B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy

Journal of Immunology

Volumn 170, Issue 7, 2003, Pages 3637-3644

  Selenko Gebauer, Nicole ^a   Majdic, Otto ^a   Szekeres, Andreas ^a   Höfler, Gerald ^b   Guthann, Elisabeth ^a   Korthäuer, Ulf ^c   Zlabinger, Gerhard ^a   Steinberger, Peter ^a   Pickl, Winfried F ^a   Stockinger, Hannes ^a   Knapp, Walter ^a   Stöckl, Johannes ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF GRAZ   (Austria)

^c Novartis Research Institute   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; COMPLEMENTARY DNA; CYTOKINE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 LIGAND; PROTEIN B7 H1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLONAL ANERGY; CYTOKINE PRODUCTION; DENDRITIC CELL; DNA LIBRARY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; MOLECULAR RECOGNITION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; SEQUENCE ANALYSIS; T LYMPHOCYTE;

EID: 0037377967     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.7.3637     Document Type: Article

References (29)

1. Steinman, R., and J. Young. 1991. Signals arising from antigen-presenting cells. Curr. Opin. Immunol. 3:361.
2. A. Lanzavecchia. 1997. Understanding the mechanisms of sustained signaling and T-cell activation. J. Exp. Med. 185:1717.
3. Steinman, R., and M. Nussenzweig. 1980. Dendritic cells: features and functions. Immunol. Rev. 53:127.
4. Banchereau, J., and R. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
5. Jonuleit, H., E. Schmitt, K. Steinbrink, and A. Enk. 2001. Dendritic cells as a tool to induce anergic and regulatory T-cells. Trends Immunol. 22:394.
6. R. Steinman. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271.
7. Thomas, R., L. Davis, and P. Lipsky. 1993. Comparative accessory cell function of human peripheral blood dendritic cells and monocytes. J. Immunol. 151:6840.
8. Geijtenbeek, T., R. Torensma, S. Van Vliet, G. Van Dujinhoven, G. Adema, Y. Van Kooyk, and C. Figdor. 2000. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 100:575.
9. Tseng, S., M. Otsuji, K. Gorski, X. Huang, J. Slansky, S. Pai, A. Shalabi, T. Shin, D. Pardoll, and H. Tsuchiya. 2001. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T-cells. J. Exp. Med. 7:839.
10. Wille, S., A. Szekeres, O. Majdic, E. Prager, G. Staffler, J. Stoeckl, D. Kunthalert, E. E. Prieschl, T. Baumruker, H. Burtscher, et al. 2001. Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells. J. Immunol. 167:5795.
11. Steinberger, P., A. Szekeres. S. Wilie, J. Stoeckl. N. Selenko, E. Prager, G. Staffler, O. Majdic, H. Stockinger, and W. Knapp. 2002. Identification of human CD93 as the phagocytic Clq receptor (ClqRp) by expression cloning. J. Leukocyte Biol. 71:133.
12. Dong, H., G. Zhu, K. Tamada, and L. Chen. 1999. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5:1365.
13. Freeman, G., A. Long, Y. Iwai, K. Bourque. T. Chernova, H. Nishimura, L. Fitz, N. Malenkovich. B. Carreno. M. Collins, et al. 2000. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192:1027.
14. Tamura, H., H. Dong, G. Zhu, G. Sica, D. Flies, K. Tamada and L. Chen. 2001. B7-H1 costimulation preferentially enhances CD28 independent T-helper cell function. Blood 97:1809.
15. Miltenyi, S., W. Muller, W. Weichel, and A. Radbruch. 1990. High gradient magnetic cell separation. Cytometry 11:1563.
16. Steinbrink, K., M. Wölfl, H. Jonuleit, J. Knop, and A. Enk. 1997. Induction of tolerance by IL-10-treated dendritic cells. J. Immunol. 159:4772.
17. Kononen, J., L. Bubendorf, A. Kallioniemi, M. Barlund, P. Schraml, S. Leighton, J. Torhorst, M. J. Mihatsch, G. Sauter, and O. P. Kallioniemi, 1998. Tissue microarrays for high-throughput molecular profiling of tumor specimens, Nat. Med. 4:844.
18. Caux, C., C. Massacrier, B. Vanbervliet, C. Barthelemy, Y. Liu, and J. Banchereau. 1994. Interleukin-10 inhibits T-cell allorecognition induced by human dendritic cells. Int. Immunol. 6:1177.
19. Cella, M., F. Sallusto, and A. Lanzavecchia. 1997. Origin, maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 9:10.
20. Mellman, I., S. Turley, and R. Steinman. 1998. Antigen processing for amateurs and professionals. Trends Cell Biol. 8:231.
21. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18:767.
22. Mellman, I., and R. Steinman. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106:255.
23. + T-cells and is overcome by IL-2. Eur. J. Immunol. 32:634.
24. Dong, H., S. E. Strome, D. R. Salomao, H. Tamura, F. Hirano, D. B. Flies, P. C. Roche, J. Lu, G. Zhu, K. Tamada. 2002. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. 8:793.
25. Sharpe, A., and G. Freeman. 2002. The B7-CD28 superfamily. Nat. Rev. Immunol. 2:116.
26. Cella, M., D. Scheidegger, K. Palmer-Lehmann, P. Lane, A. Lanzavecchia, and G. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T-cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184:747.
27. Ishida, Y., Y. Agata, K. Shibahara, and T. Honjo. 1996. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO. J. 11:3887.
28. Agata, Y., A. Kawasaki, H. Nishimura, Y. Ishida, T. Tsubata, H. Yagita, and T. Honjo. 1996. Expression of the PD-1 antigen on the surface of stimulated mouse T-and B-cells. Int. Immunol. 8:765.
29. Latchman, Y., C. Wood, T. Chernova, D. Chaudhary, M. Borde, I. Chernova, Y. Iwai, A. Long, J. Brown, R. Nunes, et al. 2001. PD-L2 is a second ligand for PD-1 and inhibits T-cell activation. Nat. Immunol. 2:261.