메뉴 건너뛰기




Volumn 8, Issue 3, 2009, Pages 433-442

High content cell screening in a microfluidic device

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOTRANSFERASE; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR;

EID: 63049111520     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.M800291-MCP200     Document Type: Article
Times cited : (59)

References (52)
  • 1
    • 28844441230 scopus 로고    scopus 로고
    • A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
    • Janes, K A., Albeck, J. G., Gaudet, S., Sorger, P. K., Lauffenburger, D. A., and Yaffe, M. B. (2005) A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis, Science 310, 1646-1653
    • (2005) Science , vol.310 , pp. 1646-1653
    • Janes, K.A.1    Albeck, J.G.2    Gaudet, S.3    Sorger, P.K.4    Lauffenburger, D.A.5    Yaffe, M.B.6
  • 2
    • 33646036758 scopus 로고    scopus 로고
    • The response of human epithelial cells to TNF involves an inducible autocrine cascade
    • Janes, K. A., Gaudet, S., Albeck, J. G., Nielsen, U. B., Lauffenburger, D. A., and Sorger, P. K. (2006) The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell 124, 1225-1239
    • (2006) Cell , vol.124 , pp. 1225-1239
    • Janes, K.A.1    Gaudet, S.2    Albeck, J.G.3    Nielsen, U.B.4    Lauffenburger, D.A.5    Sorger, P.K.6
  • 3
  • 4
    • 17644427718 scopus 로고    scopus 로고
    • Causal protein-signaling networks derived from multiparameter single-cell data
    • Sachs, K., Perez, O., Pe'er, D., Lauffenburger, D. A., and Nolan, G. P. (2005) Causal protein-signaling networks derived from multiparameter single-cell data. Science 308, 523-529
    • (2005) Science , vol.308 , pp. 523-529
    • Sachs, K.1    Perez, O.2    Pe'er, D.3    Lauffenburger, D.A.4    Nolan, G.P.5
  • 5
    • 0034009901 scopus 로고    scopus 로고
    • An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells
    • Cluzel, P., Surette, M., and Leibler, S. (2000) An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science 287, 1652-1655
    • (2000) Science , vol.287 , pp. 1652-1655
    • Cluzel, P.1    Surette, M.2    Leibler, S.3
  • 6
    • 0037040545 scopus 로고    scopus 로고
    • Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module
    • Teruel, M. N., and Meyer, T. (2002) Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module. Science 295, 1910-1912
    • (2002) Science , vol.295 , pp. 1910-1912
    • Teruel, M.N.1    Meyer, T.2
  • 7
    • 0032496358 scopus 로고    scopus 로고
    • The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes
    • Ferrell, J. E., Jr., and Machleder, E. M. (1998) The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes. Science 280, 895-898
    • (1998) Science , vol.280 , pp. 895-898
    • Ferrell Jr., J.E.1    Machleder, E.M.2
  • 8
    • 33846097600 scopus 로고    scopus 로고
    • Dynamics of single-cell gene expression
    • Longo, D., and Hasty, J. (2006) Dynamics of single-cell gene expression. Mol. Syst. Biol. 2, 64
    • (2006) Mol. Syst. Biol , vol.2 , pp. 64
    • Longo, D.1    Hasty, J.2
  • 11
    • 0033946897 scopus 로고    scopus 로고
    • Limitations on the use of fused green fluorescent protein to investigate structure-function relationships for the cauliflower mosaic virus movement protein
    • Thomas, C. L., and Maule, A. J. (2000) Limitations on the use of fused green fluorescent protein to investigate structure-function relationships for the cauliflower mosaic virus movement protein. J. Gen. Virol. 81, 1851-1855
    • (2000) J. Gen. Virol , vol.81 , pp. 1851-1855
    • Thomas, C.L.1    Maule, A.J.2
  • 12
    • 15944426727 scopus 로고    scopus 로고
    • Comment on Oscillations in NF-κB signaling control the dynamics of gene expression
    • Barken, D., Wang, C. J., Kearns, J., Cheong, R., Hoffmann, A., and Levchenko, A. (2005) Comment on "Oscillations in NF-κB signaling control the dynamics of gene expression." Science 308, 52
    • (2005) Science , vol.308 , pp. 52
    • Barken, D.1    Wang, C.J.2    Kearns, J.3    Cheong, R.4    Hoffmann, A.5    Levchenko, A.6
  • 14
    • 33947195310 scopus 로고    scopus 로고
    • Bridging the gap between in silico and cell-based analysis of the nuclear factor-κB signaling pathway by in vitro studies of IKK2
    • Ihekwaba, A. E., Wilkinson, S. J., Waithe, D., Broomhead, D. S., Li, P., Grimley, R. L., and Benson, N. (2007) Bridging the gap between in silico and cell-based analysis of the nuclear factor-κB signaling pathway by in vitro studies of IKK2. FEBS J. 274, 1678-1690
    • (2007) FEBS J , vol.274 , pp. 1678-1690
    • Ihekwaba, A.E.1    Wilkinson, S.J.2    Waithe, D.3    Broomhead, D.S.4    Li, P.5    Grimley, R.L.6    Benson, N.7
  • 16
    • 38349043669 scopus 로고    scopus 로고
    • High-content single-cell drug screening with phosphospecific flow cytometry
    • Krutzik, P. O., Crane, J. M., Clutter, M. R., and Nolan, G. P. (2008) High-content single-cell drug screening with phosphospecific flow cytometry. Nat. Chem. Biol. 4, 132-142
    • (2008) Nat. Chem. Biol , vol.4 , pp. 132-142
    • Krutzik, P.O.1    Crane, J.M.2    Clutter, M.R.3    Nolan, G.P.4
  • 18
    • 1642463417 scopus 로고    scopus 로고
    • Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications
    • Krutzik, P. O., Irish, J. M., Nolan, G. P., and Perez, O. D. (2004) Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Clin. Immunol. 110, 206-221
    • (2004) Clin. Immunol , vol.110 , pp. 206-221
    • Krutzik, P.O.1    Irish, J.M.2    Nolan, G.P.3    Perez, O.D.4
  • 22
    • 21844440569 scopus 로고    scopus 로고
    • Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
    • Pelkmans, L., Fava, E., Grabner, H., Hannus, M., Habermann, B., Krausz, E., and Zerial, M. (2005) Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature 436, 78-86
    • (2005) Nature , vol.436 , pp. 78-86
    • Pelkmans, L.1    Fava, E.2    Grabner, H.3    Hannus, M.4    Habermann, B.5    Krausz, E.6    Zerial, M.7
  • 23
    • 0034582001 scopus 로고    scopus 로고
    • Dunn, D. A., and Feygin, 1. (2000) Challenges and solutions to ultra-high-throughput screening assay miniaturization: submicroliter fluid handling. Drug Discov. Today 5, 84-91
    • Dunn, D. A., and Feygin, 1. (2000) Challenges and solutions to ultra-high-throughput screening assay miniaturization: submicroliter fluid handling. Drug Discov. Today 5, 84-91
  • 24
    • 33947395259 scopus 로고    scopus 로고
    • High-content siRNA screening
    • Krausz, E. (2007) High-content siRNA screening. Mol. Biosyst. 3, 232-240
    • (2007) Mol. Biosyst , vol.3 , pp. 232-240
    • Krausz, E.1
  • 25
    • 33750810263 scopus 로고    scopus 로고
    • High-content screening: Emerging hardware and software technologies
    • Lee, S., and Howell, B. J. (2006) High-content screening: emerging hardware and software technologies. Methods Enzymol. 414, 468-483
    • (2006) Methods Enzymol , vol.414 , pp. 468-483
    • Lee, S.1    Howell, B.J.2
  • 26
    • 33847411140 scopus 로고    scopus 로고
    • High-throughput microfluidics: Improved sample treatment and washing over standard wells
    • Warrick, J., Meyvantsson, I., Ju, J., and Beebe, D. J. (2007) High-throughput microfluidics: improved sample treatment and washing over standard wells. Lab Chip 7, 316-321
    • (2007) Lab Chip , vol.7 , pp. 316-321
    • Warrick, J.1    Meyvantsson, I.2    Ju, J.3    Beebe, D.J.4
  • 27
    • 33746306815 scopus 로고    scopus 로고
    • Enhanced signals and fast nucleic acid hybridization by microfluidic chaotic mixing
    • Liu, J., Williams, B. A., Gwirtz, R. M., Wold, B. J., and Quake, S. (2006) Enhanced signals and fast nucleic acid hybridization by microfluidic chaotic mixing. Angew. Chem. Int. Ed. Engl. 45, 3618-3623
    • (2006) Angew. Chem. Int. Ed. Engl , vol.45 , pp. 3618-3623
    • Liu, J.1    Williams, B.A.2    Gwirtz, R.M.3    Wold, B.J.4    Quake, S.5
  • 29
    • 0036022527 scopus 로고    scopus 로고
    • Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device
    • Li Jeon, N., Baskaran, H., Dertinger, S. K., Whitesides, G. M., Van de Water, L., and Toner, M. (2002) Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat. Biotechnol. 20, 826-830
    • (2002) Nat. Biotechnol , vol.20 , pp. 826-830
    • Li Jeon, N.1    Baskaran, H.2    Dertinger, S.K.3    Whitesides, G.M.4    Van de Water, L.5    Toner, M.6
  • 30
    • 33745686447 scopus 로고    scopus 로고
    • Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes
    • Kane, B. J., Zinner, M. J., Yarmush, M. L., and Toner, M. (2006) Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes. Anal. Chem. 78, 4291-4298
    • (2006) Anal. Chem , vol.78 , pp. 4291-4298
    • Kane, B.J.1    Zinner, M.J.2    Yarmush, M.L.3    Toner, M.4
  • 31
    • 12344282703 scopus 로고    scopus 로고
    • Differentiation-on-a-chip: A microfluidic platform for long-term cell culture studies
    • Tourovskaia, A., Figueroa-Masot, X., and Folch, A. (2005) Differentiation-on-a-chip: a microfluidic platform for long-term cell culture studies. Lab Chip 5, 14-19
    • (2005) Lab Chip , vol.5 , pp. 14-19
    • Tourovskaia, A.1    Figueroa-Masot, X.2    Folch, A.3
  • 32
    • 33847391281 scopus 로고    scopus 로고
    • A plate reader-compatible microchannel array for cell biology assays
    • Yu, H., Alexander, C. M., and Beebe, D. J. (2007) A plate reader-compatible microchannel array for cell biology assays. Lab Chip 7, 388-391
    • (2007) Lab Chip , vol.7 , pp. 388-391
    • Yu, H.1    Alexander, C.M.2    Beebe, D.J.3
  • 33
    • 33845761551 scopus 로고    scopus 로고
    • A high-throughput microfluidic real-time gene expression living cell array
    • King, K. R., Wang, S., Irimia, D., Jayaraman, A., Toner, M., and Yarmush, M. L. (2007) A high-throughput microfluidic real-time gene expression living cell array. Lab Chip 7, 77-85
    • (2007) Lab Chip , vol.7 , pp. 77-85
    • King, K.R.1    Wang, S.2    Irimia, D.3    Jayaraman, A.4    Toner, M.5    Yarmush, M.L.6
  • 35
    • 33947686032 scopus 로고    scopus 로고
    • Analysis of single mammalian cells on-chip
    • Sims, C. E., and Allbritton, N. L. (2007) Analysis of single mammalian cells on-chip. Lab Chip 7, 423-440
    • (2007) Lab Chip , vol.7 , pp. 423-440
    • Sims, C.E.1    Allbritton, N.L.2
  • 36
    • 0023642534 scopus 로고
    • The use of a charge-coupled device for quantitative optical microscopy of biological structures
    • Hiraoka, Y., Sedat, J. W., and Agard, D. A. (1987) The use of a charge-coupled device for quantitative optical microscopy of biological structures. Science 238, 36-41
    • (1987) Science , vol.238 , pp. 36-41
    • Hiraoka, Y.1    Sedat, J.W.2    Agard, D.A.3
  • 37
    • 0034615958 scopus 로고    scopus 로고
    • Monolithic microfabricated valves and pumps by multilayer soft lithography
    • Unger, M. A., Chou, H. P., Thorsen, T., Scherer, A., and Quake, S. R. (2000) Monolithic microfabricated valves and pumps by multilayer soft lithography. Science 288, 113-116
    • (2000) Science , vol.288 , pp. 113-116
    • Unger, M.A.1    Chou, H.P.2    Thorsen, T.3    Scherer, A.4    Quake, S.R.5
  • 38
    • 0037131390 scopus 로고    scopus 로고
    • Microfluldic large-scale integration
    • Thorsen, T., Maerkl, S. J., and Quake, S. R. (2002) Microfluldic large-scale integration. Science 298, 580-584
    • (2002) Science , vol.298 , pp. 580-584
    • Thorsen, T.1    Maerkl, S.J.2    Quake, S.R.3
  • 39
    • 33645303243 scopus 로고    scopus 로고
    • The distribution of freely suspended particles at microfluidic bifurcations
    • Roberts, B. W., and Olbricht, W. L. (2006) The distribution of freely suspended particles at microfluidic bifurcations. AlChE J. 52, 199-206
    • (2006) AlChE J , vol.52 , pp. 199-206
    • Roberts, B.W.1    Olbricht, W.L.2
  • 40
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden, M. S., and Ghosh, S. (2004) Signaling to NF-κB. Genes Dev. 18, 2195-2224
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 41
    • 33646382406 scopus 로고    scopus 로고
    • Transient IκB kinase activity mediates temporal NF-κB dynamics in response to a wide range of tumor necrosis factor-α doses
    • Cheong, R., Bergmann, A., Werner, S. L., Regal, J., Hoffmann, A., and Levchenko, A. (2006) Transient IκB kinase activity mediates temporal NF-κB dynamics in response to a wide range of tumor necrosis factor-α doses. J. Biol. Chem. 281, 2945-2950
    • (2006) J. Biol. Chem , vol.281 , pp. 2945-2950
    • Cheong, R.1    Bergmann, A.2    Werner, S.L.3    Regal, J.4    Hoffmann, A.5    Levchenko, A.6
  • 42
    • 0037044575 scopus 로고    scopus 로고
    • The IκB-NF-κB signaling module: Temporal control and selective gene activation
    • Hoffmann, A., Levchenko, A., Scott, M. L., and Baltimore, D. (2002) The IκB-NF-κB signaling module: temporal control and selective gene activation. Science 298, 1241-1245
    • (2002) Science , vol.298 , pp. 1241-1245
    • Hoffmann, A.1    Levchenko, A.2    Scott, M.L.3    Baltimore, D.4
  • 43
    • 14844358192 scopus 로고    scopus 로고
    • Ultrasensitivity and noise propagation in a synthetic transcriptional cascade
    • Hooshangi, S., Thiberge, S., and Weiss, R. (2005) Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. Proc. Natl. Acad. Sci. U. S. A. 102, 3581-3586
    • (2005) Proc. Natl. Acad. Sci. U. S. A , vol.102 , pp. 3581-3586
    • Hooshangi, S.1    Thiberge, S.2    Weiss, R.3
  • 44
    • 15544388848 scopus 로고    scopus 로고
    • Noise propagation in gene networks
    • Pedraza, J. M., and van Oudenaarden, A. (2005) Noise propagation in gene networks. Science 307, 1965-1969
    • (2005) Science , vol.307 , pp. 1965-1969
    • Pedraza, J.M.1    van Oudenaarden, A.2
  • 45
    • 0036051342 scopus 로고    scopus 로고
    • Molecular interpretation of ERK signal duration by immediate early gene products
    • Murphy, L. O., Smith, S., Chen, R. H., Fingar, D. C., and Blenis, J. (2002) Molecular interpretation of ERK signal duration by immediate early gene products. Nat. Cell Biol. 4, 556-564
    • (2002) Nat. Cell Biol , vol.4 , pp. 556-564
    • Murphy, L.O.1    Smith, S.2    Chen, R.H.3    Fingar, D.C.4    Blenis, J.5
  • 48
    • 0033712615 scopus 로고    scopus 로고
    • Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
    • Zhang, S. Q., Kovalenko, A., Cantarella, G., and Wallach, D. (2000) Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation. Immunity 12, 301-311
    • (2000) Immunity , vol.12 , pp. 301-311
    • Zhang, S.Q.1    Kovalenko, A.2    Cantarella, G.3    Wallach, D.4
  • 49
    • 0028351535 scopus 로고
    • TNF induces internalization of the p60 receptor and shedding of the p80 receptor
    • Higuchi, M., and Aggarwal, B. B. (1994) TNF induces internalization of the p60 receptor and shedding of the p80 receptor. J. Immunol. 152, 3550-3558
    • (1994) J. Immunol , vol.152 , pp. 3550-3558
    • Higuchi, M.1    Aggarwal, B.B.2
  • 51
    • 0036173143 scopus 로고    scopus 로고
    • Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry
    • Perez, O. D., and Nolan, G. P. (2002) Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Nat. Biotechnol. 20, 155-162
    • (2002) Nat. Biotechnol , vol.20 , pp. 155-162
    • Perez, O.D.1    Nolan, G.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.