, et al. Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing: Stimulation of keratinocyte proliferation, granulation tissue formation, and vascularization. J Invest Dermatol 2001, 117:1382.
53. Mauel S, Commandeur U, Steinbach F: Cloning of equine granulocyte-macrophage colony-stimulating-factor (eq. GM-CSF), Direct submission to GenBank ( ). genbank:AAK72108.
54. Leonard WJ Type I cytokines and interferons and their receptors. Fundamental Immunology 1999, Lippincott-Raven Press, New York. ed 4. W.E. Paul (Ed.).
55. Curran JA, Argyle DJ, Cox P, et al. Nucleotide sequence of the equine interferon gamma cDNA. DNA Seq 1994, 4:405.
56. Steinbach F, Mauel S, Beier I Recombinant equine interferons: Expression cloning and biological activity. Vet Immunol Immunopathol 2002, 84:83.
57. Ishida Y, Kondo T, Takayasu T, et al. The essential involvement of cross-talk between IFN-gamma and TGF-beta in the skin wound-healing process. J Immunol 2004, 172:1848.
58. Howard RD, McIlwraith CW, Trotter GW, Nyborg JK Cloning of equine interleukin 1 alpha and equine interleukin 1 beta and determination of their full-length cDNA sequences. Am J Vet Res 1998, 59:704.
59. Howard RD, McIlwraith CW, Trotter GW, Nyborg JK Cloning of equine interleukin 1 receptor antagonist and determination of its full-length cDNA sequence. Am J Vet Res 1998, 59:712.
60. Lin ZQ, Kondo T, Ishida Y, et al. Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice. J Leukoc Biol 2003, 73:713.
61. Mori R, Kondo T, Ohshima T, et al. MMP-1 and TIMP-1 mRNA expression were markedly increased with IL-6 and TNF-alpha treatment and remains unchanged with IL-1 beta. Burns 2003, 29:527.
62. Moyer KE, Saggers GC, Allison GM, et al. Effects of interleukin-8 on granulation tissue maturation. J Cell Physiol 2002, 193:173.
63. Moroguchi A, Ishimura K, Okano K, et al. Interleukin-10 suppresses proliferation and remodeling of extracellular matrix of cultured human skin fibroblasts. Eur Surg Res 2004, 36:39.
64. Su X, Deem Morris D, McGraw RA Cloning and characterization of gene TNFα encoding equine tumor necrosis factor alpha. Gene 1991, 107:319.
65. Igarashi A, Okochi H, Bradham DM, et al. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 1993, 4:637.
66. Grotendorst GR Connective tissue growth factor: A mediator of TGFβ action on fibroblasts. Cytokine Growth Factor Rev 1997, 8:171.
67. Blom IE, Goldschmeding R, Leask A Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?. Matrix Biol 2002, 21:473.
68. Ollivier FJ, Brooks DE, Schultz GS, et al. Connective tissue growth factor in tear film of the horse: Detection, identification and origin. Graefes Arch Clin Exp Ophthalmol 2004, 242:165. Epub Nov 28, 2003.
69. Haase I, Evans R, Pofahl R, et al. Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. J Cell Sci 2003, 116:3227.
70. Stewart F, Power CA, Lennard SN, et al. Identification of the horse epidermal growth factor (EGF) coding sequence and its use in monitoring EGF gene expression in the endometrium of the pregnant mare. J Mol Endocrinol 1994, 12:341.
71. Ono M, Okamuro K, Nakayama Y, et al. Induction of human microvascular endothelial tubular morphogenesis by human keratinocytes: Involvement of transforming growth factor-alpha. Biochem Biophys Res Commun 1992, 189:601.
72. Sorensen OE, Cowland JB, Theilgaard-Monch K, et al. Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes: A consequence of common growth factors. J Immunol 2003, 170:5583.
73. Abraham JA, Klagsbrun M Modulation of wound repair by members of the fibroblast growth factor family. The Molecular and Cellular Biology of Wound Repair 1996, Plenum Press, New York. ed 2. R.A.F. Clark (Ed.).
74. Kuwabara K, Ogawa S, Matsumoto M, et al. Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells. Proc Natl Acad Sci U S A 1995, 92:4606.
75. Taylor WR, Alexander RW Autocrine control of wound repair by insulin-like growth factor 1 in cultured endothelial cells. Am J Physiol 1993, 265:C801.
76. Ando H, Jensen PJ EGF and IGF-1 enhance keratinocyte migration. J Invest Dermatol 1993, 100:633.
77. Dunaiski V, Belford DA Contribution of circulating IGF-I to wound repair in GH-treated rats. Growth Horm IGF Res 2002, 12:381.
78. Ghahary A, Shen Q, Shen YJ, et al. Induction of transforming growth factor beta 1 by insulin-like growth factor-1 in dermal fibroblasts. J Cell Physiol 1998, 174:301.
79. Otte K, Rozell B, Gessbo A, Engstrom W Cloning and sequencing of an equine insulin-like growth factor I cDNA and its expression in fetal and adult tissues. Gen Comp Endocrinol 1996, 102:11.
80. Beer HD, Gassmann MG, Munz B, et al. Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair. J Invest Dermatol Symp Proc 2000, 5:34.
81. Werner S Keratinocyte growth factor: A unique player in epithelial repair processes. Cytokine Growth Factor Rev 1998, 9:153.
82. Robson MC, Phillips TJ, Falanga V, et al. Randomized trial of topically applied repifermin (recombinant human keratinocyte growth factor-2) to accelerate wound healing in venous ulcers. Wound Repair Regen 2001, 9:347.
83. Welter H., Bollwein H, Einspanier R: Direct submission to GenBank ( ) for Equus caballus FGF-7, 2002. genbank:AJ439891.
84. Heldin CH, Westermark B Role of platelet-derived growth factor in vivo. The Molecular and Cellular Biology of Wound Repair 1996, Plenum Press, New York. ed 2. R.A.F. Clark (Ed.).
85. Pierce GF, Vande Berg J, Rudolph R, et al. Platelet-derived growth factor-BB and transforming growth factor beta 1 selectively modulate glycosaminoglycans, collagen, and myofibroblasts in excisional wounds. Am J Pathol 1991, 138:629.
86. Haber M, Cao Z, Panjwani N, et al. Effects of growth factors (EGF, PDGF-BB and TGF-beta 1) on cultured equine epithelial cells and keratocytes: implications for wound healing. Vet Ophthalmol 2003, 6:211.
87. Saba AA, Freedman BM, Gaffield JW, et al. Topical platelet-derived growth factor enhances wound closure in the absence of wound contraction: An experimental and clinical study. Ann Plast Surg 2002, 49:62.
88. Wieman TJ, Smiell JM, Su Y Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with nonhealing diabetic ulcers: A phase III randomised, placebo-controlled, double-blind study. Diabetes Care 1998, 21:822.
89. Roberts AB, Sporn MB Transforming growth factorβ. The Molecular and Cellular Biology of Wound Repair 1996, Plenum Press, New York. ed 2. R.A.F. Clark (Ed.).
90. Chin D, Boyle GM, Parsons PG, et al. What is transforming growth factor-beta (TGF-beta)?. Br J Plast Surg 2004, 57:215.
91. Penha-Goncalves MN, Onions DE, Nicolson L Cloning and sequencing of equine transforming growth factor-beta 1 (TGF beta-1) cDNA. DNA Seq 1997, 7:375.
92. Shah M, Foreman DM, Ferguson MWJ Neutralization of TGFβ1 and TGFβ2 or exogenous addition of TGFβ3 to cutaneous rat wounds reduces scarring. J Cell Sci 1995, 108:985.
93. Desmoulière A, Geinoz A, Gabbiani F, et al. Transforming growth factor β1 induces α-smooth muscle actin expression in granulation tissue myofibroblasts in quiescent and growing cultured fibroblasts. J Cell Biol 1993, 122:103.
94. Theoret CL, Barber SM, Moyana TN, et al. Expression of transforming growth factor β1, β3, and basic fibroblast growth factor in full-thickness skin wounds of equine limbs and thorax. Vet Surg 2001, 30:269.
95. van den Boom R, Wilmink JM, O'Kane S, et al. Transforming growth factor-beta levels during second-intention healing are related to the different course of wound contraction in horses and ponies. Wound Repair Regen 2002, 10:188.
96. Theoret CL, Barber SM, Gordon JR Temporal localization of immunoreactive transforming growth factor β1 in normal equine skin and in full-thickness dermal wounds. Vet Surg 2002, 31:274.
97. De Martin I, Theoret CL Spatial and temporal expression of types I and II receptors for transforming growth factor β in normal equine skin and dermal wounds. Vet Surg 2004, 33:70.
98. Cochrane CA Models in vivo of wound healing in the horse and the role of growth factors. Vet Dermatol 1997, 8:259.
99. Theoret CL, Barber SM, Moyana TN, et al. Preliminary observations on expression of transforming growth factor β1, β3, and basic fibroblast growth factor in equine limb wounds healing normally or with proud flesh. Vet Surg 2002, 31:266.
100. Dvorak HF, Brown LF, Betmar M, et al. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995, 146:1029.
101. Howdieshell TR, Callaway D, Webb WL, et al. Antibody neutralization of vascular endothelial growth factor inhibits wound granulation tissue formation. J Surg Res 2001, 96:173.
102. Miura N, Misumi K, Kawahara K, et al: Cloning of cDNA and high-level expression of equine vascular endothelial growth factor, Direct submission to GenBank ( ). genbank:BAB20890.
103. Steel CM, Robertson ID, Thomas J, et al. Effect of topical rh-TGFβ1 on second intention wound healing in horses. Austr Vet J 1999, 77:734.
104. Ohnemusl P, von Rechenberg BV, Arvinte T, et al. Application of TGFβ3 on experimentally created circular wounds in horses. Proceedings of the 8th Annual Scientific Meeting of the European Congress of Veterinary Surgeons 1999, 28:216.
105. Crovetti G, Martinelli G, Issi M, et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apheresis Sci 2004, 30:145.
106. Carter CA, Jolly DG, Worden CE, et al. Platelet-rich plasma gel promotes differentiation and regeneration during equine wound healing. Exp Mol Pathol 2003, 74:244.
107. Peacock EE Wound Repair 1984, WB Saunders, Philadelphia. ed 3.
108. Manning TO, Monteiro-Riviere NA, Bristol DG, et al. Cutaneous laser-Doppler velocimetry in nine animal species. Am J Vet Res 1991, 52:1960.
109. Hartmann M, Jonsson K, Zederfeldt B Effect of tissue perfusion and oxygenation on accumulation of collagen in healing wounds. Eur J Surg 1992, 158:521.
110. Moy LS Management of acute wounds. Dermatol Clin 1993, 11:759.
111. Xu G, Bochaton-Piallat ML, Andreutti D, et al. Regulation of alpha-smooth muscle actin and CRBP-1 expression by retinoic acid and TGF-beta in cultured fibroblasts. J Cell Physiol 2001, 187:315.
112. Varani J, Warner RL, Gharaee-Kermani M, et al. Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol 2000, 114:480.
113. Gray M Evidence-based report card from the Center for Clinical Investigation: Does oral supplementation with vitamins A or E promote healing of chronic wounds?. J Wound Ostomy Continence Nurs 2003, 30:290.
114. Lansdown AB Zinc in the healing wound. Lancet 1996, 347:706.
115. Gray M Evidence-Based Report Card from the Center for Clinical Investigation: Does oral zinc supplementation promote healing of chronic wounds?. J Wound Ostomy Continence Nurs 2003, 30:295.
116. Abd-El-Aleem SA, Ferguson MWJ, Appleton I, et al. Expression of cyclooxygenase isoforms in normal human skin and chronic venous ulcers. J Pathol 2001, 195:616.
117. Schneiter HL, McClure JR, Cho DY, et al: The effects of flunixin meglumine on early wound healing of abdominal incisions in ponies, Vet Surg 16:101 (abstr).
118. Wilgus TA, Vodovotz Y, Vittadini E, et al. Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. Wound Repair Regen 2003, 11:25.
119. Marks JG, Cano C, Leitzel K, et al. Inhibition of wound healing by topical steroids. Dermatol Surg Oncol 1983, 9:819.
120. Hashimoto I, Nakanishi H, Shono Y, et al. Angiostatic effects of corticosteroid on wound healing of the rabbit ear. J Med Invest 2002, 49:61.
121. Beck LS, Deguzman L, Lee WP, et al. TGF-beta 1 accelerates wound healing: Reversal of steroid-impaired healing in rats and rabbits. Growth Factors 1991, 5:295.
122. Chedid M, Hoyle JR, Csaky KG, et al. Glucocorticoids inhibit keratinocyte growth factor production in primary dermal fibroblasts. Endocrinology 1996, 137:2232.
123. Barber SM Second intention wound healing in the horse: the effect of bandages and topical corticosteroids. Proc Am Assoc Equine Pract 1990, 35:107.
124. Howard RD, Stashak TS, Baxter GM Evaluation of occlusive dressings for management of full-thickness excisional wounds on the distal portion of the limbs of horses. Am J Vet Res 1993, 54:2150.
125. Berry DB, Sullins KE Effects of topical application of antimicrobials and bandaging on healing and granulation tissue formation in wounds of the distal aspect of the limbs in horses. Am J Vet Res 2003, 64:88.
126. Bigbie RB, Schumacher J, Swaim SF, et al. Effects of amnion and live yeast cell derivative on second-intention healing in horses. Am J Vet Res 1991, 52:1376.
127. Goodrich LR, Moll HD, Crisman MV, et al. Comparison of equine amnion and a nonadherent wound dressing material for bandaging pinch-grafted wounds in ponies. Am J Vet Res 2000, 61:326.