Synthesis and in vitro antitumor activity of new quinoxaline derivatives

European Journal of Medicinal Chemistry

Volumn 44, Issue 4, 2009, Pages 1579-1591

  Corona, Paola ^a   Carta, Antonio ^a   Loriga, Mario ^a   Vitale, Gabriella ^a   Paglietti, Giuseppe ^a  

^a UNIVERSITY OF SASSARI   (Italy)

Author keywords

5,7 Diamino 3 phenyl 2 benzylamino, 2 phenoxy and 2 phenylthio substituted quinoxalines; Antitumor activity

Indexed keywords

5,7 DIAMINO 3 PHENYL 2 [(3,4 DICHLORO BENZYL)AMINO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4 DICHLORO)PHENOXY]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4 DICHLORO)PHENYLTHIO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4 DIMETHOXY BENZYL)AMINO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4 DIMETHOXY)PHENOXY]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4 DIMETHOXY)PHENYLTHIO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4,5 TRIMETHOXY BENZYL)AMINO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,4,5 TRIMETHOXY)PHENOXY]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,5 DIMETHOXY BENZYL)AMINO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(3,5 DIMETHOXY)PHENOXY]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(4 FLUORO BENZYL)AMINO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(4 FLUORO)PHENOXY]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(4 FLUORO)PHENYLTHIO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(4 METHOXY BENZYL)AMINO]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(4 METHOXY)PHENOXY]QUINOXALINE; 5,7 DIAMINO 3 PHENYL 2 [(4 METHOXY)PHENYLTHIO]QUINOXALINE; ANTINEOPLASTIC AGENT; N [4 (5,7 DIAMINO 3 PHENYLQUINOXALIN 2 YLOXY)BENZOYL]GLUTAMIC ACID DIETHYL ESTER; N [4 [(5,7 DIAMINO 3 PHENYLQUINOXALIN 2 YLAMINO)METHYL]BENZOYL]GLUTAMIC ACID DIETHYL ESTER; N [4(5,7 DIAMINO 3 PHENYLQUINOXALIN 2 YLTHIO) BENZOYL]GLUTAMIC ACID DIETHYL ESTER; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN MCF 7; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; KIDNEY CANCER; LEUKEMIA; LUNG NON SMALL CELL CANCER; MELANOMA; OVARY CANCER; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; HUMANS; QUINOXALINES;

EID: 61349113364     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.07.025     Document Type: Article

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