A novel approach to determining physicochemical and absorption properties of 6-fluoroquinolone derivatives: Experimental assessment

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 53, Issue 3, 2002, Pages 317-325

  Cabrera Pérez, Miguel Angel ^a   González Díaz, Humberto ^a   Fernández Teruel, Carlos ^b   Plá Delfina, José Ma ^b   Bermejo Sanz, Marival ^b  

^a CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

6 Fluoroquinolone; Absorption; Physicochemical property; Sarafloxacin; Sparfloxacin; Structure property relationship; ToSS MoDe approach

Indexed keywords

CIPROFLOXACIN; CIPROFLOXACIN DERIVATIVE; CNV 8706; CNV 8804; CNV 8919; CNV 9201; CNV 97100; ENOXACIN; ENROFLOXACIN; FLEROXACIN; FLUMEQUINE; GREPAFLOXACIN; LOMEFLOXACIN; NORDIFLOXACIN; NORFLOXACIN; NORFLOXACIN DERIVATIVE; OFLOXACIN; PEFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TEMAFLOXACIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FACTORIAL ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; LIPOPHILICITY; MALE; NONHUMAN; PARTITION COEFFICIENT; RAT; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

ANIMALS; ANTI-INFECTIVE AGENTS; FLUOROQUINOLONES; INTESTINAL ABSORPTION; MALE; MODELS, BIOLOGICAL; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036218627     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(02)00013-9     Document Type: Article

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