Thromboxane-B2 levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 63, Issue 4, 2000, Pages 217-221

  Thomson, M ^a   Mustafa, T ^b   Ali, M ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GARLIC EXTRACT; ONION EXTRACT; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; THROMBOXANE B2;

ANIMAL EXPERIMENT; ANTICOAGULATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROSTAGLANDIN SYNTHESIS; RABBIT; THROMBOCYTE AGGREGATION INHIBITION; THROMBOSIS PREVENTION;

ALLIUM CEPA; ALLIUM SATIVUM; ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0033758559     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.2000.0212     Document Type: Article

References (27)

1. Antiplatelet treatment for thromboprophylaxis - A step forward or backwards. Antiplatelet Trialists' Collaboration
2. Antiplatelet therapy in the treatment and prevention of vascular disease: Some clear answers, some new questio'ns
3. Platelets and thrombolytic therapy
4. Swedish Aspirin Low-dose Trial (SALT) of 75 mg aspirin as secondary prophylaxis after cerebrovascular ischemic events
5. Aceylation of human prostaglandin endoperoxide synthase-2 by aspirin
6. Aqueous extracts of onion, garlic, and ginger inhibits platelet aggregation and alters arachidonic acid metabolism
7. Selective suppression of platelet thromboxane formation with sparing of vascular prostacyclin synthesis by aqueous extract of garlic in rabbits
8. Inhibition of whole blood platelet aggregation by compounds in garlic clove extracts and commercial garlic products
9. Effect of raw versus boiled aqueous extract of garlic and onion on platelet aggregation
10. Isolation and effects of some garlic components on platelet aggregation and metabolism of arachidonic acid in human blood platelets
11. Mechanism by which garlic (Allium sativum) inhibits cyclooxygenase activity. Effect of raw versus boiled garlic extract on the synthesis of prostanoids
12. The effect of fried versus raw garlic on fibrinolytic activity in man
13. 2 during infusion of arachidonic acid and collagen in rabbits
14. An evaluation of garlic and onion as antithrombotic agents
15. 2 production in rats
16. 2 and 6-keto PGF(1-α) by bovine gastric mucosal and muscle microsomes
17. Impaired platelet/connective tissue reaction after aspirin ingestion
18. Focused antithrombotic therapy: Novel antiplatelet salicylates with reduced ulcerogenic potential and higher first-pass detoxification than aspirin in rats
19. Consumption of a garlic clove a day could be beneficial in preventing thrombosis
20. Plasma acetylsalicylate and sahcylate and platelet cyclooxygenase activity following plain and enteric coated aspirin
21. Possible significance of small numbers of functional platelets in a population of aspirin-treated platelets in vitro and in vivo
22. Reversible, and irreversible inhibition of platelet cyclooxygenase and serotonin release by non-steroidal anti-inflammatory drugs
23. Evidence for the mechanism by which garlic inhibits platelet aggregation
24. Effects of single oral dose of lysine clonixinate and acetylsalicylic acid on platelet functions in man
25. Small dose aspirin treatment on vascular diseases
26. Pharmacokinetics of vinyldithiins, transformation products of allicin
27. Effect of onion and ginger consumption on platelet thromboxane production in humans