In vitro and in vivo effects of activated macrophage supernatant on distal limb wounds of ponies

American Journal of Veterinary Research

Volumn 57, Issue 8, 1996, Pages 1225-1227

  Wilson, D A ^a   Adelstein, E H ^b   Keegan, K G ^a   Barrett, B A ^b   Kutz Jr , R R ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; EQUIDAE; ORYCTOLAGUS CUNICULUS;

EID: 3043001133     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Walton GS, Neal PA. Observations on wound healing in the horse: the role of wound contraction. Equine Vet J 1972;4:93-97.
2. Jacobs KA, Leach DH, Fretz PB, et al. Comparative aspects of the healing of excisional wounds on the leg and body of horses. Vet Surg 1984;13:83-90.
3. Lees MJ, Fretz PB, Bailey JV, et al. Second-intention wound healing. Compend Contin Educ Pract Vet 1989;11(7):857-865.
4. Fretz PB, Marten GS, Jacobs KA, et al. Treatment of exuberant granulation tissue in the horse: evaluation of four methods. Vet Surg 1983;12:137-140.
5. Bertone AL, Sullins KE, Stashak TS, et al. Effect of wound location and the use of topical collagen gel on exuberant granulation tissue formation and wound healing in the horse and pony. Am J Vet Res 1985,46:1438-1444.
6. Bigbie RB, Schumacher J, Moll D, et al. Equine amnion as a biological dressing in the treatment of open wounds in horses, in Proceedings. Am Assoc Equine Pract 1989;35:117-125.
7. Barber SM. Second intention wound healing in the horse: the effect of bandages and topical corticosteroids, in Proceedings. Am Assoc Equine Pract 1989;35:107-116.
8. Bigbie RB, Schumacher J, Swaim SF, et al. Effects of amnion and live yeast cell derivative on second-intention healing in horses. Am J Vet Res 1991;52:1376-1382.
9. Blackford JT, Blackford LW, Adair HS. The use of an antimicrobial glucocorticosteroid ointment on granulating lower leg wounds in horses, in Proceedings. Am Assoc Equine Pract 1991;37: 71-81.
10. Howard RD, Stashak TS, Baxter GM. Evaluation of occlusive dressings for management of full-thickness excisional wounds on the distal portion of the limbs of horses. Am J Vet Res 1993;54: 2150-2154.
11. Madison JB, Hamir AN, Ehrlich HP, et al. Effects of a proprietary topical medication on wound healing and collagen deposition in horses. Am J Vet Res 1991;52:1128-1131.
12. Hancock WW, Pleau ME, Kobzik L. Recombinant granulocyte-macrophage colony-stimulating factor down-regulates expression of IL-2 receptor on human mononuclear phagocytes by induction of prostaglandin. J Immunol 1988;140:3021-3024.
13. Cromack DT, Porras-Reyes B, Mustoe TA. Current concepts in wound healing: growth factor and macrophage interaction. J Trauma 1990;30:S129-S133.
14. Renz H, Gong JH, Schmidt A, et al. Release of tumor necrosis factor-α from macrophages: enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleopeptides. J Immunol 1988;141:2388-2393.
15. Korn JH, Halushka PV, LeRoy EC. Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production. J Clin Invest 1980;65:543-554.
16. Elias JA, Rossman MD, Zurier RB, et al. Human alveolar macrophage inhibition of lung fibroblast growth: a prostaglandin-dependent process. Am Rev Respir Dis 1985;131:94-99.
17. Wahl SM. The role of lymphokines and monokines in fibrosis. Ann N Y Acad Sci 1985;460:224-231.
18. Elias JA, Jimenez SA, Freundlich B. Recombinant gamma, alpha, and beta interferon regulation of human lung fibroblast proliferation. Am Rev Respir Dis 1987;135:62-65.
19. Fotev Z, Whitaker D, Papadimitriou JM. Role of macrophages in mesothelial healing. J Pathol 1987;151:209-219.
20. Turck CW, Dohlman JG, Goetzl EJ. Immunological mediators of wound healing and fibrosis (review). J Cell Physiol 1987; Suppl 5:89-93.
21. Bryant SM, Fukasawa M, Orita H, et al. Mediation of post-surgical wound healing by macrophages. Prog Clin Biol Res 1988; 266:273-290.
22. Fukasawa M, Bryant SM, DiZerega GS. Incorporation of thymidine by fibroblasts: evidence for complex regulation by post-surgical macrophages. J Surg Res 1988;45:460-466.
23. Leibovich SJ, Wiseman DM. Macrophages, wound repair and angiogenesis (review). Prog Clin Biol Res 1988;266:131-145.
24. Rappolee DA, Mark D, Banda MJ, et al. Wound macrophages express TGF-α and other growth factors in vivo: analysis by mRNA phenotyping. Science 1988;241:708-712.
25. Knighton DR, Fiegel VD. The macrophages: effector cell wound repair (review). Prog Clin Biol Res 1989;299:217-226.
26. Steenfos HH, Hunt TK, Scheuenstuhl H, et al. Selective effects of tumor necrosis factor-alpha on wound healing in rats. Surgery 1989;106:171-176.
27. Whicher JT, Evans SW. Cytokines in disease. Clin Chem 1990;36(7):1269-1281.
28. Concannon MJ, Barrett BB, Adelstein EH, et al. The inhibition of fibroblast proliferation by a novel monokine: an in vitro and in vivo study. J Burn Care Rehabil 1993;14:141-147.
29. Kasahara K, Kobayashi K, Shikama Y, et al. The role of monokines in granuloma formation in mice: the ability of interleukin-1 and tumor necrosis factor-alpha to induce lung granulomas. Clin Immunol Immunopathol 1989;51:419-425.
30. Bennett NT, Schultz GS. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg 1993;165:728-737.
31. Gorskaia IF. Effects of IL-1 and TNF-alpha on the in vitro growth of fibroblasts. Byull Eksp Biol Med 1992;113:68-69.
32. Hamilton JA, Butler DM, Stanton H. Cytokine interactions promoting DNA synthesis in human synovial fibroblasts. J Rheumatol 1994;21:797-803.
33. Lynch SE, Colvin RB, Antoniades HN. Growth factors in wound healing: single and synergistic effects on partial thickness porcine skin wounds. J Clin Invest 1989;84:640-646.
34. Falanga V. Growth factors and wound healing. Dermatol Clin 1993;11:667-675.
35. Compensating polar planimeter, instruction manual. Morristown, NJ: Keuffel & Esser, 1963;20.
36. Analysis of variance IV: split-plot designs and analysis. In: Steel RGD, Torrie JH, eds. Principles and procedures of statistics - a biometrical approach. 2nd ed. New York: McGraw Hill Book Co, 1980;394.
37. Houck JC, Weil RL, Sharma VK. Evidence for a fibroblast chalone. Nature-New Biology 1972;240:210-211.
38. Richter KH. Investigation of the fibroblast chalone. Hoppe-Seyler's Z Physiol Chem 1978;359:1435-1439.
39. May SA, Hooke RE, Lees P. The characterisation of equine interleukin-1. Vet Immunol Immunopathol 1990;24:169-175.
40. Hunt TK, LaVan FB. Enhancement of wound healing by growth factors. N Engl J Med 1989;321:111-112.
41. Davidson JM, Broadley KN. Manipulation of the wound-healing process with basic fibroblast growth factor. Ann N Y Acad Sci 1991;638:306-315.
42. Hom DB, Maisel RH. Angiogenic growth factors: their effects and potential in soft tissue wound healing. Ann Otol Rhinol Laryngol 1992;101:349-354.