Novel effects of diosgenin on skin aging

Steroids

Volumn 74, Issue 6, 2009, Pages 504-511

  Tada, Yayoi ^a   Kanda, Naoko ^a   Haratake, Akinori ^a   Tobiishi, Megumi ^a   Uchiwa, Hideyo ^a   Watanabe, Shinichi ^a  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aging; cAMP; Diosgenin; Keratinocyte

Indexed keywords

ADENYLATE CYCLASE INHIBITOR; ANTISENSE OLIGODEOXYNUCLEOTIDE; BROXURIDINE; CYCLIC AMP; DIOSGENIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; CELL PROLIFERATION; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DNA SYNTHESIS; DRUG EFFICACY; DRUG SAFETY; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; NONHUMAN; OVARIECTOMY; TUMOR GROWTH;

ADENINE; ADENYLATE CYCLASE; AGED; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; CYCLIC AMP; DIOSGENIN; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; KERATINOCYTES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, HAIRLESS; MICE, NUDE; OVARIECTOMY; RECEPTORS, G-PROTEIN-COUPLED; SKIN; SKIN AGING; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN;

DIOSCOREA; DIOSCOREA VILLOSA; MUS;

EID: 62149097572     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2009.01.006     Document Type: Article

References (54)

1. McCullough J.L., and Kelly K.M. Prevention and treatment of skin aging. Ann N Y Acad Sci 1067 (2006) 323-331
2. Zava D.T., Blen M., and Duwe G. Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture. Environ Health Perspect 105 Suppl. 3 (1997) 637-645
3. Hall G., and Phillips T.J. Estrogen and skin: the effects of estrogen, menopause, and hormone replacement therapy on the skin. J Am Acad Dermatol 53 (2005) 555-568 quiz 569-72
4. Shah M.G., and Maibach H.I. Estrogen and skin. An overview. Am J Clin Dermatol 2 (2001) 143-150
5. Sator P.G., Schmidt J.B., Sator M.O., Huber J.C., and Honigsmann H. The influence of hormone replacement therapy on skin ageing: a pilot study. Maturitas 39 (2001) 43-55
6. Kanda N., and Watanabe S. 17Beta-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression. J Invest Dermatol 123 (2004) 319-328
7. Urano R., Sakabe K., Seiki K., and Ohkido M. Female sex hormone stimulates cultured human keratinocyte proliferation and its RNA- and protein-synthetic activities. J Dermatol Sci 9 (1995) 176-184
8. Hsieh C.Y., Santell R.C., Haslam S.Z., and Helferich W.G. Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo. Cancer Res 58 (1998) 3833-3838
9. Chlebowski R.T., Hendrix S.L., Langer R.D., Stefanick M.L., Gass M., Lane D., et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA 289 (2003) 3243-3253
10. Puri H.S., Jefferies T.M., and Hardman R. Diosgenin and yamogenin levels in some Indian plant samples. Planta Med 30 (1976) 118-121
11. Sharma R.D., Raghuram T.C., and Rao N.S. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 44 (1990) 301-306
12. Gupta A., Gupta R., and Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 49 (2001) 1057-1061
13. Madar Z., Abel R., Samish S., and Arad J. Glucose-lowering effect of fenugreek in non-insulin dependent diabetics. Eur J Clin Nutr 42 (1988) 51-54
14. Valette G., Sauvaire Y., Baccou J.C., and Ribes G. Hypocholesterolaemic effect of fenugreek seeds in dogs. Atherosclerosis 50 (1984) 105-111
15. Sauvaire Y., Ribes G., Baccou J.C., and Loubatieeres-Mariani M.M. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids 26 (1991) 191-197
16. Pandian R.S., Anuradha C.V., and Viswanathan P. Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats. J Ethnopharmacol 81 (2002) 393-397
17. Raju J., Patlolla J.M., Swamy M.V., and Rao C.V. Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells. Cancer Epidemiol Biomarkers Prev 13 (2004) 1392-1398
18. Scott A., Higdon K., Tucci M., Benghuzzi H., Puckett A., Tsao A., et al. The prevention of osteoporotic progression by means of steroid loaded TCPL drug delivery systems. Biomed Sci Instrum 37 (2001) 13-18
19. Komesaroff P.A., Black C.V., Cable V., and Sudhir K. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric 4 (2001) 144-150
20. Li X., Zhou L., and Gorodeski G.I. Estrogen regulates epithelial cell deformability by modulation of cortical actomyosin through phosphorylation of nonmuscle myosin heavy-chain II-B filaments. Endocrinology 147 (2006) 5236-5248
21. Haratake A., Uchida Y., Schmuth M., Tanno O., Yasuda R., Epstein J.H., et al. UVB-induced alterations in permeability barrier function: roles for epidermal hyperproliferation and thymocyte-mediated response. J Invest Dermatol 108 (1997) 769-775
22. Gottardis M.M., Jiang S.Y., Jeng M.H., and Jordan V.C. Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens. Cancer Res 49 (1989) 4090-4093
23. Ju Y.H., Allred C.D., Allred K.F., Karko K.L., Doerge D.R., and Helferich W.G. Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice. J Nutr 131 (2001) 2957-2962
24. Ponnamperuma R.M., Kirchof S.M., Trifiletti L., and De Luca L.M. Ovariectomy increases squamous metaplasia of the uterine horns and survival of SENCAR mice fed a vitamin A-deficient diet. Am J Clin Nutr 70 (1999) 502-508
25. Westhoff C., Heller D., Drosinos S., and Tancer L. Risk factors for hyperplasia-associated versus atrophy-associated endometrial carcinoma. Am J Obstet Gynecol 182 (2000) 506-508
26. Tong P.S., Mayes D.M., and Wheeler L.A. Differential effects of retinoids on DNA synthesis in calcium-regulated murine epidermal keratinocyte cultures. J Invest Dermatol 90 (1988) 861-868
27. Takahashi H., Honma M., Miyauchi Y., Nakamura S., Ishida-Yamamoto A., and Iizuka H. Cyclic AMP differentially regulates cell proliferation of normal human keratinocytes through ERK activation depending on the expression pattern of B-Raf. Arch Dermatol Res 296 (2004) 74-82
28. Fang Y., and Olah M.E. Cyclic AMP-dependent, protein kinase A-independent activation of extracellular signal-regulated kinase 1/2 following adenosine receptor stimulation in human umbilical vein endothelial cells: role of exchange protein activated by cAMP 1 (Epac1). J Pharmacol Exp Ther 322 (2007) 1189-1200
29. Kanno N., Lesage G., Phinizy J.L., Glaser S., Francis H., and Alpini G. Stimulation of α2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities. Hepatology 35 (2002) 1329-1340
30. Dumaz N., and Marais R. Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels. FEBS J 272 (2005) 3491-3504 Review
31. Tsygankova O.M., Saavedra A., Rebhun J.F., Quilliam L.A., and Meinkoth J.L. Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. Mol Cell Biol 21 (2001) 1921-1929
32. Kim S., Jee K., Kim D., Koh H., and Chung J. Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1. J Biol Chem 276 (2001) 12864-12870
33. Zivadinovic D., Gametchu B., and Watson C.S. Membrane estrogen receptor-alpha levels in MCF-7 breast cancer cells predict cAMP and proliferation responses. Breast Cancer Res 7 (2005) R101-R112
34. Razandi M., Pedram A., Merchenthaler I., Greene G.L., and Levin E.R. Plasma membrane estrogen receptors exist and functions as dimers. Mol Endocrinol 18 (2004) 2854-2865
35. Verdier-Sevrain S., Yaar M., Cantatore J., Traish A., and Gilchrest B.A. Estradiol induces proliferation of keratinocytes via a receptor mediated mechanism. FASEB J 18 (2004) 1252-1254
36. + channels of porcine isolated left anterior descending coronary artery by diosgenin. Eur J Pharmacol 502 (2004) 123-133
37. Laudenslager M.L., Wilkinson C.W., Carlisle H.J., and Hammel H.T. Energy balance in ovariectomized rats with and without estrogen replacement. Am J Physiol 238 (1980) R400-R405
38. Richard D., Rochon L., and Deshaies Y. Effects of exercise training on energy balance of ovariectomized rats. Am J Physiol 253 (1987) R740-R745
39. Wang S.L., Cai B., Cui C.B., Liu H.W., Wu C.F., and Yao X.S. Diosgenin-3-O-alpha-l-rhamnopyranosyl-(1 → 4)-beta-d-glucopyranoside obtained as a new anticancer agent from Dioscorea futschauensis induces apoptosis on human colon carcinoma HCT-15 cells via mitochondria-controlled apoptotic pathway. J Asian Nat Prod Res 6 (2004) 115-125
40. Moalic S., Liagre B., Corbiere C., Bianchi A., Dauca M., Bordji K., et al. A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. FEBS Lett 506 (2001) 225-230
41. Corbiere C., Liagre B., Bianchi A., Bordji K., Dauca M., Netter P., et al. Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells. Int J Oncol 22 (2003) 899-905
42. Hibasami H., Moteki H., Ishikawa K., Katsuzaki H., Imai K., Yoshioka K., et al. Protodioscin isolated from fenugreek (Trigonella foenumgraecum L.) induces cell death and morphological change indicative of apoptosis in leukemic cell line H-60, but not in gastric cancer cell line KATO III. Int J Mol Med 11 (2003) 23-26
43. 2+ homeostasis. Cancer Chemother Pharmacol 55 (2005) 79-90
44. Leger D.Y., Liagre B., Corbiere C., Cook-Moreau J., and Beneytout J.L. Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression. Int J Oncol 25 (2004) 555-562
45. Corbiere C., Liagre B., Terro F., and Beneytout J.L. Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells. Cell Res 14 (2004) 188-196
46. Shishodia S., and Aggarwal B.B. Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I κB kinase activation and NF-κB-regulated gene expression. Oncogene 25 (2006) 1463-1473
47. Li J., Liu X., Guo M., Liu Y., Liu S., and Yao S. Electrochemical study of breast cancer cells MCF-7 and its application in evaluating the effect of diosgenin. Anal Sci 21 (2005) 561-564
48. Yin J., Tezuka Y., Kouda K., Le Tran Q., Miyahara T., Chen Y., et al. In vivo antiosteoporotic activity of a fraction of Dioscorea spongiosa and its constituent, 22-O-methylprotodioscin. Planta Med 70 (2004) 220-226
49. McAnuff M.A., Harding W.W., Omoruyi F.O., Jacobs H., Morrison E.Y., and Asemota H.N. Hypoglycemic effects of steroidal sapogenins isolated from Jamaican bitter yam, Dioscorea polygonoides. Food Chem Toxicol 43 (2005) 1667-1672
50. Kwon C.S., Sohn H.Y., Kim S.H., Kim J.H., Son K.H., Lee J.S., et al. Anti-obesity effect of Dioscorea nipponica Makino with lipase-inhibitory activity in rodents. Biosci Biotechnol Biochem 67 (2003) 1451-1456
51. Son I.S., Kim J.H., Sohn H.Y., Son K.H., Kim J.S., and Kwon C.S. Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of Yam (Dioscorea spp.), on high-cholesterol fed rats. Biosci Biotechnol Biochem 71 (2007) 3063-3071
52. Sutherland R., Mester J., and Baulieu E.E. Tamoxifen is a potent "pure" antioestrogen in the chick oviduct. Nature 267 (1977) 434-435
53. Harper M.J., and Walpole A.L. Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes. Nature 212 (1966) 87
54. Jordan V.C., Rowsby L., Dix C.J., and Prestwich G. Dose-related effect of non-steroidal antioestrogens and non-steroidal oestrogens on the measurement of cytoplasmic oestrogen receptors in the rat and mouse uterus. J. Endocrinol 78 (1978) 71-81