The tobacco alkaloid nicotine demonstrates genotoxicity in human tonsillar tissue and lymphocytes

Toxicological Sciences

Volumn 86, Issue 2, 2005, Pages 309-317

  Kleinsasser, Norbert H ^a   Sassen, Andrea W ^a   Semmler, Marzell P ^a   Harréus, Ulrich A ^b   Licht, Anna Katharina ^a   Richter, Elmar ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Comet assay; Genotoxicity; Human target cells; Nicotine

Indexed keywords

ALKALOID; DNA; NICOTINE; TOBACCO SMOKE;

ADULT; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; DATA ANALYSIS; DNA DAMAGE; DNA STRAND BREAKAGE; EXCISION REPAIR; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INCUBATION TIME; LYMPHOCYTE; LYMPHOID TISSUE; MALE; PALATINE TONSIL; PH; STATISTICAL SIGNIFICANCE; TOBACCO; TONSIL CELL;

ADULT; COMET ASSAY; DNA DAMAGE; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LYMPHOCYTES; MALE; MIDDLE AGED; NICOTINE; TOBACCO; TONSIL;

NICOTIANA TABACUM;

EID: 26444566376     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfi186     Document Type: Article

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