Mechanisms for picrotoxin block of α2 homomeric glycine receptors

Journal of Biological Chemistry

Volumn 281, Issue 7, 2006, Pages 3841-3855

  Wang, Dian Shi ^a,d   Mangin, Jean Marie ^b   Moonen, Gustave ^a   Rigo, Jean Michel ^b,c   Legendre, Pascal ^a  

^a CNRS   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c HASSELT UNIVERSITY   (Belgium)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; MOLECULAR STRUCTURE; TOXIC MATERIALS;

AMINOBUTYRIC ACID; HOMOMERIC GLYCINE;

AMINO ACIDS;

GLYCINE; GLYCINE RECEPTOR; PICROTOXIN; GLRA2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; ELECTRIC POTENTIAL; KINETICS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN CONFORMATION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; CHO CELL; DOSE RESPONSE; DRUG ANTAGONISM; HAMSTER; PROBABILITY;

CRICETULUS GRISEUS;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCINE; KINETICS; MARKOV CHAINS; MODELS, BIOLOGICAL; PICROTOXIN; RECEPTORS, GLYCINE;

EID: 33645212296     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511022200     Document Type: Article

References (41)

1. Legendre, P. (2001) Cell. Mol. Life Sci. 58, 760-793
2. Grudzinska, J., Schemm, R., Haeger, S., Nicke, A., Schmalzing, G., Betz, H., and Laube, B. (2005) Neuron 45, 727-739
3. Pribilla, I., Takagi, T., Langosch, D., Bormann, J., and Betz, H. (1992) EMBO J. 11, 4305-4311
4. Lynch, J. W. (2004) Physiol. Rev. 84, 1051-1095
5. Ffrench-Constant, R. H., Rocheleau, T. A., Steichen, J. C., and Chalmers, A. E. (1993) Nature 363, 449-451
6. Gurley, D., Amin, J., Ross, P. C., Weiss, D. S., and White, G. (1995) Receptors Channels 3, 13-20
7. Xu, M., Covey, D. F., and Akabas, M. H. (1995) Biophys. J. 69, 1858-1867
8. Zhang, D., Pan, Z. H., Zhang, X., Brideau, A. D., and Lipton, S. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11756-11760
9. Etter, A., Cully, D. F., Liu, K. K., Reiss, B., Vassilatis, D. K., Schaeffer, J. M., and Arena, J. P. (1999) J. Neurochem. 72, 318-326
10. Buhr, A., Wagner, C., Fuchs, K., Sieghart, W., and Sigel, E. (2001) J. Biol. Chem. 276, 7775-7781
11. Shan, Q., Haddrill, J. L., and Lynch, J. W. (2001) J. Neurochem. 76, 1109-1120
12. Dibas, M. I., Gonzales, E. B., Das, P., Bell-Horner, C. L., and Dillon, G. H. (2002) J. Biol. Chem. 277, 9112-9117
13. Das, P., and Dillon, G. H. (2005) J. Pharmacol. Exp. Ther. 314, 320-328
14. Hawthorne, R., and Lynch, J. W. (2005) J. Biol. Chem. 280, 35836-35843
15. Inoue, M., and Akaike, N. (1988) Neurosci. Res. 5, 380-394
16. Newland, C. F., and Cull-Candy, S. G. (1992) J. Physiol. 447, 191-213
17. Qian, H., Pan, Y., Zhu, Y., and Khalili, P. (2005) Mol. Pharmacol. 67, 470-479
18. Lynch, J. W., Rajendra, S., Barry, P. H., and Schofield, P. R. (1995) J. Biol. Chem. 270, 13799-13806
19. Legendre, P. (1997) J. Neurophysiol. 77, 2400-2415
20. Yoon, K. W., Wotring, V. E., and Fuse, T. (1998) Neuroscience 87, 807-815
21. Kuhse, J., Kuryatov, A., Maulet, Y., Malosio, M. L., Schmieden, V., and Betz, H. (1991) FEBS Lett. 283, 73-77
22. Triller, A., Seitanidou, T., Franksson, O., and Korn, H. (1990) New Biol. 2, 637-641
23. Mangin, J. M., Baloul, M., Prado De Carvalho, L., Rogister, B., Rigo, J. M., and Legendre, P. (2003) J. Physiol. 553, 369-386
24. Flint, A. C., Liu, X., and Kriegstein, A. R. (1998) Neuron 20, 43-53
25. Mangin, J. M., Nguyen, L., Gougnard, C., Hans, G., Rogister, B., Belachew, S., Moonen, G., Legendre, P., and Rigo, J. M. (2005) Mol. Pharmacol. 67, 1783-1796
26. Hamill, O. P., Marty, A., Neher, E., Sakmann, B., and Sigworth, F. J. (1981) Pflugers Arch. 391, 85-100
27. Franke, C., Hatt, H., and Dudel, J. (1987) Neurosci. Lett. 77, 199-204
28. Legendre, P. (1998) J. Neurosci. 18, 2856-2870
29. Clements, J. D., and Westbrook, G. L. (1991) Neuron 7, 605-613
30. Aldrich, R. W., Corey, D. P., and Stevens, C. F. (1983) Nature 306, 436-441
31. Sigworth, F. J., and Sine, S. M. (1987) Biophys. J. 52, 1047-1054
32. Maconochie, D. J., and Steinbach, J. H. (1995) J. Gen. Physiol. 106, 113-147
33. Legendre, P., Ali, D. W., and Drapeau, P. (2000) J. Neurosci. 20, 140-148
34. Colquhoun, D., and Hawkes, A. G. (1995) in Single-channel Recording (Sakmann, B., and Neher, E., eds) 2nd Ed., pp. 397-479, Plenum Press, New York
35. Adelsberger, H., Brunswieck, S., and Dudel, J. (1998) Eur. J. Neurosci. 10, 179-187
36. Burzomato, V., Beato, M., Groot-Kormelink, P. J., Colquhoun, D., and Sivilotti, L. G. (2004) J. Neurosci. 24, 10924-10940
37. Gentet, L. J., and Clements, J. D. (2002) J. Physiol. 544, 97-106
38. Zhorov, B. S., and Bregestovski, P. D. (2000) Biophys. J. 78, 1786-1803
39. Harvey, R. J., Schmieden, V., Von Holst, A., Laube, B., Rohrer, H., and Betz, H. (2000) Eur. J. Neurosci. 12, 994-1001
40. Rundstrom, N., Schmieden, V., Betz, H., Bormann, J., and Langosch, D. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8950-8954
41. Colquhoun, D., and Sivilotti, L. G. (2004) Trends Neurosci. 27, 337-344