Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function

Journal of Cell Biology

Volumn 143, Issue 4, 1998, Pages 1029-1040

  Hofmann, Christian ^a   Cheeseman, Iain M ^a   Goode, Bruce L ^a   McDonald, Kent L ^a   Barnes, Georjana ^a   Drubin, David G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anaphase; Cytoskeleton; Microtubule; Mitosis; Spindle

Indexed keywords

FUNGAL PROTEIN; PROTEIN DAM1P; PROTEIN DUO1P; UNCLASSIFIED DRUG;

ARTICLE; GENE OVEREXPRESSION; GENOTYPE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ISOLATION; SACCHAROMYCES CEREVISIAE; TEMPERATURE SENSITIVE MUTANT;

ANTIBODIES, FUNGAL; CELL CYCLE PROTEINS; CLONING, MOLECULAR; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MICROSCOPY, IMMUNOELECTRON; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MUTAGENESIS; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBCELLULAR FRACTIONS; TEMPERATURE;

SACCHAROMYCES CEREVISIAE;

EID: 0032538984     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.143.4.1029     Document Type: Article

References (39)

1. Berlin, V., C.A. Styles, and G.R. Fink. 1990. BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae. colocalizes with tubulin. J. Cell Biol. 111:2573-2586.
2. Cottingham, F.R., and M.A. Hoyt. 1997. Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J. Cell Biol. 138:1041-1053.
3. Drubin, D.G., K.G. Miller, and D. Botstein. 1988. Yeast actin-binding proteins: evidence for a role in morphogenesis. J. Cell Biol. 107:2551-2561.
4. Fields, S., and O. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature. 340:245-246.
5. Gambino, J., L.G. Bergen, and N.R. Morris. 1984. Effects of mitotic and tubulin mutations on microtubule architecture in actively growing protoplasts of Aspergillus nidulans. J. Cell Biol. 99:830-838.
6. Ghislain, M., A. Udvardy, and C. Mann. 1993. S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase. Nature. 366:358-362.
7. Goode, B.L., P.E. Denis, D. Panda, M.J. Radeke, H.P. Miller, L. Wilson, and S.C. Feinstein. 1997. Functional interactions between the proline-rich and repeat regions of Tau enhance microtubule binding and assembly. Mol. Biol. Cell. 8:353-365.
8. Hardwick, K.G. 1998. The spindle checkpoint. Trends Genet. 14:1-4.
9. Harlow, E., and D. Lane. 1988. Immunoaffinity purification. In Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 511-552.
10. Hoyt, M.A., T. Stearns, and D. Botstein. 1990. Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes. Mol. Cell. Biol. 10:223-234.
11. Hoyt, M.A., L. He, K.K. Loo, and W.S. Saunders. 1992. Two Saccharomyces cerevisiae kinesin-related gene-products required for mitotic spindle assembly. J. Cell Biol. 118:109-120.
12. Jacobs, C.W., A.E. Adams, P.J. Szaniszlo, and J.R. Pringle. 1988. Functions of microtubules in the Saccharomyces cerevisiae cell cycle. J. Cell Biol. 107:1409-1426.
13. Juang, Y.L., J. Huang, J.M. Peters, M.E. McLaughlin, C.Y. Tai, and D. Pellman. 1997. APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science. 275:1311-1314.
14. Li, R., C. Havel, J.A. Watson, and A.W. Murray. 1993. The mitotic feedback control gene MAD2 encodes the α-subunit of a prenyltransferase [published erratum appears in 371:438]. Nature. 366:82-84.
15. Machin, N.A., J.M. Lee, and G. Barnes. 1995. Microtubule stability in budding yeast: characterization and dosage suppression of a benomyl-dependent tubulin mutant. Mol. Biol. Cell. 6:1241-1259.
16. Maniatis, T., E.F. Fritsch, and J. Sambrook. 1982. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 545 pp.
17. Marschall, L.G., R.L. Jeng, J. Mulholland, and T. Stearns. 1996. Analysis of Tub4p, a yeast γ-tubulin-like protein: implications for microtubule-organizing center function. J. Cell Biol. 134:443-454.
18. Masuda, H., and W.Z. Cande. 1987. The role of tubulin polymerization during spindle elongation in vitro. Cell. 49:193-202.
19. Nicklas, R.B. 1997. How cells get the right chromosomes. Science. 275:632-637.
20. Oakley, B., and N.R. Morris. 1980. Nuclear movement is β-tubulin dependent in Aspergillus nidulans. Cell. 19:255-262.
21. Oakley, B.R. 1994. γ-Tubulin. Wiley-Liss, Inc., New York. 33-45.
22. Oakley, B.R., and J.E. Rinehart. 1985. Mitochondria and nuclei move by different mechanisms in Aspergillus nidulans. J. Cell Biol. 101:2392-2397.
23. Pasqualone, D., and T.C. Huffaker. 1994. STU1, a suppressor of a β-tubulin mutation, encodes a novel and essential component of the yeast mitotic spindle. J. Cell Biol. 127:1973-1984.
24. Pellman, D., M. Bagget, Y.H. Tu, G.R. Fink, and H. Tu. 1995. Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae [published erratum appears in 131:561]. J. Cell Biol. 130:1373-1385.
25. Pringle, J.R., A.E. Adams, D.O. Drubin, and B.K. Haarer. 1991. Immunofluorescence methods for yeast. Methods Enzymol. 194:565-602.
26. Ramer, S.W., S.J. Elledge, and R.W. Davis. 1992. Dominant genetics using a yeast genomic library under the control of a strong inducible promoter. Proc. Natl. Acad. Sci. USA. 89:11589-11593.
27. Reijo, R.A., E.M. Cooper, G.J. Beagle, and T.C. Huffaker. 1994. Systematic mutational analysis of the yeast β-tubulin gene. Mol. Biol. Cell. 5:29-43.
28. Roof, D.M., P.B. Meluh, and M.D. Rose. 1992. Kinesin-related proteins required for assembly of the mitotic spindle. J. Cell Biol. 118:95-108.
29. Rose, M.D., F. Winston, and P. Hieter. 1990. Methods in Yeast Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 198 pp.
30. Rout, M.P., and J.V. Kilmartin. 1990. Components of the yeast spindle and spindle pole body. J. Cell Biol. 111:1913-1927.
31. Rudner, A.D., and A.W. Murray. 1996. The spindle assembly checkpoint. Curr. Opin. Cell Biol. 8:773-780.
32. Saunders, W.S., and M.A. Hoyt. 1992. Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell. 70:451-458.
33. Sobel, S.G. 1997. Mini review: mitosis and the spindle pole body in Saccharomyces cerevisiae. J. Exp. Zool. 277:120-138.
34. Sobel, S.G., and M. Snyder. 1995. A highly divergent gamma-tubulin gene is essential for cell growth and proper microtubule organization in Saccharomyces cerevisiae. J. Cell Biol. 131:1775-1788.
35. Spang, A., I. Courtney, K. Grein, M. Matzner, and E. Schiebel. 1995. The Cdc31p-binding protein Kar1p is a component of the half bridge of the yeast spindle pole body. J. Cell Biol. 128:863-877.
36. Wang, P.J., and T. Huffaker. 1997. Stu2p: a microtubule-binding protein that is an essential component of the yeast spindle pole body. J. Cell Biol. 139:1271-1280.
37. Waters, J.C., and E. Salmon. 1997. Pathways of spindle assembly. Curr. Opin. Cell Biol. 9:37-43.
38. Weiss, E., and M. Winey. 1996. The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint. J. Cell Biol. 132:111-123.
39. Winey, M., L. Goetsch, P. Baum, and B. Byers. 1991. MPS1 and MPS2: novel yeast genes defining distinct steps of spindle pole body duplication. J. Cell Biol. 114:745-754.