Plant-derived abrin-a induces apoptosis in cultured leukemic cell lines by different mechanisms

Toxicology and Applied Pharmacology

Volumn 195, Issue 2, 2004, Pages 182-193

  Ohba, Hideki ^a,b   Moriwaki, Sawako ^c   Bakalova, Rumiana ^b   Yasuda, Seiji ^a   Yamasaki, Nobuyuki ^d  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b AIST Shikoku   (Japan)

^c FOOD RESEARCH INSTITUTE   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Abrin a; Acute lymphoblastic leukemia; ALL; Apoptosis; Caspase activity; DNA fragmentation; FITC; Fluorescein isothiocyanate; PBS ( ); Phosphatidylserine translocation

Indexed keywords

ABRIN; CASPASE 3; CASPASE 8; CASPASE 9; PHOSPHATIDYLSERINE;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL MEMBRANE; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOLECULAR DYNAMICS;

ABRIN; ABRUS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 8; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; LEUKEMIA; SEEDS; TIME FACTORS;

EID: 1442348468     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2003.11.018     Document Type: Article

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