Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4+ T lymphocytes via an interleukin-2-dependent mechanism

Cellular Immunology

Volumn 256, Issue 1-2, 2009, Pages 86-91

  Bishop, Kenneth D ^a   Harris, John E ^a   Mordes, John P ^a   Greiner, Dale L ^a   Rossini, Aldo A ^a   Czech, Michael P ^a   Phillips, Nancy E ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Anergy; PD 1; T cell; Tolerance

Indexed keywords

BETA ACTIN; CD4 ANTIGEN; CELL SURFACE RECEPTOR; DEATH RECEPTOR; INTERLEUKIN 2; PROGRAMMED DEATH 1 RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL POPULATION; CLONAL ANERGY; CONTROLLED STUDY; HORMONE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL PROLIFERATION; CLONAL ANERGY; COLUMBIDAE; CYTOCHROMES C; DNA PRIMERS; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; PHENOTYPE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION; TRANSPLANTATION TOLERANCE;

EID: 61849123188     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2009.01.008     Document Type: Article

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