UVB-induced alterations in permeability barrier function: Roles for epidermal hyperproliferation and thymocyte-mediated response

Journal of Investigative Dermatology

Volumn 108, Issue 5, 1997, Pages 769-775

  Haratake, Akinori ^a   Uchida, Yoshikazu ^a,b   Schmuth, Matthias ^b   Tanno, Osamu ^a   Yasuda, Rie ^a   Epstein, John H ^b   Elias, Peter M ^b   Holleran, Walter M ^b,c  

^a KANEBO LTD   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

athymic; DNA synthesis; epidermal permeability barrier; T cells

Indexed keywords

CYCLOSPORIN A; CYTARABINE; FLUOROURACIL; GLUCOCORTICOID; INDOMETACIN FARNESIL; METHOTREXATE; PRODRUG; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CONTROLLED STUDY; EPIDERMIS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN WATER LOSS; TOPICAL DRUG ADMINISTRATION; ULTRAVIOLET B RADIATION;

EID: 0030977199     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12292163     Document Type: Article

References (47)

1. Abe T, Mayuzumi J: The change and recovery of human skin barrier functions after ultraviolet light irradiation. Chem Pharm Bull(Tokyo) 27:458-462, 1979
2. Andley UP, Becker B, Hebert JS, Reddan JR, Morrison AR, Pentland AP: Enhanced prostaglandin synthesis after ultraviolet-B exposure modulates DNA synthesis of lens epithelial cells and lowers intraocular pressure in vivo. Invest Ophthalmol Visual Sci 37:142-153, 1996
3. Baker BS, Griffiths CE, Lambert S, Powles AV, Leonard JN, Valdimarsson H, Fry L: The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis. Br J Dermatol 116:503-510, 1987
4. Bissett DL, Hannon DP, Orr TV: An animal model of solar-aged skin: histological, physical, and visible changes in UV-irradiated hairless mouse skin. Photochem Photobiol 46:367-378, 1987
5. 2a and 12-HETE in human skin following ultraviolet irradiation. Br J Clin Pharmacol 10:453-457, 1980
6. 2a in human skin at 6 and 24 hours after ultraviolet B irradiation (290-320nm). Br J Clin Pharmacol 5:431-436, 1978
7. Bronaugh RL, Stewart R: Methods for in vitro percutaneous absorption studies V: permeation through damaged skin. J Pharm Sci 74:1062-1066, 1985
8. Elias PM, Menon GK: Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 24:1-26, 1991
9. Ellis CN, Gorsulowski DC, Hamilton TA, Billings JK, Brown MD, Headington JT, Cooper KD, Baadsgaard O, Duell EA, Annesley TM, Turcotte JG, Voorhees JJ: Cyclosporin improves psoriasis in double blind study. J Am Med Assoc 265:3110-3116, 1986
10. Epstein JH, Fukuyama K, Epstein WL: UVL induced stimulation of DNA synthesis in hairless mouse epidermis. J Invest Dermatol 51:445-453, 1968
11. Epstein JH, Fukuyama K, Fye K: Effects of ultraviolet radiation on the mitotic cycle and DNA, RNA and protein synthesis in mammalian epidermis in vivo. Photochem Photobiol 12:57-65, 1970
12. Fisher GJ, Duell EA, Nickoloff BJ, Annesley TM, Kowalke JK, Ellis CN, Voorhees JJ: Levels of cyclosporin in epidermis of treated psoriasis patients differentially inhibit growth of keratinocytes cultured in serum-free versus serum-containing media. J Invest Dermatol 91:142-146, 1988
13. Furue M, Gaspari AA, Katz SI: The effects of cyclosporin A on epidermal cells. II. Cyclosporin A inhibits proliferation of normal and transformed keratinocytes. J Invest Dermatol 90:796-800, 1988
14. Granelli-Piperno A: In situ hybridization for interleukin-2 and interleukin-2 receptor mRNA in T-cells activated in the presence and absence of cyclosporin A. J Exp Med 168:1649-1658, 1988
15. Gupta AK, Baadsgaard O, Ellis CN, Voorhees JJ, Cooper KD: Lymphocytes and macrophages of the epidermis and dermis in lesional psoriatic skin, but not epidermal Langerhans cells, are depleted by treatment with cyclosporin A. Arch Dermatol Res 281:219-226, 1989
16. Haratake A, Uchida Y, Mimura K, Elias PM, Holleran WM. Intrinsically aged epidermis displays diminished UVB-induced alterations in barrier function linked to decreased proliferation. J Invest Dermatol, 108:319-323, 1997
17. Ho VC, Griffiths CEM, Ellis CN, Gupta AK, McCuaig CC, Nickoloff BJ, Cooper KD, Hamilton TA, Voorhees JJ: Intralesional cyclosporin in the treatment of psoriasis. J Am Acad Dermatol 22:94-100, 1990
18. Holleran WM, Feingold KR, Man M-Q, Gao WN, Lee JM, Elias PM: Regulation of epidermal sphingolipid synthesis by permeability barrier function. J Lipid Res 32:1151-1158, 1991a
19. Holleran WM, Mao-Qiang M, Gao WN, Menon GK, Elias PM, Feingold KR: Sphingolipids are required for mammalian barrier function: inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation. J Clin Invest 88:1338-1345, 1991b
20. Holleran WM, Takagi Y, Menon GK, Legler G, Feingold KR, Elias PM: Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function. J Clin Invest 91:1656-1664, 1993
21. Kondo S, Sauder DN, Kono T, Galley KA, McKenzie RC: Differential modulation of interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) in human epidermal keratinocytes by UVB. Exp Dermatol 3:29-39, 1994
22. Kono T, Kondo S, Venner TJ, Sauder DN, McKenzie RC: Inhibition of cytokine gene expression in mouse skin by subcutaneous injection of cyclosporin. Skin Pharmacol 8:149-155, 1995
23. Kruisbeek AM, Shevach E: In vitro assays for mouse lymphocyte function. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, (eds.). Current Protocols in Immunology. Vol. 1. John Wiley & Sons, New York, 1993, p 1
24. Kupper TS, Chua AO, Flood P, McGuire J, Gubler U: Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation. J Clin Invest 80:430-436, 1987
25. LaBarca C, Paigen K: A simple, rapid and sensitive DNA assay procedure. Anal Biochem 102:344-347, 1980
26. Lamaud E, Schalla W: Influence of UV irradiation on penetration of hydrocortisone. In vivo study in hairless rat skin. Br J Dermatol 111(suppl 27):152-157, 1984
27. Lee SH, Elias PM, Proksch E, Menon GK, Mao-Qiang M, Feingold KR: Calcium and potassium are important regulators of barrier homeostasis in murine epidermis. J Clin Invest 89:530-538, 1992
28. Liou A, Elias PM, Grunfeld C, Feingold KR, Wood LC: Amphiregulin and nerve growth factor expression are regulated by barrier status in murine epidermis. J Invest Dermatol 108:73-77, 1997
29. Mao-Qiang M, Feingold KR, Jain M, Elias PM: Extracellular processing of phospholipids is required for permeability barrier homeostasis. J Lipid Res 36:1925-1935, 1995
30. McAuliffe DJ, Blank IH: Effects of UVA (320-400nm) on the barrier characteristics of the skin. J Invest Dermatol 96:758-762, 1991
31. Menon GK, Feingold KR, Elias PM: The lamellar body secretory response to barrier disruption. J Invest Dermatol 98:279-289, 1992
32. Menon GK, Feingold KR, Moser AH, Brown BE, Elias PM: De novo stereogenesis in the skin. II Regulation by cutaneous barrier requirements. J Lipids Res 26:418-427, 1985
33. Nickoloff BJ, Fisher GJ, Mitra RS, Voorhees JJ: Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes. Am J Pathol 131:12-18, 1988
34. Nickoloff BJ, Naidu Y: Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 30:535-546, 1994
35. Oxholm A, Oxholm P, Staberg B, Bendtzen K: Immunohistological detection of interleukin 1 like molecules and tumor necrosis factor in human epidermis before and after UVB irradiation in vivo. Br J Dermatol 118:369-371, 1988
36. Pentland AP, George J, Moran C, Needleman P: Cellular confluence determines injury-induced prostaglandin E2 synthesis by human keratinocyte cultures. Biochim Biophys Acta 919:71-78, 1987
37. Pentland AP, Needleman P: Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis. J Clin Invest 77:246-251, 1986
38. Powell WS: Rapid extraction of oxygenated metabolites of arachinodonic acid from biological samples using octadecylsilyl silica. Prostaglandins 20:947-957, 1980
39. Powles AV, Baker BS, McFadden J, Rutman AJ, Griffiths CEM, Fry L, Valdimarsson H: Intralesional injection of cyclosporin in psoriasis. Lancet 5:537, 1988
40. Proksch E, Elias PM, Feingold KR: Localization and regulation of epidermal HMG CoA reductase activity by barrier requirements. Biochim Biophys Acta 1083:71-79, 1991a
41. Proksch E, Feingold KR, Mao-Qiang M, Elias PM: Barrier function regulates epidermal DNA synthesis. J Clin Invest 87:1668-1673, 1991b
42. Ramirez-Bosca A, Kanitakis J, Thivolet J: Cyclosporin A exerts a cytostatic effect in vivo on human and murine epithelial cells. Cancer 66:936-940, 1990
43. Schwarz T, Luger TA: Effect of UV irradiation on epidermal cytokine production. J Photochem Photobiol B Biol 4:1-13, 1989
44. Solomon AE, Lowe NJ: Percutaneous absorption in experimental epidermal disease. Br J Dermatol 100:717-722, 1979
45. Wefers H, Melnik BC, Flür M, Bluhm C, Lehmann P, Plewig G: Influence of UV irradiation on the composition of human stratum corneum lipids. J Invest Dermatol 96:959-962, 1991
46. Won Y, Sauder DN, McKenzie RC: Cyclosporin A inhibits keratinocyte cytokine gene expression. Br J Dermatol 130:312-319, 1994
47. Wood LC, Jackson SM, Elias PM, Grunfeld C, Feingold KR: Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Invest Dermatol 90:482-487, 1992