Growth inhibitory activity of a novel lectin from Cliona varians against K562 human erythroleukemia cells

Cancer Chemotherapy and Pharmacology

Volumn 63, Issue 6, 2009, Pages 1023-1033

  Queiroz, Alexandre F S ^a   Silva, Rodrigo A ^b   Moura, Raniere M ^a   Dreyfuss, Juliana L ^c   Paredes Gamero, Edgar J ^c   Souza, Ana C S ^b   Tersariol, Ivarne L S ^c,d   Santos, Elizeu A ^a   Nader, Helena B ^c   Justo, Giselle Z ^c   De Sales, Maurício P ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

Author keywords

Antitumor; Apoptosis; Cathepsin B; Cliona varians; Cytotoxicity; K562; Lectin

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CASPASE; CATHEPSIN B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LECTIN; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PROTEIN P21; PROTEINASE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLOOD; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL DEATH; CELL STRAIN JUR KAT; CELL STRAIN K562; CLIONA VARIANS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROLEUKEMIA CELL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IMMUNOBLOTTING; LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SOLID TUMOR; SPONGE (PORIFERA); STAINING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; CLIONE; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; INHIBITORY CONCENTRATION 50; JURKAT CELLS; K562 CELLS; LECTINS; LYMPHOCYTES;

EID: 63949087045     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0825-4     Document Type: Article

References (45)

1. LE Broker FA Kruyt G Giaccone 2005 Cell death independent of caspases: a review Clin Cancer Res 11 3155 3162
2. N Fehrenbacher M Jaattela 2005 Lysosomes as targets for cancer therapy Cancer Res 65 2993 2995
3. ME Guicciardi M Leist GJ Gores 2004 Lysosomes in cell death Oncogene 23 2881 2890
4. N Sharon 1984 Carbohydrates as recognition determinants in phagocytosis and in lectin-mediated killing of target cells Biol Cell 51 2 239 245
5. FI Abdullaev EG de Mejia 1997 Antitumor effect of plant lectins Nat Toxins 5 157 163
6. AM Atta M Barralnetto S Peixinho MLB Sousaatta 1989 Isolation and functional-characterization of a mitogenic lectin from the marine sponge Cinachyrella alloclada Braz J Med Biol Res 22 379 385
7. T Hajto K Hostanska T Berki L Palinkas F Boldizsar P Nemeth 2005 Oncopharmacological perspectives of a plant lectin (Viscum album agglutinin-I): overview of recent results from in vitro experiments and in vivo animal models, and their possible relevance for clinical applications Evid Based Complement Alternat Med 2 59 67
8. H Wang TB Ng VE Ooi WK Liu 2000 Effects of lectins with different carbohydrate-binding specificities on hepatoma, choriocarcinoma, melanoma and osteosarcoma cell lines Int J Biochem Cell Biol 32 365 372
9. MI Arenas E Romo I de Gaspar FR de Bethencourt M Sanchez-Chapado B Fraile R Paniagua 1999 A lectin histochemistry comparative study in human normal prostate, benign prostatic hyperplasia, and prostatic carcinoma Glycoconj J 16 375 382
10. E Gorelik U Galili A Raz 2001 On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis Cancer Metastasis Rev 20 245 277
11. MM Opric S Poznanovic Z Kljajic D Sladic G Pupic B Perunovic MJ Gasic 1996 Labelling of breast carcinoma, thyroid carcinoma and melanoma with manno- and galacto-specific lectins from marine invertebrates Eur J Histochem 40 211 218
12. H Bantel IH Engels W Voelter K Schulze-Osthoff S Wesselborg 1999 Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis Cancer Res 59 2083 2090
13. N Miyoshi Y Koyama Y Katsuno S Hayakawa T Mita T Ohta K Kaji M Isemura 2001 Apoptosis induction associated with cell cycle dysregulation by rice bran agglutinin J Biochem (Tokyo) 130 799 805
14. H Ohba S Moriwaki R Bakalova S Yasuda N Yamasaki 2004 Plant-derived abrin-a induces apoptosis in cultured leukemic cell lines by different mechanisms Toxicol Appl Pharmacol 195 182 193
15. R Park MS Kim HS So BH Jung SR Moon SY Chung CB Ko BR Kim HT Chung 2000 Activation of c-Jun N-terminal kinase 1 (JNK1) in mistletoe lectin II-induced apoptosis of human myeloleukemic U937 cells Biochem Pharmacol 60 1685 1691
16. TJ Yoon YC Yoo TB Kang K Shimazaki SK Song KH Lee SH Kim CH Park I Azuma JB Kim 1999 Lectins isolated from Korean mistletoe (Viscum album coloratum) induce apoptosis in tumor cells Cancer Lett 136 33 40
17. K Inamori T Saito D Iwaki T Nagira S Iwanaga F Arisaka S Kawabata 1999 A newly identified horseshoe crab lectin with specificity for blood group A antigen recognizes specific O-antigens of bacterial lipopolysaccharides J Biol Chem 274 3272 3278
18. N Okino S Kawabata T Saito M Hirata T Takagi S Iwanaga 1995 Purification, characterization, and cDNA cloning of a 27-kDa lectin (L10) from horseshoe crab hemocytes J Biol Chem 270 31008 31015
19. I Pajic Z Kljajic N Dogovic D Sladic Z Juranic MJ Gasic 2002 A novel lectin from the sponge Haliclona cratera: isolation, characterization and biological activity Comp Biochem Physiol C Toxicol Pharmacol 132 213 221
20. HC Schroder Z Kljajic R Wegner P Reuter M Gasic G Uhlenbruck B Kurelac WEG Muller 1990 The galactose-specific lectin from the sponge Chondrilla nucula displays anti-human immunodeficiency virus activity in vitro via stimulation of the (2'-5') oligoadenylate metabolism Antivir Chem Chemother 1 2 99 105
21. Y Fukuda T Sugahara M Ueno Y Fukuta Y Ochi K Akiyama T Miyazaki S Masuda A Kawakubo K Kato 2006 The anti-tumor effect of Euchema serra agglutinin on colon cancer cells in vitro and in vivo Anticancer Drugs 17 943 947
22. RM Moura AF Queiroz JM Fook AS Dias NK Monteiro JK Ribeiro GE Moura LL Macedo EA Santos MP Sales 2006 CvL, a lectin from the marine sponge Cliona varians: isolation, characterization and its effects on pathogenic bacteria and Leishmania promastigotes Comp Biochem Physiol A Mol Integr Physiol 145 517 523
23. H Debray D Decout G Strecker G Spik J Montreuil 1981 Specificity of 12 Lectins towards oligosaccharides and glycopeptides related to N-glycosylproteins Eur J Biochem 117 41 55
24. UK Laemmli 1970 Cleavage of structural proteins during the assembly of the head of the bacteriophage T4 Nature 227 680 683
25. N Bromberg GZ Justo M Haun N Duran CV Ferreira 2005 Violacein cytotoxicity on human blood lymphocytes and effect on phosphatases J Enzyme Inhib Med Chem 20 449 454
26. DD de Carvalho FT Costa N Duran M Haun 2006 Cytotoxic activity of violacein in human colon cancer cells Toxicol In Vitro 20 1514 1521
27. ME Guicciardi J Deussing H Miyoshi SF Bronk PA Svingen C Peters SH Kaufmann GJ Gores 2000 Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c J Clin Invest 106 1127 1137
28. EF Hartree 1972 Determination of protein: a modification of the Lowry method that gives a linear photometric response Anal Biochem 48 422 427
29. L Foghsgaard D Wissing D Mauch U Lademann L Bastholm M Boes F Elling M Leist M Jaattela 2001 Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor J Cell Biol 153 999 1010
30. IS Mathiasen CM Hansen L Foghsgaard M Jaattela 2001 Sensitization to TNF-induced apoptosis by 1, 25-dihydroxy vitamin D(3) involves up-regulation of the TNF receptor 1 and cathepsin B Int J Cancer 93 224 231
31. B Turk V Stoka 2007 Protease signalling in cell death: caspases versus cysteine cathepsins FEBS Lett 581 2761 2767
32. C Nakanishi M Toi 2005 Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs Nat Rev Cancer 5 297 309
33. D Kirchner J Duyster O Ottmann RM Schmid L Bergmann G Munzert 2003 Mechanisms of Bcr-Abl-mediated NF-kappaB/Rel activation Exp Hematol 31 504 511
34. JY Reuther GW Reuther D Cortez AM Pendergast AS Baldwin Jr 1998 A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation Genes Dev 12 968 981
35. M Karin A Lin 2002 NF-kappaB at the crossroads of life and death Nat Immunol 3 221 227
36. I Sanchez-Garcia G Grutz 1995 Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2 Proc Natl Acad Sci USA 92 5287 5291
37. S Desrivieres S Volarevic L Mercep S Ferrari 1997 Evidence for different mechanisms of growth inhibition of T-cell lymphoma by phorbol esters and concanavalin A J Biol Chem 272 2470 2476
38. GV Kulkarni CA McCulloch 1995 Concanavalin A induced apoptosis in fibroblasts: the role of cell surface carbohydrates in lectin mediated cytotoxicity J Cell Physiol 165 119 133
39. GM Cragg DJ Newman SS Yang 2006 Natural product extracts of plant and marine origin having antileukemia potential. The NCI experience J Nat Prod 69 488 498
40. A McGahon R Bissonnette M Schmitt KM Cotter DR Green TG Cotter 1994 BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death Blood 83 1179 1187
41. K Vancompernolle F Van Herreweghe G Pynaert M Van de Craen K De Vos N Totty A Sterling W Fiers P Vandenabeele J Grooten 1998 Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity FEBS Lett 438 150 158
42. Y Dai M Rahmani SJ Corey P Dent S Grant 2004 A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2 J Biol Chem 279 34227 34239
43. D Cortez G Reuther AM Pendergast 1997 The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells Oncogene 15 2333 2342
44. D Joyce C Albanese J Steer M Fu B Bouzahzah RG Pestell 2001 NF-kappaB and cell-cycle regulation: the cyclin connection Cytokine Growth Factor Rev 12 73 90
45. AB Niculescu 3rd X Chen M Smeets L Hengst C Prives SI Reed 1998 Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication Mol Cell Biol 18 629 643