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Volumn 24, Issue 2, 2003, Pages 199-207

Thrombospondin 1 - A regulator of adenoma growth and carcinoma progression in the APCMin/+ mouse model

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; SCLEROPROTEIN; THROMBOSPONDIN 1;

EID: 0037328393     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/24.2.199     Document Type: Article
Times cited : (57)

References (55)
  • 1
    • 0025075389 scopus 로고
    • Characterization of the mouse thrombospondin gene and evaluation of the role of the first intron in human gene expression
    • Bornstein,P., Alfi,D., Devarayalu,S., Framson,P. and Li,P. (1990) Characterization of the mouse thrombospondin gene and evaluation of the role of the first intron in human gene expression. J. Biol. Chem., 265, 16691-16698.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16691-16698
    • Bornstein, P.1    Alfi, D.2    Devarayalu, S.3    Framson, P.4    Li, P.5
  • 3
    • 0027199292 scopus 로고
    • Differential expression of thrombospondin 1, 2 and 3 during murine development
    • Iruela-Arispe,M.L., Liska,D.J., Sage,E.H. and Bornstein,P. (1993) Differential expression of thrombospondin 1, 2 and 3 during murine development. Dev. Dyn., 197, 40-56.
    • (1993) Dev. Dyn. , vol.197 , pp. 40-56
    • Iruela-Arispe, M.L.1    Liska, D.J.2    Sage, E.H.3    Bornstein, P.4
  • 4
    • 0028567481 scopus 로고
    • Properties of recombinant mouse thrombospondin 2 expressed in Spodoptera cells
    • Chen,H., Sottile,J., O'Rourke,K.M., Dixit,V.M. and Mosher,D.F. (1994) Properties of recombinant mouse thrombospondin 2 expressed in Spodoptera cells. J. Biol. Chem., 269, 32226-32232.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32226-32232
    • Chen, H.1    Sottile, J.2    O'Rourke, K.M.3    Dixit, V.M.4    Mosher, D.F.5
  • 5
    • 0028577283 scopus 로고
    • Distinct effects of thrombospondin-1 and CISP/thrombospondin-2 on adrenocortical cell spreading
    • Pellerin,S., Lafeuillade,B., Chambaz,E.M. and Feige,J.J. (1994) Distinct effects of thrombospondin-1 and CISP/thrombospondin-2 on adrenocortical cell spreading. Mol. Cell. Endocrinol., 106, 181-186.
    • (1994) Mol. Cell. Endocrinol. , vol.106 , pp. 181-186
    • Pellerin, S.1    Lafeuillade, B.2    Chambaz, E.M.3    Feige, J.J.4
  • 6
    • 0029874628 scopus 로고    scopus 로고
    • Opposite regulation of thrombospondin-1 and corticotropin-induced secreted protein/thrombospondin-2 expression by adrenocorticotropic hormone in adrenocortical cells
    • Lafeuillade,B., Pellerin,S., Keramidas,M., Danik,M., Chambaz,E.M. and Feige,J.J. (1996) Opposite regulation of thrombospondin-1 and corticotropin-induced secreted protein/thrombospondin-2 expression by adrenocorticotropic hormone in adrenocortical cells. J. Cell. Physiol., 167, 164-172.
    • (1996) J. Cell. Physiol. , vol.167 , pp. 164-172
    • Lafeuillade, B.1    Pellerin, S.2    Keramidas, M.3    Danik, M.4    Chambaz, E.M.5    Feige, J.J.6
  • 7
    • 0030736422 scopus 로고    scopus 로고
    • Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system
    • Scott-Drew,S. and French-Constant,C. (1997) Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system. J. Neurosci. Res., 50, 202-214.
    • (1997) J. Neurosci. Res. , vol.50 , pp. 202-214
    • Scott-Drew, S.1    French-Constant, C.2
  • 8
    • 0031773016 scopus 로고    scopus 로고
    • Two-hybrid analysis reveals multiple direct interactions for thrombospondin 1
    • Aho,S. and Uitto,J. (1998) Two-hybrid analysis reveals multiple direct interactions for thrombospondin 1. Matrix Biol., 17, 401-412.
    • (1998) Matrix Biol. , vol.17 , pp. 401-412
    • Aho, S.1    Uitto, J.2
  • 9
    • 0031668289 scopus 로고    scopus 로고
    • The distribution of the matricellular protein thrombospondin 2 in tissues of embryonic and adult mice
    • Kyriakides,T.R., Zhu,Y.H., Yang,Z. and Bornstein,P. (1998) The distribution of the matricellular protein thrombospondin 2 in tissues of embryonic and adult mice. J. Histochem. Cytochem., 46, 1007-1015.
    • (1998) J. Histochem. Cytochem. , vol.46 , pp. 1007-1015
    • Kyriakides, T.R.1    Zhu, Y.H.2    Yang, Z.3    Bornstein, P.4
  • 10
    • 0031833609 scopus 로고    scopus 로고
    • Restricted localization of thrombospondin-2 protein during mouse embryogenesis: A comparison to thrombospondin-1
    • Tooney,P.A., Sakai,J., Sakai,K., Aeschlimann,D. and Mosher,D.F. (1998) Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1. Matrix Biol., 17, 131-143.
    • (1998) Matrix Biol. , vol.17 , pp. 131-143
    • Tooney, P.A.1    Sakai, J.2    Sakai, K.3    Aeschlimann, D.4    Mosher, D.F.5
  • 11
    • 0032707093 scopus 로고    scopus 로고
    • Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene
    • Kyriakides,T.R., Tam,J.W. and Bornstein,P. (1999) Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene. J. Invest. Dermatol., 113, 782-787.
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 782-787
    • Kyriakides, T.R.1    Tam, J.W.2    Bornstein, P.3
  • 12
    • 0343484319 scopus 로고    scopus 로고
    • Central role of thrombospondin-1 in the activation and clonal expansion of cells
    • Vallejo,A.N., Klimiuk,P.A., Weyand,C.M. and Goronzy,J.J. (2000) Central role of thrombospondin-1 in the activation and clonal expansion of cells. J. Immunol., 164, 2947-2954.
    • (2000) J. Immunol. , vol.164 , pp. 2947-2954
    • Vallejo, A.N.1    Klimiuk, P.A.2    Weyand, C.M.3    Goronzy, J.J.4
  • 13
    • 0032926188 scopus 로고    scopus 로고
    • Thrombospondins I and II messenger RNA expression in lung carcinoma: Relationship with p53 alterations, angiogenic growth factors and vascular density
    • Fontanini,G., Boldrini,L., Calcinai,A., Chine,S., Lucchi,M., Mussi,A., Angeletti,C.A., Basolo,F. and Bevilacqua,G. (1999) Thrombospondins I and II messenger RNA expression in lung carcinoma: relationship with p53 alterations, angiogenic growth factors and vascular density. Clin. Cancer Res., 5, 155-161.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 155-161
    • Fontanini, G.1    Boldrini, L.2    Calcinai, A.3    Chine, S.4    Lucchi, M.5    Mussi, A.6    Angeletti, C.A.7    Basolo, F.8    Bevilacqua, G.9
  • 14
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblast by p53 regulation of thrombospondin-1
    • Dameron,K.M., Volpert,O.V., Tainsky,M.A. and Bouck,N. (1994) Control of angiogenesis in fibroblast by p53 regulation of thrombospondin-1. Science, 265, 1582-1584.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 15
    • 0031080174 scopus 로고    scopus 로고
    • Endothelial cell mitogenesis induced by LPA: Inhibition by thrombospondin-1 and thrombospondin-2
    • Panetti,T.S., Chen,H., Misenheimer,T.M., Getzler,S.B. and Mosher,D.F. (1997) Endothelial cell mitogenesis induced by LPA: inhibition by thrombospondin-1 and thrombospondin-2. J. Lab. Clin. Med., 129, 208-216.
    • (1997) J. Lab. Clin. Med. , vol.129 , pp. 208-216
    • Panetti, T.S.1    Chen, H.2    Misenheimer, T.M.3    Getzler, S.B.4    Mosher, D.F.5
  • 21
    • 0031193866 scopus 로고    scopus 로고
    • Lumen formation and other angiogenic activities of cultured capillary endothelial cells are inhibited by thrombospondin-1
    • Tolsma,S., Stack,M.S. and Bouck,N. (1997) Lumen formation and other angiogenic activities of cultured capillary endothelial cells are inhibited by thrombospondin-1. Microvascular Res., 54, 13-26.
    • (1997) Microvascular Res. , vol.54 , pp. 13-26
    • Tolsma, S.1    Stack, M.S.2    Bouck, N.3
  • 22
    • 14444283886 scopus 로고    scopus 로고
    • Thrombospondin 2 gene expression is correlated with decreased vascularity in non-small cell lung cancer
    • Oshika,Y., Masuda,K., Tokunaga,T. et al. (1998) Thrombospondin 2 gene expression is correlated with decreased vascularity in non-small cell lung cancer. Clin. Cancer Res., 4, 1785-1788.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1785-1788
    • Oshika, Y.1    Masuda, K.2    Tokunaga, T.3
  • 23
    • 0033551072 scopus 로고    scopus 로고
    • Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity
    • Kyriakides,T.R., Leach,K.J., Hoffman,A.S., Ratner,B.D. and Bornstein,P. (1999) Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity. Proc. Natl Acad. Sci. USA, 96, 4449-4454.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4449-4454
    • Kyriakides, T.R.1    Leach, K.J.2    Hoffman, A.S.3    Ratner, B.D.4    Bornstein, P.5
  • 24
    • 0032770860 scopus 로고    scopus 로고
    • Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas
    • Streit,M., Velasco,P., Brown,L.F., Skobe,M., Richard,L., Riccardi,L., Lawler,J. and Detmar,M. (1999) Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas. Am. J. Pathol., 155, 441-452.
    • (1999) Am. J. Pathol. , vol.155 , pp. 441-452
    • Streit, M.1    Velasco, P.2    Brown, L.F.3    Skobe, M.4    Richard, L.5    Riccardi, L.6    Lawler, J.7    Detmar, M.8
  • 26
    • 0032894743 scopus 로고    scopus 로고
    • Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer
    • Tokunaga,T., Nakamura,M., Oshika,Y. et al. (1999) Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer. Br. J. Cancer, 79, 354-359.
    • (1999) Br. J. Cancer , vol.79 , pp. 354-359
    • Tokunaga, T.1    Nakamura, M.2    Oshika, Y.3
  • 28
    • 0032622417 scopus 로고    scopus 로고
    • Expression of the thrombospondin 1 receptor CD36 is correlated with decreased stromal vascularisation in colon cancer
    • Tsuchida,T., Kijima,H., Tokunaga,T. et al. (1999) Expression of the thrombospondin 1 receptor CD36 is correlated with decreased stromal vascularisation in colon cancer. Int. J. Oncol., 14, 47-51.
    • (1999) Int. J. Oncol. , vol.14 , pp. 47-51
    • Tsuchida, T.1    Kijima, H.2    Tokunaga, T.3
  • 29
    • 14444282619 scopus 로고    scopus 로고
    • Alterations in tumour suppressor gene p53 correlate with inhibition of thrombospondin-1 expression in colon cancer cells
    • Tokunaga,T., Nakamura,M., Oshika,Y. et al. (1998) Alterations in tumour suppressor gene p53 correlate with inhibition of thrombospondin-1 expression in colon cancer cells. Virchows Arch., 433, 415-418.
    • (1998) Virchows Arch. , vol.433 , pp. 415-418
    • Tokunaga, T.1    Nakamura, M.2    Oshika, Y.3
  • 30
    • 0031057680 scopus 로고    scopus 로고
    • Thrombospondin-1 and -2 messenger RNA expression in normal, benign and neoplastic human breast tissues: Correlation with prognostic factors, tumor angiogenesis and fibroblastic desmoplasia
    • Bertin,N., Clezardin,P., Kubiak,R. and Frappart,L. (1997) Thrombospondin-1 and -2 messenger RNA expression in normal, benign and neoplastic human breast tissues: correlation with prognostic factors, tumor angiogenesis and fibroblastic desmoplasia. Cancer Res., 57, 396-399.
    • (1997) Cancer Res. , vol.57 , pp. 396-399
    • Bertin, N.1    Clezardin, P.2    Kubiak, R.3    Frappart, L.4
  • 31
  • 32
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser,A.R., Pitot,H.C. and Dove,W.F. (1990) A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science, 247, 322-324.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 33
    • 0032030891 scopus 로고    scopus 로고
    • Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia
    • Lawler,J., Sunday,M., Thibert,V., Duquette,M., George,E.L., Rayburn,H. and Hynes,R.O. (1998) Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. J. Clin. Invest., 101, 982-992.
    • (1998) J. Clin. Invest. , vol.101 , pp. 982-992
    • Lawler, J.1    Sunday, M.2    Thibert, V.3    Duquette, M.4    George, E.L.5    Rayburn, H.6    Hynes, R.O.7
  • 34
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ specific labeling of nuclear DNA fragmentation
    • Gavrieli,Y., Sherman,Y. and Ben-Sasson,S. (1992) Identification of programmed cell death in situ specific labeling of nuclear DNA fragmentation. J. Cell. Biol., 119, 493-501.
    • (1992) J. Cell. Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.3
  • 35
    • 19244385544 scopus 로고    scopus 로고
    • Stromal thrombospondin-1 expression is correlated with progression of esophageal squamous cell carcinomas
    • Oshiba,G., Kijima,H., Himeno,S. et al. (1999) Stromal thrombospondin-1 expression is correlated with progression of esophageal squamous cell carcinomas. Anticancer Res., 19, 4375-4378.
    • (1999) Anticancer Res. , vol.19 , pp. 4375-4378
    • Oshiba, G.1    Kijima, H.2    Himeno, S.3
  • 36
    • 0033010512 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is up regulated in the early pre-malignant stage of colorectal tumor progression
    • Wong,M., Cheung,N., Yuen,S.T., Leung,S.Y. and Vhung,L.P. (1999) Vascular endothelial growth factor is up regulated in the early pre-malignant stage of colorectal tumor progression. Int. J. Cancer, 81, 845-850.
    • (1999) Int. J. Cancer , vol.81 , pp. 845-850
    • Wong, M.1    Cheung, N.2    Yuen, S.T.3    Leung, S.Y.4    Vhung, L.P.5
  • 38
    • 0035149332 scopus 로고    scopus 로고
    • Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice
    • Lawler,J., Miao,W.M., Duquette,M., Bouck,N., Bronson,R.T. and Hynes,R.O. (2001) Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. Am. J. Path., 159, 1949-1956.
    • (2001) Am. J. Path. , vol.159 , pp. 1949-1956
    • Lawler, J.1    Miao, W.M.2    Duquette, M.3    Bouck, N.4    Bronson, R.T.5    Hynes, R.O.6
  • 39
  • 40
    • 0027077495 scopus 로고
    • Transforming growth factor-beta complexes with thrombospondin
    • Murphy-Ullrich,J.E., Schultz-Cherry,S. and Hook,M. (1992) Transforming growth factor-beta complexes with thrombospondin. Mol. Biol. Cell., 3, 181-188.
    • (1992) Mol. Biol. Cell. , vol.3 , pp. 181-188
    • Murphy-Ullrich, J.E.1    Schultz-Cherry, S.2    Hook, M.3
  • 41
    • 0027305971 scopus 로고
    • Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism
    • Schultz-Cherry,S. and Murphy-Ullrich,J.E. (1993) Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism. J. Cell. Biol., 122, 923-932.
    • (1993) J. Cell. Biol. , vol.122 , pp. 923-932
    • Schultz-Cherry, S.1    Murphy-Ullrich, J.E.2
  • 42
    • 0027503601 scopus 로고
    • Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta)
    • Roberts,A.B and Sporn,M.B. (1993) Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta). Growth Fact., 8, 1-9.
    • (1993) Growth Fact. , vol.8 , pp. 1-9
    • Roberts, A.B.1    Sporn, M.B.2
  • 44
    • 0030953159 scopus 로고    scopus 로고
    • Decreased transforming growth factor beta type II receptor expression in intestinal adenomas from Min/+ mice is associated with increased cyclin D1 and cyclin-dependent kinase 4 expression
    • Zhang,T., Nanney,L.B., Peeler,M.O., Williams,C.S., Lamps,L., Heppner,K.J., DuBois,R.N. and Beauchamp,R.D. (1997) Decreased transforming growth factor beta type II receptor expression in intestinal adenomas from Min/+ mice is associated with increased cyclin D1 and cyclin-dependent kinase 4 expression. Cancer Res., 57, 1638-1643.
    • (1997) Cancer Res. , vol.57 , pp. 1638-1643
    • Zhang, T.1    Nanney, L.B.2    Peeler, M.O.3    Williams, C.S.4    Lamps, L.5    Heppner, K.J.6    DuBois, R.N.7    Beauchamp, R.D.8
  • 46
    • 0034572042 scopus 로고    scopus 로고
    • Beta-catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma
    • Brabletz,T., Jung,A., Dag,S., Reu,S. and Kirchner,T. (2000) Beta-catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma. Verh. Dtsch. Ges. Pathol., 84, 175-181.
    • (2000) Verh. Dtsch. Ges. Pathol. , vol.84 , pp. 175-181
    • Brabletz, T.1    Jung, A.2    Dag, S.3    Reu, S.4    Kirchner, T.5
  • 47
    • 0028936280 scopus 로고
    • Thrombospondin modulates human breast adenocarcinoma cell adhesion to human vascular endothelial cells
    • Incardona,F., Lewalle,J.M., Morandi,V., Lambert,S., Legrand,Y., Foidart,J.M. and Legrand,C. (1995) Thrombospondin modulates human breast adenocarcinoma cell adhesion to human vascular endothelial cells. Cancer Res., 55, 166-173.
    • (1995) Cancer Res. , vol.55 , pp. 166-173
    • Incardona, F.1    Lewalle, J.M.2    Morandi, V.3    Lambert, S.4    Legrand, Y.5    Foidart, J.M.6    Legrand, C.7
  • 48
    • 0032896852 scopus 로고    scopus 로고
    • Thrombospondin-1 induces tyrosine phosphorylation of adherens junction proteins and regulates an endothelial paracellular pathway
    • Goldblum,S.E., Young,B.A., Wang,P. and Murphy-Ullrich,J.E. (1999) Thrombospondin-1 induces tyrosine phosphorylation of adherens junction proteins and regulates an endothelial paracellular pathway. Mol. Biol. Cell., 10, 1537-1551.
    • (1999) Mol. Biol. Cell. , vol.10 , pp. 1537-1551
    • Goldblum, S.E.1    Young, B.A.2    Wang, P.3    Murphy-Ullrich, J.E.4
  • 49
    • 0029091325 scopus 로고
    • Thrombospondin and transforming growth factor-beta 1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells
    • Arnoletti,J.P., Albo,D., Granick,M.S., Solomon,M.P., Castiglioni,A., Rothman,V.L. and Tuszynski,G.P. (1995) Thrombospondin and transforming growth factor-beta 1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cells. Cancer, 76, 998-1005.
    • (1995) Cancer , vol.76 , pp. 998-1005
    • Arnoletti, J.P.1    Albo, D.2    Granick, M.S.3    Solomon, M.P.4    Castiglioni, A.5    Rothman, V.L.6    Tuszynski, G.P.7
  • 50
    • 0034667385 scopus 로고    scopus 로고
    • Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
    • Gutierrez,L.S., Schulman,A., Brito-Robinson,T., Noria,F., Ploplis,V.A. and Castellino,F.J. (2000) Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Res., 60, 5839-5847.
    • (2000) Cancer Res. , vol.60 , pp. 5839-5847
    • Gutierrez, L.S.1    Schulman, A.2    Brito-Robinson, T.3    Noria, F.4    Ploplis, V.A.5    Castellino, F.J.6
  • 51
    • 0031979317 scopus 로고    scopus 로고
    • Mutant p53 correlates with reduced expression of thrombospondin-1, increased angiogenesis and metastatic progression in melanoma
    • Grant,S.W., Kyshtoobayeva,A.S., Kurosaki,T., Jakowatz,J. and Fruehauf,J.P. (1998) Mutant p53 correlates with reduced expression of thrombospondin-1, increased angiogenesis and metastatic progression in melanoma. Cancer Detect. Prev., 22, 185-194.
    • (1998) Cancer Detect. Prev. , vol.22 , pp. 185-194
    • Grant, S.W.1    Kyshtoobayeva, A.S.2    Kurosaki, T.3    Jakowatz, J.4    Fruehauf, J.P.5
  • 52
    • 0034902029 scopus 로고    scopus 로고
    • Thrombospondin-1 expression in epithelial ovarian carcinoma: Association with p53 status, tumor angiogenesis and survival in platinum-treated patients
    • Alvarez,A.A., Axelrod,J.R., Whitaker,R.S., Isner,P.D., Bentley,R.C., Dodge,R.K. and Rodriguez,G.C. (2001) Thrombospondin-1 expression in epithelial ovarian carcinoma: association with p53 status, tumor angiogenesis and survival in platinum-treated patients. Gynecol. Oncol., 82, 273-278.
    • (2001) Gynecol. Oncol. , vol.82 , pp. 273-278
    • Alvarez, A.A.1    Axelrod, J.R.2    Whitaker, R.S.3    Isner, P.D.4    Bentley, R.C.5    Dodge, R.K.6    Rodriguez, G.C.7
  • 54
    • 0035403794 scopus 로고    scopus 로고
    • Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer
    • Maeda,K., Nishiguchi,Y., Kang,S.M., Yashiro,M., Onoda,N., Sawada,T., Ishikawa,T. and Hirakawa,K. (2001) Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer. Oncol. Rep., 8, 763-766.
    • (2001) Oncol. Rep. , vol.8 , pp. 763-766
    • Maeda, K.1    Nishiguchi, Y.2    Kang, S.M.3    Yashiro, M.4    Onoda, N.5    Sawada, T.6    Ishikawa, T.7    Hirakawa, K.8
  • 55
    • 0035940429 scopus 로고    scopus 로고
    • Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
    • Rodriguez-Manzaneque,J.C., Lane,T.F., Ortega,M.A., Hynes,R.O., Lawler,J. and Iruela-Arispe,M.L. (2001) Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc. Natl Acad. Sci. USA, 98, 12485-23490.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12485-23490
    • Rodriguez-Manzaneque, J.C.1    Lane, T.F.2    Ortega, M.A.3    Hynes, R.O.4    Lawler, J.5    Iruela-Arispe, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.