Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Rα gene during Th1 differentiation

EMBO Journal

Volumn 26, Issue 8, 2007, Pages 2052-2060

  Yu, Qing ^a,b   Thieu, Vivian T ^a,b   Kaplan, Mark H ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WALTHER CANCER INSTITUTE   (United States)

Author keywords

Chromatin; Differentiation; DNA methylation; STAT proteins; T helper cell

Indexed keywords

DNA METHYLTRANSFERASE 3A; HISTONE H3; HISTONE H4; INTERLEUKIN 12; INTERLEUKIN 18 RECEPTOR ALPHA; STAT4 PROTEIN; TRICHOSTATIN A;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL TYPE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA METHYLATION; GENE EXPRESSION; GENE LOCUS; GENE REPRESSION; GENETIC ASSOCIATION; GENETIC REGULATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; STIMULATION; TH1 CELL;

ANIMALS; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; RECEPTORS, INTERLEUKIN-18; STAT4 TRANSCRIPTION FACTOR; TH1 CELLS;

EID: 34247257726     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601653     Document Type: Article

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