Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine

Molecular Pain

Volumn 5, Issue , 2009, Pages

  Garzón, Javier ^a,b   de la Torre Madrid, Elena ^a,b   Rodríguez Muñoz, María ^b   Vicente Sánchez, Ana ^a,b   Sánchez Blázquez, Pilar ^a,b  

^a INSTITUTO CAJAL   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; BRAIN RECEPTOR; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR AGONIST; GUANINE NUCLEOTIDE BINDING PROTEIN; METHANANDAMIDE; MORPHINE; MU OPIATE RECEPTOR; PERTUSSIS TOXIN; PROTEIN GZ; UNCLASSIFIED DRUG; CANNABINOID; GNAZ PROTEIN, MOUSE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG CROSS TOLERANCE; DRUG RECEPTOR BINDING; MALE; MORPHINE TOLERANCE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPINAL ANESTHESIA; ANALGESIA; ANIMAL; BRAIN LEVEL; DRUG EFFECT; DRUG POTENTIATION; DRUG TOLERANCE; MOUSE STRAIN; PHYSIOLOGY;

ANALGESIA; ANIMALS; BRAIN CHEMISTRY; CANNABINOIDS; DRUG TOLERANCE; GTP-BINDING PROTEIN ALPHA SUBUNITS; MALE; MICE; MICE, INBRED STRAINS; MORPHINE; RECEPTOR, CANNABINOID, CB1; RECEPTORS, OPIOID, MU;

EID: 63049114542     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-5-11     Document Type: Article

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