Steroid biosynthesis inhibitors in the therapy of hypercortisolism: Theory and practice

Current Medicinal Chemistry

Volumn 15, Issue 26, 2008, Pages 2734-2747

  Igaz, P ^a   Tombol Z ^a   Szabo P M ^a   Liko I ^b   Racz K ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b GEDEON RICHTER LTD   (Hungary)

Author keywords

Adrenolytic; Cushing's syndrome; Cytochrome; Inhibition; Steroid biosynthesis; Toxicity

Indexed keywords

AMINOGLUTETHIMIDE; AMINOTRANSFERASE; CISPLATIN; DOXORUBICIN; ENZYME INHIBITOR; ETOMIDATE; ETOPOSIDE; FLUOROURACIL; HORMONE INHIBITOR; HYDROCORTISONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KETOCONAZOLE; METYRAPONE; MITOTANE; SPIRONOLACTONE; STEROID BIOSYNTHESIS INHIBITOR; STREPTOZOCIN; TRILOSTANE; UNCLASSIFIED DRUG; VINCRISTINE;

ABDOMINAL DISCOMFORT; ADRENAL CORTEX INSUFFICIENCY; ADRENALECTOMY; ALBUMINURIA; AMINOTRANSFERASE BLOOD LEVEL; ANOREXIA; ASTHENIA; ATAXIA; BLEEDING TIME; BLOOD PRESSURE; BLURRED VISION; BREATHING; CLINICAL TRIAL; CONTINUOUS INFUSION; CUSHING SYNDROME; DEPRESSION; DIARRHEA; DISORDERS OF STEROID METABOLISM; DIZZINESS; DROWSINESS; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG CHOICE; DRUG CONTRAINDICATION; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG ELIMINATION; DRUG ERUPTION; DRUG FATALITY; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG MECHANISM; DRUG MEGADOSE; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; DRUG WITHDRAWAL; EDEMA; ENDOCRINE DISEASE; ENZYME INHIBITION; ESCAPE BEHAVIOR; GAIT DISORDER; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GASTRITIS; GASTROINTESTINAL SYMPTOM; GYNECOMASTIA; HEART RATE; HEMATURIA; HEMORRHAGIC CYSTITIS; HIRSUTISM; HUMAN; HYPERCHOLESTEROLEMIA; HYPERCORTISOLISM; HYPERSALIVATION; HYPERTENSION; HYPOKALEMIA; HYPOTHYROIDISM; IMPOTENCE; IRRITABILITY; LANGUAGE DISABILITY; LETHARGY; LIVER TOXICITY; LOW DRUG DOSE; MENTAL DEFICIENCY; MINERALOCORTICOID EXCESS SYNDROME; MYOCLONUS; NAUSEA; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; OPTIC NERVE DISEASE; PARESTHESIA; PRURITUS; REVIEW; SEDATION; SIDE EFFECT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SKIN TOXICITY; SODIUM RETENTION; SOLID TUMOR; SOMNOLENCE; STEROIDOGENESIS; STRUCTURE ACTIVITY RELATION; TERATOGENICITY; TREATMENT FAILURE; UROGENITAL TRACT DISEASE; VERTIGO; VOMITING; WEAKNESS;

ANIMALS; CUSHING SYNDROME; ENZYME INHIBITORS; HUMANS; STEROIDS;

EID: 61649105562     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708786242921     Document Type: Review

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