Diallyl trisulfide selectively causes bax- and bak-mediated apoptosis in human lung cancer cells

Environmental and Molecular Mutagenesis

Volumn 50, Issue 3, 2009, Pages 201-212

  Xiao, Dong ^a   Zeng, Yan ^a   Hahm, Eun Ryeong ^a   Kim, Young Ae ^a   Ramalingam, Suresh ^b   Singh, Shivendra V ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Bak; Bax; Diallyl trisulfide; Lung cancer

Indexed keywords

ALLYL SULFIDE; CYCLIN DEPENDENT KINASE 1; DIALLYL DISULFIDE; DIALLYL TRISULFIDE; ORGANOSULFUR DERIVATIVE; PROTEIN BAK; PROTEIN BAX; PROTEIN BID; ALLYL COMPOUND; BAK1 PROTEIN, HUMAN; BAX PROTEIN, HUMAN; BID PROTEIN, MOUSE; SULFIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG INHIBITION; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; LUNG CANCER; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; ANIMAL; BIOSYNTHESIS; BRONCHUS; CELL CYCLE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; FIBROBLAST; FLUORESCENCE MICROSCOPY; GARLIC; GENETIC TRANSFECTION; GENETICS; IMMUNOBLOTTING; ISOLATION AND PURIFICATION; LUNG TUMOR; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ALLIUM SATIVUM; ANIMALIA; PHOS;

ALLYL COMPOUNDS; ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BRONCHI; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; EPITHELIAL CELLS; FIBROBLASTS; GARLIC; HUMANS; IMMUNOBLOTTING; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; SULFIDES; TRANSFECTION;

EID: 63049105131     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20431     Document Type: Article

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