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Volumn 46, Issue 7, 2009, Pages 1443-1450

Elevated IL-6 expression in CD4 T cells via PKCθ and NF-κB induces Th2 cytokine production

Author keywords

Cytokines; Rodents; Signal transduction; T cells

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEAR FACTOR KAPPA B P50 SUBUNIT; PROTEIN KINASE C THETA; STAT6 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 62549111295     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.12.014     Document Type: Article
Times cited : (25)

References (30)
  • 1
    • 0036305450 scopus 로고    scopus 로고
    • T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
    • Avni O., Lee D., Macian F., Szabo S.J., Glimcher L.H., and Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat. Immunol. 3 (2002) 643-651
    • (2002) Nat. Immunol. , vol.3 , pp. 643-651
    • Avni, O.1    Lee, D.2    Macian, F.3    Szabo, S.J.4    Glimcher, L.H.5    Rao, A.6
  • 3
    • 26644473419 scopus 로고    scopus 로고
    • Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells
    • Choi E.Y., Jung K.C., Park H.J., Chung D.H., Song J.S., Yang S.D., Simpson E., and Park S.H. Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells. Immunity 23 (2005) 387-396
    • (2005) Immunity , vol.23 , pp. 387-396
    • Choi, E.Y.1    Jung, K.C.2    Park, H.J.3    Chung, D.H.4    Song, J.S.5    Yang, S.D.6    Simpson, E.7    Park, S.H.8
  • 4
    • 0030963614 scopus 로고    scopus 로고
    • Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches
    • Constant S.L., and Bottomly K. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu. Rev. Immunol. 15 (1997) 297-322
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 297-322
    • Constant, S.L.1    Bottomly, K.2
  • 5
    • 0034724201 scopus 로고    scopus 로고
    • NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta
    • Coudronniere N., Villalba M., Englund N., and Altman A. NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 3394-3399
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3394-3399
    • Coudronniere, N.1    Villalba, M.2    Englund, N.3    Altman, A.4
  • 6
    • 0035222187 scopus 로고    scopus 로고
    • A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation
    • Das J., Chen C.H., Yang L., Cohn L., Ray P., and Ray A. A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation. Nat. Immunol. 2 (2001) 45-50
    • (2001) Nat. Immunol. , vol.2 , pp. 45-50
    • Das, J.1    Chen, C.H.2    Yang, L.3    Cohn, L.4    Ray, P.5    Ray, A.6
  • 9
    • 0036889996 scopus 로고    scopus 로고
    • The two faces of IL-6 on Th1/Th2 differentiation
    • Diehl S., and Rincon M. The two faces of IL-6 on Th1/Th2 differentiation. Mol. Immunol. 39 (2002) 531-536
    • (2002) Mol. Immunol. , vol.39 , pp. 531-536
    • Diehl, S.1    Rincon, M.2
  • 11
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., and Weaver C.T. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6 (2005) 1123-1132
    • (2005) Nat. Immunol. , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 13
    • 0037371474 scopus 로고    scopus 로고
    • Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells
    • Jorritsma P.J., Brogdon J.L., and Bottomly K. Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells. J. Immunol. 170 (2003) 2427-2434
    • (2003) J. Immunol. , vol.170 , pp. 2427-2434
    • Jorritsma, P.J.1    Brogdon, J.L.2    Bottomly, K.3
  • 14
    • 0032715407 scopus 로고    scopus 로고
    • Stat6-dependent and -independent pathways for IL-4 production
    • Kaplan M.H., Wurster A.L., Smiley S.T., and Grusby M.J. Stat6-dependent and -independent pathways for IL-4 production. J. Immunol. 163 (1999) 6536-6540
    • (1999) J. Immunol. , vol.163 , pp. 6536-6540
    • Kaplan, M.H.1    Wurster, A.L.2    Smiley, S.T.3    Grusby, M.J.4
  • 15
    • 26644471257 scopus 로고    scopus 로고
    • An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population
    • Li W., Kim M.G., Gourley T.S., McCarthy B.P., Sant'Angelo D.B., and Chang C.H. An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population. Immunity 23 (2005) 375-386
    • (2005) Immunity , vol.23 , pp. 375-386
    • Li, W.1    Kim, M.G.2    Gourley, T.S.3    McCarthy, B.P.4    Sant'Angelo, D.B.5    Chang, C.H.6
  • 17
    • 0025343895 scopus 로고
    • Activation of interleukin-6 gene expression through the NF-kappa B transcription factor
    • Libermann T.A., and Baltimore D. Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Mol. Cell Biol. 10 (1990) 2327-2334
    • (1990) Mol. Cell Biol. , vol.10 , pp. 2327-2334
    • Libermann, T.A.1    Baltimore, D.2
  • 18
    • 3242790172 scopus 로고    scopus 로고
    • Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
    • Marsland B.J., Soos T.J., Spath G., Littman D.R., and Kopf M. Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J. Exp. Med. 200 (2004) 181-189
    • (2004) J. Exp. Med. , vol.200 , pp. 181-189
    • Marsland, B.J.1    Soos, T.J.2    Spath, G.3    Littman, D.R.4    Kopf, M.5
  • 19
    • 23944493698 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., and Coffman R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 175 (1986) 5-14
    • (1986) J. Immunol. , vol.175 , pp. 5-14
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 20
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy K.M., and Reiner S.L. The lineage decisions of helper T cells. Nat. Rev. Immunol. 2 (2002) 933-944
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 21
    • 0035379670 scopus 로고    scopus 로고
    • Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity
    • Nickerson K., Sisk T.J., Inohara N., Yee C.S., Kennell J., Cho M.C., Yannie II P.J., Nunez G., and Chang C.H. Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity. J. Biol. Chem. 276 (2001) 19089-19093
    • (2001) J. Biol. Chem. , vol.276 , pp. 19089-19093
    • Nickerson, K.1    Sisk, T.J.2    Inohara, N.3    Yee, C.S.4    Kennell, J.5    Cho, M.C.6    Yannie II, P.J.7    Nunez, G.8    Chang, C.H.9
  • 24
    • 0037406263 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase pathway and its role in interferon signaling
    • Platanias L.C. The p38 mitogen-activated protein kinase pathway and its role in interferon signaling. Pharmacol. Ther. 98 (2003) 129-142
    • (2003) Pharmacol. Ther. , vol.98 , pp. 129-142
    • Platanias, L.C.1
  • 25
    • 0031058726 scopus 로고    scopus 로고
    • Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells
    • Rincon M., Anguita J., Nakamura T., Fikrig E., and Flavell R.A. Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J. Exp. Med. 185 (1997) 461-469
    • (1997) J. Exp. Med. , vol.185 , pp. 461-469
    • Rincon, M.1    Anguita, J.2    Nakamura, T.3    Fikrig, E.4    Flavell, R.A.5
  • 26
    • 0034284190 scopus 로고    scopus 로고
    • MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300
    • Sisk T.J., Gourley T., Roys S., and Chang C.H. MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300. J. Immunol. 165 (2000) 2511-2517
    • (2000) J. Immunol. , vol.165 , pp. 2511-2517
    • Sisk, T.J.1    Gourley, T.2    Roys, S.3    Chang, C.H.4
  • 27
    • 0141729438 scopus 로고    scopus 로고
    • Phosphorylation of class II transactivator regulates its interaction ability and transactivation function
    • Sisk T.J., Nickerson K., Kwok R.P., and Chang C.H. Phosphorylation of class II transactivator regulates its interaction ability and transactivation function. Int. Immunol. 15 (2003) 1195-1205
    • (2003) Int. Immunol. , vol.15 , pp. 1195-1205
    • Sisk, T.J.1    Nickerson, K.2    Kwok, R.P.3    Chang, C.H.4
  • 29
    • 14044268797 scopus 로고    scopus 로고
    • IL-6 plays a unique role in initiating c-Maf expression during early stage of CD4 T cell activation
    • Yang Y., Ochando J., Yopp A., Bromberg J.S., and Ding Y. IL-6 plays a unique role in initiating c-Maf expression during early stage of CD4 T cell activation. J. Immunol. 174 (2005) 2720-2729
    • (2005) J. Immunol. , vol.174 , pp. 2720-2729
    • Yang, Y.1    Ochando, J.2    Yopp, A.3    Bromberg, J.S.4    Ding, Y.5
  • 30
    • 34247257726 scopus 로고    scopus 로고
    • Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation
    • Yu Q., Thieu V.T., and Kaplan M.H. Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation. EMBO J. 26 (2007) 2052-2060
    • (2007) EMBO J. , vol.26 , pp. 2052-2060
    • Yu, Q.1    Thieu, V.T.2    Kaplan, M.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.