Anti-inflammatory effects of the genus Bifidobacterium on macrophages by modification of phospho-IκB and SOCS gene expression

International Journal of Experimental Pathology

Volumn 90, Issue 2, 2009, Pages 131-140

  Okada, Yoshikiyo ^a   Tsuzuki, Yoshikazu ^a   Hokari, Ryota ^a   Komoto, Shunsuke ^a   Kurihara, Chie ^a   Kawaguchi, Atsushi ^a   Nagao, Shigeaki ^a   Miura, Soichiro ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Bifidobacterium; I B ; LPS; Macrophages; Probiotics; Proinflammatory cytokines; SOCS

Indexed keywords

ATCC 15697; ATCC 15700; ATCC 15703; ATCC 19433; I KAPPA B; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROBIOTIC AGENT; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIFIDOBACTERIUM ADOLESCENTIS; BIFIDOBACTERIUM BREVE; BIFIDOBACTERIUM LONGUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENTEROCOCCUS FAECALIS; GENE EXPRESSION REGULATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; BIFIDOBACTERIUM; CELL LINE; CYTOKINES; ENTEROCOCCUS FAECALIS; GENE EXPRESSION REGULATION; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROBIOTICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 62749161435     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2008.00632.x     Document Type: Article

References (33)

1. Baetz A., Frey M., Heeg K., Dalpke A.H. (2004) Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells. J. Biol. Chem. 279, 54708 54715.
2. Balish E. Warner T. (2002) Enterococcus faecalis induces inflammatory bowel disease in interleukin-10 knockout mice. Am. J. Pathol. 160, 2253 2257.
3. Beveridge T.J. (1981) Ultrastructure, chemistry, and function of the bacterial wall. Int. Rev. Cytol. 72, 229 317.
4. Bogdan C., Vodovotz Y., Nathan C. (1991) Macrophage deactivation by interleukin 10. J. Exp. Med. 174, 1549 1555.
5. Caradonna L., Amati L., Magrone T., Pellegrino N.M., Jirillo E., Caccavo D. (2000) Enteric bacteria, lipopolysaccharides and related cytokines in inflammatory bowel disease: biological and clinical significance. J. Endotoxin Res. 6, 205 214.
6. Chinen T., Kobayashi T., Ogata H. et al. (2006) Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved. Gastroenterology 130, 373 388.
7. Chong M.M., Metcalf D., Jamieson E., Alexander W.S., Kay T.W. (2005) Suppressor of cytokine signaling-1 in T cells and macrophages is critical for preventing lethal inflammation. Blood 106, 1668 1675.
8. Crespo A., Filla M.B., Russell S.W., Murphy W.J. (2000) Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: partial role of autocrine/paracrine interferon-alpha/beta. Biochem. J. 349, 99 104.
9. Dalpke A.H., Opper S., Zimmermann S., Heeg K. (2001) Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs. J. Immunol. 166, 7082 7089.
10. Davidson N.J., Hudak S.A., Lesley R.E., Menon S., Leach M.W., Rennick D.M. (1998) IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice. J. Immunol. 161, 3143 3149.
11. Dianda L., Hanby A.M., Wright N.A., Sebesteny A., Hayday A.C., Owen M.J. (1997) T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am. J. Pathol. 150, 91 97.
12. Ding Y., Chen D., Tarcsafalvi A., Su R., Qin L., Bromberg J.S. (2003) Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses. J. Immunol. 170, 1383 1391.
13. Ewaschuk J.B. Dieleman L.A. (2006) Probiotics and prebiotics in chronic inflammatory bowel diseases. World J Gastroenterol 12, 5941 5950.
14. Ghosh S. Karin M. (2002) Missing pieces in the NF-kappaB puzzle. Cell 109 (Suppl. S81 S96.
15. He F., Morita H., Ouwehand A.C. et al. (2002) Stimulation of the secretion of pro-inflammatory cytokines by Bifidobacterium strains. Microbiol. Immunol. 46, 781 785.
16. Hoarau C., Lagaraine C., Martin L., Velge-Roussel F., Lebranchu Y. (2006) Supernatant of Bifidobacterium breve induces dendritic cell maturation, activation, and survival through a Toll-like receptor 2 pathway. J. Allergy Clin. Immunol. 117, 696 702.
17. Imaoka A., Shima T., Kato K. et al. (2008) Anti-inflammatory activity of probiotic Bifidobacterium: Enhancement of IL-10 production in peripheral blood mononuclear cells from ulcerative colitis patients and inhibition of IL-8 secretion in HT-29 cells. World J Gastroenterol 14, 2511 2516.
18. Iwabuchi N., Takahashi N., Xiao J.Z., Miyaji K., Iwatsuki K. (2007) In vitro Th1 cytokine-independent Th2 suppressive effects of bifidobacteria. Microbiol. Immunol. 51, 649 660.
19. Kato S., Hokari R., Matsuzaki K. et al. (2000) Amelioration of murine experimental colitis by inhibition of mucosal addressin cell adhesion molecule-1. J. Pharmacol. Exp. Ther. 295, 183 189.
20. Kinjyo I., Hanada T., Inagaki-Ohara K. et al. (2002) SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 17, 583 591.
21. Liew F.Y., Xu D., Brint E.K., O'Neill L.A. (2005) Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5, 446 458.
22. Mansell A., Smith R., Doyle S.L. et al. (2006) Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat. Immunol. 7, 148 155.
23. Marcinkiewicz J., Ciszek M., Bobek M. et al. (2007) Differential inflammatory mediator response in vitro from murine macrophages to lactobacilli and pathogenic intestinal bacteria. Int. J. Exp. Pathol. 88, 155 164.
24. Miura S., Tsuzuki Y., Kurose I. et al. (1996) Endotoxin stimulates lymphocyte-endothelial interactions in rat intestinal Peyer's patches and villus mucosa. Am. J. Physiol. 271, G282 G292.
25. Monteleone G., Biancone L., Marasco R. et al. (1997) Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 112, 1169 1178.
26. Murch S.H., Braegger C.P., Walker-Smith J.A., MacDonald T.T. (1993) Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease. Gut 34, 1705 1709.
27. Parronchi P., Romagnani P., Annunziato F. et al. (1997) Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am. J. Pathol. 150, 823 832.
28. Poltorak A., He X., Smirnova I. et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085 2088.
29. Sellon R.K., Tonkonogy S., Schultz M. et al. (1998) Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect. Immun. 66, 5224 5231.
30. Shibolet O. Podolsky D.K. (2007) TLRs in the Gut. IV. Negative regulation of Toll-like receptors and intestinal homeostasis: addition by subtraction. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G1469 G1473.
31. Stoiber D., Kovarik P., Cohney S., Johnston J.A., Steinlein P., Decker T. (1999) Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma. J. Immunol. 163, 2640 2647.
32. Trinchieri G. (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3, 133 146.
33. de Waal Malefyt R., Abrams J., Bennett B., Figdor C.G., de Vries J.E. (1991) Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174, 1209 1220.