An unbiased cell morphology-based screen for new, biologically active small molecules

PLoS Biology

Volumn 3, Issue 5, 2005, Pages 0764-0776

  Tanaka, Masahiro ^a   Bateman, Raynard ^a   Rauh, Daniel ^a   Vaisberg, Eugeni ^b   Ramachandani, Shyam ^b   Zhang, Chao ^a   Hansen, Kirk C ^c   Burlingame, Alma L ^c   Trautman, Jay K ^b   Shokat, Kevan M ^a   Adams, Cynthia L ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Cytokinetics Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTYL 3 (4 CHLOROPHENYL) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 AMINE; 3 (1 TERT BUTYL 4 AMINO 1H PYRAZOLO[3,4 D]PYRIMIDIN 3 YL)PHENOL; AMINE; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; CARBONYL REDUCTASE; DAUNORUBICIN; OXIDOREDUCTASE INHIBITOR; PHENOL DERIVATIVE; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE;

ARTICLE; AUTOMATION; CELL NUCLEUS; CELL STRUCTURE; CELL TYPE; CONTROLLED STUDY; GENE TARGETING; GOLGI COMPLEX; HUMAN; HUMAN CELL; MICROTUBULE; MOLECULAR DYNAMICS; PHENOTYPE; APOPTOSIS; CELL; CELL FUNCTION; CELL LINE; CHEMISTRY; COMPUTER PROGRAM; CYTOLOGY; FEMALE; IMAGE PROCESSING; METHODOLOGY; MOLECULAR GENETICS; PROTEIN CONFORMATION; TUMOR CELL LINE; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

ALCOHOL OXIDOREDUCTASES; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; CELL PHYSIOLOGY; CELLS; CELLULAR STRUCTURES; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SOFTWARE;

EID: 21744448078     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0030128     Document Type: Article

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