Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression.

International journal of oncology

Volumn 25, Issue 3, 2004, Pages 555-562

  Leger, David Y ^a   Liagre, Bertrand ^a   Corbière, Cécile ^a   Cook Moreau, Jeanne ^a   Beneytout, Jean Louis ^a  

^a Laboratoire de Biochimie EA4021   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; CALCIUM; CYCLOOXYGENASE 2; DIOSGENIN; DNA FRAGMENT; MEMBRANE PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHOLIPASE A; PROSTAGLANDIN SYNTHASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; PTGS2 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL CYCLE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CYTOPLASM; DRUG EFFECT; ENZYMOLOGY; HUMAN; IMMUNOLOGY; METABOLISM; MITOCHONDRION; NEOPLASM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CELL CYCLE; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYTOPLASM; DIOSGENIN; DNA FRAGMENTATION; HUMANS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MITOCHONDRIA; NEOPLASMS; PHOSPHOLIPASES A; POLY(ADP-RIBOSE) POLYMERASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 8844274306     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.25.3.555     Document Type: Article

References (0)