Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability

Food and Chemical Toxicology

Volumn 38, Issue 7, 2000, Pages 555-564

  Breinholt, V ^a   Hossaini, A ^a   Svendsen, G W ^a   Brouwer, C ^b   Nielsen, S E ^a  

^a DANISH VETERINARY AND FOOD ADMINISTRATION   (Denmark)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Absorption; Bioavailability; Estrogen receptor distribution; Flavonoids; Immature mice; In vivo estrogenicity; Isoflavonoids; Metabolism

Indexed keywords

APIGENIN; BIOCHANIN A; DAIDZEIN; DRUG METABOLITE; EQUOL; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FLAVONOID; GENISTEIN; KAEMPFEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG FECES LEVEL; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG URINE LEVEL; ESTROGEN ACTIVITY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NEWBORN; NONHUMAN; TISSUE DISTRIBUTION; UTERUS; UTERUS WEIGHT;

ANIMALS; ANIMALS, NEWBORN; APIGENIN; CELL NUCLEUS; CHROMANS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; ESTROGEN RECEPTOR ALPHA; FEMALE; FLAVONOIDS; GENISTEIN; ISOFLAVONES; KAEMPFEROLS; MICE; MICE, INBRED STRAINS; ORGAN SIZE; QUERCETIN; RECEPTORS, ESTROGEN; UTERUS;

EID: 0033867027     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(00)00046-6     Document Type: Article

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