메뉴 건너뛰기




Volumn 68, Issue 1, 2009, Pages 102-110

The proapoptotic BCL-2 homology domain 3-only protein bim is not critical for acute excitotoxic cell death

Author keywords

Apoptosis; Cell death; Epilepsy; Excitotoxicity; Hippocampus; Kainic acid; Neurodegeneration

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; CASPASE 3; KAINIC ACID; AMINO ACID RECEPTOR STIMULATING AGENT; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; ENOLASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MEMBRANE PROTEIN; ONCOPROTEIN;

EID: 64049109788     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e31819385fd     Document Type: Article
Times cited : (22)

References (48)
  • 2
    • 0040449520 scopus 로고    scopus 로고
    • Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy
    • Kälviäinen R, Salmenperä T, Partanen K, et al. Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy. Neurology 1998; 50:1377-82
    • (1998) Neurology , vol.50 , pp. 1377-1382
    • Kälviäinen, R.1    Salmenperä, T.2    Partanen, K.3
  • 3
    • 0032892647 scopus 로고    scopus 로고
    • Progressive hippocampal atrophy in chronic intractable temporal lobe epilepsy
    • O'Brien TJ, So EL, Meyer FB, et al. Progressive hippocampal atrophy in chronic intractable temporal lobe epilepsy. Ann Neurol 1999;45: 526-29
    • (1999) Ann Neurol , vol.45 , pp. 526-529
    • O'Brien, T.J.1    So, E.L.2    Meyer, F.B.3
  • 5
    • 0033040857 scopus 로고    scopus 로고
    • Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment
    • Faherty CJ, Xanthoudakis S, Smeyne RJ. Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment. Brain Res Mol Brain Res 1999;70:159-63
    • (1999) Brain Res Mol Brain Res , vol.70 , pp. 159-163
    • Faherty, C.J.1    Xanthoudakis, S.2    Smeyne, R.J.3
  • 6
    • 0035019143 scopus 로고    scopus 로고
    • Caspase-2 activation is redundant during seizure-induced neuronal death
    • Henshall DC, Skradski SL, Bonislawski DP, et al. Caspase-2 activation is redundant during seizure-induced neuronal death. J Neurochem 2001; 77:886-95
    • (2001) J Neurochem , vol.77 , pp. 886-895
    • Henshall, D.C.1    Skradski, S.L.2    Bonislawski, D.P.3
  • 7
    • 0036077250 scopus 로고    scopus 로고
    • Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures
    • Henshall DC, Skradski SL, Meller R, et al. Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures. Neurobiol Dis 2002;10:71-87
    • (2002) Neurobiol Dis , vol.10 , pp. 71-87
    • Henshall, D.C.1    Skradski, S.L.2    Meller, R.3
  • 8
    • 0030614952 scopus 로고    scopus 로고
    • Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
    • Hara H, Friedlander RM, Gagliardini V, et al. Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc Natl Acad Sci U S A 1997;94:2007-12
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2007-2012
    • Hara, H.1    Friedlander, R.M.2    Gagliardini, V.3
  • 9
    • 0031442999 scopus 로고    scopus 로고
    • Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide
    • Leist M, Volbracht C, Kühnle S, et al. Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide. Mol Med 1997;3: 750-64
    • (1997) Mol Med , vol.3 , pp. 750-764
    • Leist, M.1    Volbracht, C.2    Kühnle, S.3
  • 10
    • 0034051665 scopus 로고    scopus 로고
    • Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration
    • Viswanath V, Wu Z, Fonck C, et al. Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration. Proc Natl Acad Sci U S A 2000;97:2270-75
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2270-2275
    • Viswanath, V.1    Wu, Z.2    Fonck, C.3
  • 11
    • 0035888112 scopus 로고    scopus 로고
    • Domoic acidYinduced neuronal damage in the rat hippocampus: Changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response
    • Ananth C, Thameem Dheen S, Gopalakrishnakone P, et al. Domoic acidYinduced neuronal damage in the rat hippocampus: Changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response. J Neurosci Res 2001;66:177-90
    • (2001) J Neurosci Res , vol.66 , pp. 177-190
    • Ananth, C.1    Thameem Dheen, S.2    Gopalakrishnakone, P.3
  • 13
    • 26044454554 scopus 로고    scopus 로고
    • Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans
    • Kann O, Kovács R, Njunting M, et al. Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans. Brain 2005;128:2396-407
    • (2005) Brain , vol.128 , pp. 2396-3407
    • Kann, O.1    Kovács, R.2    Njunting, M.3
  • 14
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A. The BCL-2 protein family: Opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008;9:47-59
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 15
    • 0032518787 scopus 로고    scopus 로고
    • Bim: A novel member of the Bcl-2 family that promotes apoptosis
    • O'Connor L, Strasser A, O'Reilly LA, et al. Bim: A novel member of the Bcl-2 family that promotes apoptosis. EMBO J 1998;17:384-95
    • (1998) EMBO J , vol.17 , pp. 384-395
    • O'Connor, L.1    Strasser, A.2    O'Reilly, L.A.3
  • 16
    • 0032161337 scopus 로고    scopus 로고
    • BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domaincontaining proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members
    • Hsu SY, Lin P, Hsueh AJ. BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domaincontaining proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol Endocrinol 1998;12:1432-40
    • (1998) Mol Endocrinol , vol.12 , pp. 1432-1440
    • Hsu, S.Y.1    Lin, P.2    Hsueh, A.J.3
  • 17
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999;286:1735-38
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3
  • 18
    • 0037148840 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family member bim is required for apoptosis of autoreactive thymocytes
    • Bouillet P, Purton JF, Godfrey DI, et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 2002; 415:922-26
    • (2002) Nature , vol.415 , pp. 922-926
    • Bouillet, P.1    Purton, J.F.2    Godfrey, D.I.3
  • 19
    • 0141959215 scopus 로고    scopus 로고
    • Loss of the proapoptotic BH3-only Bcl-2 family member bim inhibits BCR stimulation yinduced apoptosis and deletion of autoreactive B cells
    • Enders A, Bouillet P, Puthalakath H, et al. Loss of the proapoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulationYinduced apoptosis and deletion of autoreactive B cells. J Exp Med 2003;198: 1119-26
    • (2003) J Exp Med , vol.198 , pp. 1119-1126
    • Enders, A.1    Bouillet, P.2    Puthalakath, H.3
  • 20
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • Gilley J, Coffer PJ, Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 2003;162:613-22
    • (2003) J Cell Biol , vol.162 , pp. 613-622
    • Gilley, J.1    Coffer, P.J.2    Ham, J.3
  • 21
    • 0035053624 scopus 로고    scopus 로고
    • Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
    • Putcha GV, Moulder KL, Golden JP, et al. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 2001;29:615-28
    • (2001) Neuron , vol.29 , pp. 615-628
    • Putcha, G.V.1    Moulder, K.L.2    Golden, J.P.3
  • 22
    • 0037860975 scopus 로고    scopus 로고
    • JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
    • Putcha GV, Le S, Frank S, et al. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 2003;38:899-914
    • (2003) Neuron , vol.38 , pp. 899-914
    • Putcha, G.V.1    Le Frank, S.S.2
  • 23
    • 0036301277 scopus 로고    scopus 로고
    • Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice
    • Shibata M, Hattori H, Sasaki T, et al. Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab 2002;22: 810-20
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 810-820
    • Shibata, M.1    Hattori, H.2    Sasaki, T.3
  • 24
    • 0035049449 scopus 로고    scopus 로고
    • Dominant-negative c-Jun promotes neuronal survival by reducing bim expression and inhibiting mitochondrial cytochrome c release
    • Whitfield J, Neame SJ, Paquet L, et al. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 2001;29:629-43
    • (2001) Neuron , vol.29 , pp. 629-643
    • Whitfield, J.1    Neame, S.J.2    Paquet, L.3
  • 25
    • 33746881744 scopus 로고    scopus 로고
    • Mitochondria in DRG neurons undergo hyperglycemic mediated injury through bim, bax and the fission protein Drp1
    • Leinninger GM, Backus C, Sastry AM, et al. Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiol Dis 2006;23:11-22
    • (2006) Neurobiol Dis , vol.23 , pp. 11-22
    • Leinninger, G.M.1    Backus, C.2    Sastry, A.M.3
  • 26
    • 36348989734 scopus 로고    scopus 로고
    • Puma is a dominant regulator of oxidative stress induced bax activation and neuronal apoptosis
    • Steckley D, Karajgikar M, Dale L, et al. Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis. J Neurosci 2007;27:12989-99
    • (2007) J Neurosci , vol.27 , pp. 12989-12999
    • Steckley, D.1    Karajgikar, M.2    Dale, L.3
  • 27
    • 11144355911 scopus 로고    scopus 로고
    • Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy
    • Shinoda S, Schindler CK, Meller R, et al. Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest 2004;113:1059-68
    • (2004) J Clin Invest , vol.113 , pp. 1059-1068
    • Shinoda, S.1    Schindler, C.K.2    Meller, R.3
  • 28
    • 41549135942 scopus 로고    scopus 로고
    • FoxO transcription factors in the maintenance of cellular homeostasis during aging
    • Salih DA, Brunet A. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr Opin Cell Biol 2008;20:126-36
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 126-136
    • Salih, D.A.1    Brunet, A.2
  • 30
    • 0141836884 scopus 로고    scopus 로고
    • Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acidmediated neuronal death in the rat brain
    • Korhonen L, Belluardo N, Mudo G, et al. Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acidmediated neuronal death in the rat brain. Eur J Neurosci 2003;18:1121-34
    • (2003) Eur J Neurosci , vol.18 , pp. 1121-1134
    • Korhonen, L.1    Belluardo, N.2    Mudo, G.3
  • 31
    • 33646849420 scopus 로고    scopus 로고
    • Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus
    • Heinrich C, Nitta N, Flubacher A, et al. Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus. J Neurosci 2006;26:4701-13
    • (2006) J Neurosci , vol.26 , pp. 4701-4713
    • Heinrich, C.1    Nitta, N.2    Flubacher, A.3
  • 32
    • 0036813472 scopus 로고    scopus 로고
    • Activation of Bcl-2- associated death protein and counter-response of akt within cell populations during seizure-induced neuronal death
    • Henshall DC, Araki T, Schindler CK, et al. Activation of Bcl-2- associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death. J Neurosci 2002; 22:8458-65
    • (2002) J Neurosci , vol.22 , pp. 8458-8465
    • Henshall, D.C.1    Araki, T.2    Schindler, C.K.3
  • 33
    • 0028893653 scopus 로고
    • Morphogenetic effect of kainite on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor
    • Suzuki F, Junier MP, Guilhem D, et al. Morphogenetic effect of kainite on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor. Neuroscience 1995;64:665-74
    • (1995) Neuroscience , vol.64 , pp. 665-674
    • Suzuki, F.1    Junier, M.P.2    Guilhem, D.3
  • 34
    • 0028939689 scopus 로고
    • The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy
    • Mathern GW, Babb TL, Vickrey BG, et al. The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy. Brain 1995;118:105-18
    • (1995) Brain , vol.118 , pp. 105-118
    • Mathern, G.W.1    Babb, T.L.2    Vickrey, B.G.3
  • 35
    • 0343593734 scopus 로고    scopus 로고
    • Changes in the distribution and connectivity of interneurons in the epileptic human dentate gyrus
    • Maglóczky Z, Wittner L, Borhegyi Z, et al. Changes in the distribution and connectivity of interneurons in the epileptic human dentate gyrus. Neuroscience 2000;96:7-25
    • (2000) Neuroscience , vol.96 , pp. 7-25
    • Maglóczky, Z.1    Wittner, L.2    Borhegyi, Z.3
  • 36
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: A molecular perspective
    • Seifert G, Schilling K, Steinhäuser C. Astrocyte dysfunction in neurological disorders: A molecular perspective. Nat Rev Neurosci 2006;7: 194-206
    • (2006) Nat Rev Neurosci , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhäuser, C.3
  • 37
    • 38649087981 scopus 로고    scopus 로고
    • Modulators of neuronal cell death in epilepsy
    • Henshall DC, Murphy BM. Modulators of neuronal cell death in epilepsy. Curr Opin Pharmacol 2008;8:75-81
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 75-81
    • Henshall, D.C.1    Murphy, B.M.2
  • 38
    • 33846915925 scopus 로고    scopus 로고
    • Kainic acid induces early and transient autophagic stress in mouse hippocampus
    • Shacka JJ, Lu J, Xie ZL, et al. Kainic acid induces early and transient autophagic stress in mouse hippocampus. Neurosci Lett 2007;414:57-60
    • (2007) Neurosci Lett , vol.414 , pp. 57-60
    • Shacka, J.J.1    Lu, J.2    Xie, Z.L.3
  • 39
    • 34249805412 scopus 로고    scopus 로고
    • Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain
    • Niquet J, Auvin S, Archie M, et al. Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain. Epilepsia 2007;48: 1203-6
    • (2007) Epilepsia , vol.48 , pp. 1203-1206
    • Niquet, J.1    Auvin, S.2    Archie, M.3
  • 41
    • 0034085349 scopus 로고    scopus 로고
    • Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: Implication for programmed cell death mechanisms
    • Fujikawa DG, Shinmei SS, Cai B. Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: Implication for programmed cell death mechanisms. Neuroscience 2000; 98:41-53
    • (2000) Neuroscience , vol.98 , pp. 41-53
    • Fujikawa, D.G.1    Shinmei, S.S.2    Cai, B.3
  • 42
    • 34250758642 scopus 로고    scopus 로고
    • ER stress triggers apoptosis by activating BH3-only protein bim
    • Puthalakath H, O'Reilly LA, Gunn P, et al. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 2007;129:1337-49
    • (2007) Cell , vol.129 , pp. 1337-1349
    • Puthalakath, H.1    O'Reilly, L.A.2    Gunn, P.3
  • 43
    • 23044514254 scopus 로고    scopus 로고
    • Regulatory phosphorylation of bim: Sorting out the ERK from the JNK
    • Ley R, Ewings KE, Hadfield K, et al. Regulatory phosphorylation of Bim: Sorting out the ERK from the JNK. Cell Death Differ 2005;12: 1008-14
    • (2005) Cell Death Differ , vol.12 , pp. 1008-1014
    • Ley, R.1    Ewings, K.E.2    Hadfield, K.3
  • 44
    • 33646376225 scopus 로고    scopus 로고
    • Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons
    • Meller R, Cameron JA, Torrey DJ, et al. Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. J Biol Chem 2006;281:7429-36
    • (2006) J Biol Chem , vol.281 , pp. 7429-7436
    • Meller, R.1    Cameron, J.A.2    Torrey, D.J.3
  • 45
    • 33644840364 scopus 로고    scopus 로고
    • Models of epilepsy in the developing and adult brain: Implications for neuroprotection
    • Stafstrom C, Sutula T. Models of epilepsy in the developing and adult brain: Implications for neuroprotection. Epilepsy Behav 2005;7 (suppl 3):S18-24
    • (2005) Epilepsy Behav , vol.7 , Issue.SUPPL.3
    • Stafstrom, C.1    Sutula, T.2
  • 46
    • 0347091260 scopus 로고    scopus 로고
    • BAK alters neuronal excitability and can switch from antito pro-death function during postnatal development
    • Fannjiang Y, Kim CH, Huganir RL, et al. BAK alters neuronal excitability and can switch from antito pro-death function during postnatal development. Dev Cell 2003;4:575-85
    • (2003) Dev Cell , vol.4 , pp. 575-585
    • Fannjiang, Y.1    Ch, K.2    Huganir, R.L.3
  • 47
    • 0141856430 scopus 로고    scopus 로고
    • Modulation of synaptic transmission by the BCL-2 family protein BCL-xL
    • Jonas EA, Hoit D, Hickman JA, et al. Modulation of synaptic transmission by the BCL-2 family protein BCL-xL. J Neurosci 2003; 23:8423-31
    • (2003) J Neurosci , vol.23 , pp. 8423-8431
    • Jonas, E.A.1    Hoit, D.2    Hickman, J.A.3
  • 48
    • 0031762952 scopus 로고    scopus 로고
    • Trophic support promotes survival of bcl-xYdeficient telencephalic cells in vitro
    • Shindler KS, Yunker AM, Cahn R, et al. Trophic support promotes survival of bcl-xYdeficient telencephalic cells in vitro. Cell Death Differ 1998;5:901-10
    • (1998) Cell Death Differ , vol.5 , pp. 901-910
    • Shindler, K.S.1    Yunker, A.M.2    Cahn, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.