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Volumn 266, Issue 3, 2009, Pages 385-389

Cytochrome P4502A6 stability in a mini organ culture model of human nasal mucosa for genotoxicology studies as detected by flow cytometry

Author keywords

Comet assay; Cytochrome P450 2A6; FACS; Genotoxicity; Human mini organ cultures

Indexed keywords

CYTOCHROME P450 2A6; XENOBIOTIC AGENT;

EID: 62549147042     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-008-0774-x     Document Type: Article
Times cited : (10)

References (40)
  • 1
    • 0023025512 scopus 로고
    • Wood-related occupations, wood dust exposure, and sinonasal cancer
    • RB Hayes M Gerin JW Raatgever A de Bruyn 1986 Wood-related occupations, wood dust exposure, and sinonasal cancer Am J Epidemiol 124 569 577
    • (1986) Am J Epidemiol , vol.124 , pp. 569-577
    • Hayes, R.B.1    Gerin, M.2    Raatgever, J.W.3    De Bruyn, A.4
  • 2
    • 8444234762 scopus 로고    scopus 로고
    • Tobacco smoking and cancer: A brief review of recent epidemiological evidence
    • Suppl 2
    • AJ Sasco MB Secretan K Straif 2004 Tobacco smoking and cancer: a brief review of recent epidemiological evidence Lung Cancer 45 Suppl 2 3 9
    • (2004) Lung Cancer , vol.45 , pp. 3-9
    • Sasco, A.J.1    Secretan, M.B.2    Straif, K.3
  • 4
    • 0142219470 scopus 로고    scopus 로고
    • Genotoxic effects of myosmine (3-(1-pyrroline-2yl)pyridine) in human lymphocytes and upper aerodigestive tract epithelial cells
    • NH Kleinsasser BC Wallner UA Harréus ER Kastenbauer W Zwickenpflug E Richter 2003 Genotoxic effects of myosmine (3-(1-pyrroline-2yl)pyridine) in human lymphocytes and upper aerodigestive tract epithelial cells Toxicology 192 171 177
    • (2003) Toxicology , vol.192 , pp. 171-177
    • Kleinsasser, N.H.1    Wallner, B.C.2    Harréus, U.A.3    Kastenbauer, E.R.4    Zwickenpflug, W.5    Richter, E.6
  • 5
    • 26444566376 scopus 로고    scopus 로고
    • The tobacco specific alcaloid nicotine demonstrates genotoxicity in human lymphocytes and lymphatic tissue
    • NH Kleinsasser A Sassen M Semmler UA Harréus AK Licht E Richter 2005 The tobacco specific alcaloid nicotine demonstrates genotoxicity in human lymphocytes and lymphatic tissue Toxicol Sci 86 309 317
    • (2005) Toxicol Sci , vol.86 , pp. 309-317
    • Kleinsasser, N.H.1    Sassen, A.2    Semmler, M.3    Harréus, U.A.4    Licht, A.K.5    Richter, E.6
  • 6
    • 0032902318 scopus 로고    scopus 로고
    • Genotoxic effect on human mucous membrane biopsies of the upper aerodigestive tract
    • U Harréus P Schmezer F Kuchenmeister H Maier 1999 Genotoxic effect on human mucous membrane biopsies of the upper aerodigestive tract Laryngorhinootologie 78 176 181
    • (1999) Laryngorhinootologie , vol.78 , pp. 176-181
    • Harréus, U.1    Schmezer, P.2    Kuchenmeister, F.3    Maier, H.4
  • 8
    • 0034643489 scopus 로고    scopus 로고
    • Comparing genotoxic sensitivities of peripheral lymphocytes and mucosa of the upper aerodigestive tract of human donors using the Comet assay
    • NH Kleinsasser BC Wallner ER Kastenbauer RK Muenzenrieder UA Harréus 2000 Comparing genotoxic sensitivities of peripheral lymphocytes and mucosa of the upper aerodigestive tract of human donors using the Comet assay Mutat Res 467 21 30
    • (2000) Mutat Res , vol.467 , pp. 21-30
    • Kleinsasser, N.H.1    Wallner, B.C.2    Kastenbauer, E.R.3    Muenzenrieder, R.K.4    Harréus, U.A.5
  • 9
    • 0030793294 scopus 로고    scopus 로고
    • Sinusoidal endothelial cells as a target for acetaminophen toxicity. Direct action versus requirement for hepatocyte activation in different mouse strains
    • LD DeLeve X Wang N Kaplowitz HM Shulman JA Bart A van der Hoek 1997 Sinusoidal endothelial cells as a target for acetaminophen toxicity. Direct action versus requirement for hepatocyte activation in different mouse strains Biochem Pharmacol 53 1339 1345
    • (1997) Biochem Pharmacol , vol.53 , pp. 1339-1345
    • Deleve, L.D.1    Wang, X.2    Kaplowitz, N.3    Shulman, H.M.4    Bart, J.A.5    Van Der Hoek, A.6
  • 10
    • 0031777993 scopus 로고    scopus 로고
    • Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: Activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P450 (c) reductase
    • E Teissier S Fennrich N Strazielle JL Daval D Ray B Schlosshauer JF Ghersi-Egea 1998 Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P450 (c) reductase Neurotoxicol 19 347 355
    • (1998) Neurotoxicol , vol.19 , pp. 347-355
    • Teissier, E.1    Fennrich, S.2    Strazielle, N.3    Daval, J.L.4    Ray, D.5    Schlosshauer, B.6    Ghersi-Egea, J.F.7
  • 11
    • 0035005696 scopus 로고    scopus 로고
    • Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelium and the Comet assay
    • NH Kleinsasser F Gamarra A Bergner BC Wallner UA Harréus J Juchhoff ER Kastenbauer RM Huber 2001 Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelium and the Comet assay ORL 63 141 147
    • (2001) ORL , vol.63 , pp. 141-147
    • Kleinsasser, N.H.1    Gamarra, F.2    Bergner, A.3    Wallner, B.C.4    Harréus, U.A.5    Juchhoff, J.6    Kastenbauer, E.R.7    Huber, R.M.8
  • 13
    • 0029906794 scopus 로고    scopus 로고
    • Effects of topical nasal steroids on human respiratory mucosa and human granulocytes in vitro
    • SK Steinsvåg R Bjerknes Ø.H Berg 1996 Effects of topical nasal steroids on human respiratory mucosa and human granulocytes in vitro Acta Otolaryngol (Stockh) 116 868 875
    • (1996) Acta Otolaryngol (Stockh) , vol.116 , pp. 868-875
    • Steinsvåg, S.K.1    Bjerknes, R.2    Berg, Ø.3
  • 15
    • 28644441289 scopus 로고    scopus 로고
    • Genotoxicity studies in mini-organ cultures of human nasal mucosa
    • BC Wallner UA Harréus F Gamarra NH Kleinsasser 2005 Genotoxicity studies in mini-organ cultures of human nasal mucosa HNO 53 1037 1046
    • (2005) HNO , vol.53 , pp. 1037-1046
    • Wallner, B.C.1    Harréus, U.A.2    Gamarra, F.3    Kleinsasser, N.H.4
  • 17
    • 0031721502 scopus 로고    scopus 로고
    • Secretory cell types and cell proliferation of human bronchial epithelial cells in an organ-culture system
    • R Bals F Gamarra A Kaps S Grundler RM Huber U Welsch 1998 Secretory cell types and cell proliferation of human bronchial epithelial cells in an organ-culture system Cell Tissue Res 293 573 577
    • (1998) Cell Tissue Res , vol.293 , pp. 573-577
    • Bals, R.1    Gamarra, F.2    Kaps, A.3    Grundler, S.4    Huber, R.M.5    Welsch, U.6
  • 18
    • 0342491759 scopus 로고    scopus 로고
    • Untersuchungen zur Genese von nasalen Karzinomen anhand von Miniorgankulturen
    • N Kleinsasser E Frei F Gamarra P Schmezer 1997 Untersuchungen zur Genese von nasalen Karzinomen anhand von Miniorgankulturen HNO 4 317
    • (1997) HNO , vol.4 , pp. 317
    • Kleinsasser, N.1    Frei, E.2    Gamarra, F.3    Schmezer, P.4
  • 20
    • 0034699514 scopus 로고    scopus 로고
    • Flow cytometric measurement of intracellular cytokines
    • P Pala T Hussell PJ Openshaw 2000 Flow cytometric measurement of intracellular cytokines J Immunol Methods 243 107 124
    • (2000) J Immunol Methods , vol.243 , pp. 107-124
    • Pala, P.1    Hussell, T.2    Openshaw, P.J.3
  • 21
    • 0025924279 scopus 로고
    • Assessment of cytokines by immunofluorescence and the paraformaldehyde-saponin procedure
    • B Sander J Andersson U Andersson 1991 Assessment of cytokines by immunofluorescence and the paraformaldehyde-saponin procedure Immunol Rev 119 65 93
    • (1991) Immunol Rev , vol.119 , pp. 65-93
    • Sander, B.1    Andersson, J.2    Andersson, U.3
  • 22
    • 0032722076 scopus 로고    scopus 로고
    • Standardisation of a procedure for quantifying surface antigens by indirect immunofluorescence
    • KB Smith SA Ellis 1999 Standardisation of a procedure for quantifying surface antigens by indirect immunofluorescence J Immunol Methods 228 29 36
    • (1999) J Immunol Methods , vol.228 , pp. 29-36
    • Smith, K.B.1    Ellis, S.A.2
  • 24
    • 0025249973 scopus 로고
    • The maintenance of cytochrome P-450 in rat hepatocyte culture: Some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system
    • AJ Paine 1990 The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system Chem Biol Interact 74 1 31
    • (1990) Chem Biol Interact , vol.74 , pp. 1-31
    • Paine, A.J.1
  • 25
    • 1642493686 scopus 로고    scopus 로고
    • Activation of signaling pathways during hepatocyte isolation: Relevance to toxicology in vitro
    • AJ Paine E Andreakos 2004 Activation of signaling pathways during hepatocyte isolation: relevance to toxicology in vitro Toxicol In Vitro 18 187 193
    • (2004) Toxicol in Vitro , vol.18 , pp. 187-193
    • Paine, A.J.1    Andreakos, E.2
  • 26
    • 0034964158 scopus 로고    scopus 로고
    • Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation
    • EL LeCluyse 2001 Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation Eur J Pharm Sci 13 343 368
    • (2001) Eur J Pharm Sci , vol.13 , pp. 343-368
    • Lecluyse, E.L.1
  • 28
    • 0043161937 scopus 로고    scopus 로고
    • Diversity of selective environmental substrates for human cytochrome P450 2A6: Alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine
    • A Le Gal Y Dreano D Lucas F Berthou 2003 Diversity of selective environmental substrates for human cytochrome P450 2A6: alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine Toxicol Lett 44 77 91
    • (2003) Toxicol Lett , vol.44 , pp. 77-91
    • Le Gal, A.1    Dreano, Y.2    Lucas, D.3    Berthou, F.4
  • 33
    • 0034770465 scopus 로고    scopus 로고
    • Human drug metabolism and the cytochromes P450: Application and relevance of in vitro models
    • K Venkatakrishnan LL Von Moltke DJ Greenblatt 2001 Human drug metabolism and the cytochromes P450: application and relevance of in vitro models J Clin Pharmacol 41 1149 1179
    • (2001) J Clin Pharmacol , vol.41 , pp. 1149-1179
    • Venkatakrishnan, K.1    Von Moltke, L.L.2    Greenblatt, D.J.3
  • 34
    • 0030679602 scopus 로고    scopus 로고
    • Metabolic capacity of nasal tissue interspecies comparisons of xenobiotic-metabolizing enzymes
    • JR Thornton-Manning AR Dahl 1997 Metabolic capacity of nasal tissue interspecies comparisons of xenobiotic-metabolizing enzymes Mutat Res 380 43 59
    • (1997) Mutat Res , vol.380 , pp. 43-59
    • Thornton-Manning, J.R.1    Dahl, A.R.2
  • 38
    • 0034665139 scopus 로고    scopus 로고
    • Human cytochrome P450 CYP2A13: Predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • T Su Z Bao QY Zhang TJ Smith JY Hong X Ding 2000 Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone Cancer Res 60 5074 5079
    • (2000) Cancer Res , vol.60 , pp. 5074-5079
    • Su, T.1    Bao, Z.2    Zhang, Q.Y.3    Smith, T.J.4    Hong, J.Y.5    Ding, X.6
  • 39
    • 13444274285 scopus 로고    scopus 로고
    • Metabolism of nicotine and cotinine by human cytochrome P450 2A13
    • Z Bao XY He X Ding S Prabhu JY Hong 2005 Metabolism of nicotine and cotinine by human cytochrome P450 2A13 Drug Metab Dispos 33 258 261
    • (2005) Drug Metab Dispos , vol.33 , pp. 258-261
    • Bao, Z.1    He, X.Y.2    Ding, X.3    Prabhu, S.4    Hong, J.Y.5


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