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Volumn 22, Issue 15, 2002, Pages 6766-6772

Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter

Author keywords

Antidepressant; Chronoamperometry; Downregulation; MRNA; Serotonin transporter; Sertraline

Indexed keywords

ANTIDEPRESSANT AGENT; SEROTONIN; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

EID: 0036703989     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-15-06766.2002     Document Type: Article
Times cited : (162)

References (42)
  • 2
    • 0034667557 scopus 로고    scopus 로고
    • Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A
    • Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD (2000) Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A. J Neurosci 20:7571-7578.
    • (2000) J Neurosci , vol.20 , pp. 7571-7578
    • Bauman, A.L.1    Apparsundaram, S.2    Ramamoorthy, S.3    Wadzinski, B.E.4    Vaughan, R.A.5    Blakely, R.D.6
  • 3
    • 0027421854 scopus 로고
    • Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei
    • Bel N, Artigas F (1993) Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei. Synapse 15:243-245.
    • (1993) Synapse , vol.15 , pp. 243-245
    • Bel, N.1    Artigas, F.2
  • 4
  • 5
    • 0028018846 scopus 로고
    • Modulation of 5-HT release in the guineapig brain following long-term administration of antidepressant drugs
    • Blier P, Bouchard C (1994) Modulation of 5-HT release in the guineapig brain following long-term administration of antidepressant drugs. Br J Pharmacol 113:485-495.
    • (1994) Br J Pharmacol , vol.113 , pp. 485-495
    • Blier, P.1    Bouchard, C.2
  • 6
    • 0032125492 scopus 로고    scopus 로고
    • Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: An investigation of extrasynaptic transmission
    • Bunin MA, Wightman RM (1998) Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: An investigation of extrasynaptic transmission. J Neurosci 18:4854-4860.
    • (1998) J Neurosci , vol.18 , pp. 4854-4860
    • Bunin, M.A.1    Wightman, R.M.2
  • 7
    • 0031940196 scopus 로고    scopus 로고
    • Release and uptake rates of hydroxytryptamine in the dorsal raphe and substantia nigra reticulata of the rat brain
    • Bunin MA, Prioleau C, Mailman RB, Wightman RM (1998) Release and uptake rates of hydroxytryptamine in the dorsal raphe and substantia nigra reticulata of the rat brain. J Neurochem 70:1077-1087.
    • (1998) J Neurochem , vol.70 , pp. 1077-1087
    • Bunin, M.A.1    Prioleau, C.2    Mailman, R.B.3    Wightman, R.M.4
  • 8
    • 0027361772 scopus 로고
    • Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: Role of metabolism and effects of locally applied uptake inhibitors
    • Cass WA, Zahniser NR, Flach KA, Gerhardt GA (1993) Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: Role of metabolism and effects of locally applied uptake inhibitors. J Neurochem 61:2269-2278.
    • (1993) J Neurochem , vol.61 , pp. 2269-2278
    • Cass, W.A.1    Zahniser, N.R.2    Flach, K.A.3    Gerhardt, G.A.4
  • 10
    • 0032424241 scopus 로고    scopus 로고
    • In vivo chronoamperometric measures of extracellular serotonin clearance in rat dorsal hippocampus: Contribution of serotonin and norepinephrine transporters
    • Daws LC, Toney GM, Gerhardt GA, Frazer A (1998) In vivo chronoamperometric measures of extracellular serotonin clearance in rat dorsal hippocampus: Contribution of serotonin and norepinephrine transporters. J Pharmacol Exp Ther 286:967-976.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 967-976
    • Daws, L.C.1    Toney, G.M.2    Gerhardt, G.A.3    Frazer, A.4
  • 11
    • 0033792180 scopus 로고    scopus 로고
    • 5-HT(1B) receptor-mediated regulation of serotonin clearance in rat hippocampus in vivo
    • Daws LC, Gould GG, Teicher SD, Gerhardt GA, Frazer A (2000) 5-HT(1B) receptor-mediated regulation of serotonin clearance in rat hippocampus in vivo. J Neurochem 75:2113-2122.
    • (2000) J Neurochem , vol.75 , pp. 2113-2122
    • Daws, L.C.1    Gould, G.G.2    Teicher, S.D.3    Gerhardt, G.A.4    Frazer, A.5
  • 12
    • 0033032825 scopus 로고    scopus 로고
    • Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: Implications for the role of serotonin in the mechanism of antidepressant action
    • Delgado PL, Miller HL, Salomon RM, Licinio J, Krystal JH, Moreno FA, Heninger GR, Charney DS (1999) Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: Implications for the role of serotonin in the mechanism of antidepressant action. Biol Psychiatry 46:212-220.
    • (1999) Biol Psychiatry , vol.46 , pp. 212-220
    • Delgado, P.L.1    Miller, H.L.2    Salomon, R.M.3    Licinio, J.4    Krystal, J.H.5    Moreno, F.A.6    Heninger, G.R.7    Charney, D.S.8
  • 13
    • 0030612234 scopus 로고    scopus 로고
    • Distribution of alpha1A adrenergic receptor mRNA in the rat brain visualized by in situ hybridization
    • Domyancic AV, Morilak DA (1997) Distribution of alpha1A adrenergic receptor mRNA in the rat brain visualized by in situ hybridization. J Comp Neurol 386:358-378.
    • (1997) J Comp Neurol , vol.386 , pp. 358-378
    • Domyancic, A.V.1    Morilak, D.A.2
  • 15
    • 0033232499 scopus 로고    scopus 로고
    • Neural plasticity to stress and antidepressant treatment
    • Duman RS, Malberg J, Thome J (1999) Neural plasticity to stress and antidepressant treatment. Biol Psychiatry 46:1181-1191.
    • (1999) Biol Psychiatry , vol.46 , pp. 1181-1191
    • Duman, R.S.1    Malberg, J.2    Thome, J.3
  • 16
    • 0028786861 scopus 로고
    • Alteration of serotonin release in the guinea pig orbito-frontal cortex by selective serotonin reuptake inhibitors. Relevance to treatment of obsessive-compulsive disorder
    • El Mansari M, Bouchard C, Blier P (1995) Alteration of serotonin release in the guinea pig orbito-frontal cortex by selective serotonin reuptake inhibitors. Relevance to treatment of obsessive-compulsive disorder. Neuropsychopharmacology 13:117-127.
    • (1995) Neuropsychopharmacology , vol.13 , pp. 117-127
    • El Mansari, M.1    Bouchard, C.2    Blier, P.3
  • 18
    • 0023627477 scopus 로고
    • Characterization of the techniques of pressure-ejection and microiontophoresis using in vivo electrochemistry
    • Gerhardt GA, Palmer MR (1987) Characterization of the techniques of pressure-ejection and microiontophoresis using in vivo electrochemistry. J Neurosci Methods 22:147-159.
    • (1987) J Neurosci Methods , vol.22 , pp. 147-159
    • Gerhardt, G.A.1    Palmer, M.R.2
  • 19
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B, Jaber M, Jones SR, Wightman RM, Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 20
    • 0020431887 scopus 로고
    • Kinetics of citalopram in test animals; drug exposure in safety studies
    • Fredricson Overo K (1982) Kinetics of citalopram in test animals; drug exposure in safety studies. Prog Neuropsychopharmacol Biol Psychiatry 6:297-309.
    • (1982) Prog Neuropsychopharmacol Biol Psychiatry , vol.6 , pp. 297-309
    • Fredricson Overo, K.1
  • 21
    • 0035205403 scopus 로고    scopus 로고
    • Desensitization of 5-HT(1A) autoreceptors by a low chronic fluoxetine dose effect of the concurrent administration of WAY-100635
    • Hervás I, Vilaro MT, Romero L, Scorza MC, Mengod G, Artigas F (2001) Desensitization of 5-HT(1A) autoreceptors by a low chronic fluoxetine dose effect of the concurrent administration of WAY-100635. Neuropsychopharmacology 24:11-20.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 11-20
    • Hervás, I.1    Vilaro, M.T.2    Romero, L.3    Scorza, M.C.4    Mengod, G.5    Artigas, F.6
  • 22
    • 0344110152 scopus 로고    scopus 로고
    • Pharmacokinetics of selective serotonin reuptake inhibitors
    • Hiemke C, Hartter S (2000) Pharmacokinetics of selective serotonin reuptake inhibitors. Pharmacol Ther 85:11-28.
    • (2000) Pharmacol Ther , vol.85 , pp. 11-28
    • Hiemke, C.1    Hartter, S.2
  • 23
    • 0028018469 scopus 로고
    • Chronic treatment with citalopram facilitates the effect of a challenge dose on cortical serotonin output: Role of presynaptic 5-HT1A receptors
    • Invernizzi R, Bramante M, Samanin R (1994) Chronic treatment with citalopram facilitates the effect of a challenge dose on cortical serotonin output: Role of presynaptic 5-HT1A receptors. Eur J Pharmacol 260:243-246.
    • (1994) Eur J Pharmacol , vol.260 , pp. 243-246
    • Invernizzi, R.1    Bramante, M.2    Samanin, R.3
  • 24
    • 0030438778 scopus 로고    scopus 로고
    • Onset of antidepressant activity: Reexamining the structure of depression and multiple actions of drugs
    • Katz MM, Koslow SH, Frazer A (1996/1997) Onset of antidepressant activity: Reexamining the structure of depression and multiple actions of drugs. Depress Anxiety 4:257-267.
    • (1996) Depress Anxiety , vol.4 , pp. 257-267
    • Katz, M.M.1    Koslow, S.H.2    Frazer, A.3
  • 25
    • 0023891690 scopus 로고
    • Quantitative autoradiography of serotonin uptake sites in rat brain using [3H]cyanoimipramine
    • Kovachich GB, Aronson CE, Brunswick DJ, Frazer A (1988) Quantitative autoradiography of serotonin uptake sites in rat brain using [3H]cyanoimipramine. Brain Res 454:78-88.
    • (1988) Brain Res , vol.454 , pp. 78-88
    • Kovachich, G.B.1    Aronson, C.E.2    Brunswick, D.J.3    Frazer, A.4
  • 26
    • 0029064827 scopus 로고
    • Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-hydroxytryptamine measured in vivo
    • Kreiss DS, Lucki I (1995) Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-hydroxytryptamine measured in vivo. J Pharmacol Exp Ther 274:866-876.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 866-876
    • Kreiss, D.S.1    Lucki, I.2
  • 27
    • 0021591318 scopus 로고
    • Distribution of citalopram in the blood serum and in the central nervous system of rats after single and multiple dosage
    • Melzacka M, Rurak A, Adamus A, Daniel W (1984) Distribution of citalopram in the blood serum and in the central nervous system of rats after single and multiple dosage. Pol J Pharmacol Pharm 36:675-682.
    • (1984) Pol J Pharmacol Pharm , vol.36 , pp. 675-682
    • Melzacka, M.1    Rurak, A.2    Adamus, A.3    Daniel, W.4
  • 28
    • 0030993317 scopus 로고    scopus 로고
    • The serotonergic and noradrenergic systems of the hippocampus: Their interactions and the effects of antidepressant treatments
    • Mongeau R, Blier P, de Montigny C (1997) The serotonergic and noradrenergic systems of the hippocampus: Their interactions and the effects of antidepressant treatments. Brain Res Brain Res Rev 23:145-195.
    • (1997) Brain Res Brain Res Rev , vol.23 , pp. 145-195
    • Mongeau, R.1    Blier, P.2    De Montigny, C.3
  • 29
    • 0028900441 scopus 로고
    • Interaction between diffusion and Michaelis-Menten uptake of dopamine following iontophoresis in striatum
    • Nicholson C (1995) Interaction between diffusion and Michaelis-Menten uptake of dopamine following iontophoresis in striatum. Biophys J 68:1699-1715.
    • (1995) Biophys J , vol.68 , pp. 1699-1715
    • Nicholson, C.1
  • 30
    • 0019731754 scopus 로고
    • Ions diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum
    • Nicholson C, Phillips JM (1981) Ions diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum. J Physiol (Lond) 321:225-257.
    • (1981) J Physiol (Lond) , vol.321 , pp. 225-257
    • Nicholson, C.1    Phillips, J.M.2
  • 31
    • 0031727557 scopus 로고    scopus 로고
    • The serotonin transporter and depression
    • Owens MJ, Nemeroff CB (1998) The serotonin transporter and depression. Depress Anxiety 8:5-12.
    • (1998) Depress Anxiety , vol.8 , pp. 5-12
    • Owens, M.J.1    Nemeroff, C.B.2
  • 33
    • 0345540627 scopus 로고    scopus 로고
    • Autoregulation of serotonin neurons: Role in antidepressant drug action
    • Piñeyro G, Blier P (1999) Autoregulation of serotonin neurons: Role in antidepressant drug action. Pharmacol Rev 51:533-591.
    • (1999) Pharmacol Rev , vol.51 , pp. 533-591
    • Piñeyro, G.1    Blier, P.2
  • 34
    • 0028220927 scopus 로고
    • Desensitization of the neuronal 5-HT carrier following its long-term blockade
    • Piñeyro G, Blier P, Dennis T, de Montigny C (1994) Desensitization of the neuronal 5-HT carrier following its long-term blockade. J Neurosci 14:3036-3047.
    • (1994) J Neurosci , vol.14 , pp. 3036-3047
    • Piñeyro, G.1    Blier, P.2    Dennis, T.3    De Montigny, C.4
  • 35
    • 0033957413 scopus 로고    scopus 로고
    • Second messenger-regulated protein kinases in the brain: Their functional role and the action of antidepressant drugs
    • Popoli M, Brunello N, Perez J, Racagni G (2000) Second messenger-regulated protein kinases in the brain: Their functional role and the action of antidepressant drugs. J Neurochem 74:21-33.
    • (2000) J Neurochem , vol.74 , pp. 21-33
    • Popoli, M.1    Brunello, N.2    Perez, J.3    Racagni, G.4
  • 37
    • 0033618638 scopus 로고    scopus 로고
    • Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants
    • Ramamoorthy S, Blakely RD (1999) Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants. Science 285:763-766.
    • (1999) Science , vol.285 , pp. 763-766
    • Ramamoorthy, S.1    Blakely, R.D.2
  • 38
    • 0028214689 scopus 로고
    • Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine
    • Rutter JJ, Gundlah C, Auerbach SB (1994) Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine. Neurosci Lett 171:183-186.
    • (1994) Neurosci Lett , vol.171 , pp. 183-186
    • Rutter, J.J.1    Gundlah, C.2    Auerbach, S.B.3
  • 39
    • 0029795359 scopus 로고    scopus 로고
    • Chronic desipramine and fluoxetine differentially affect extracellular dopamine in the rat prefrontal cortex
    • Tanda G, Frau R, Di Chiara G (1996) Chronic desipramine and fluoxetine differentially affect extracellular dopamine in the rat prefrontal cortex. Psychopharmacology (Berl) 127:83-87.
    • (1996) Psychopharmacology (Berl) , vol.127 , pp. 83-87
    • Tanda, G.1    Frau, R.2    Di Chiara, G.3
  • 40
    • 0020361582 scopus 로고
    • Analysis of nonlinear diffusion problem with Michaelis-Menten kinetics by an integral equation method
    • Tosaka N, Miyake S (1982) Analysis of nonlinear diffusion problem with Michaelis-Menten kinetics by an integral equation method. Bull Math Biol 44:841-849.
    • (1982) Bull Math Biol , vol.44 , pp. 841-849
    • Tosaka, N.1    Miyake, S.2
  • 41
    • 0033546936 scopus 로고    scopus 로고
    • Serotonin transporter production and degradation rates: Studies with RTI-76
    • Vicentic A, Battaglia G, Carroll FI, Kuhar MJ (1999) Serotonin transporter production and degradation rates: Studies with RTI-76. Brain Res 841:1-10.
    • (1999) Brain Res , vol.841 , pp. 1-10
    • Vicentic, A.1    Battaglia, G.2    Carroll, F.I.3    Kuhar, M.J.4
  • 42
    • 0025241289 scopus 로고
    • Control of dopamine extracellular concentration in rat striatum by impulse flow and uptake
    • Wightman RM, Zimmerman JB (1990) Control of dopamine extracellular concentration in rat striatum by impulse flow and uptake. Brain Res Rev 15:135-144.
    • (1990) Brain Res Rev , vol.15 , pp. 135-144
    • Wightman, R.M.1    Zimmerman, J.B.2


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